Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse
Schmitt-John T, Drepper C, Mussmann A, Hahn P, Kuhlmann M, Thiel C, Hafner M, Lengeling A, Heimann P, Jones JM, Meisler MH, et al. (2005)
Nature Genetics 37(11): 1213-1215.
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Autor*in
Schmitt-John, T;
Drepper, C;
Mussmann, A;
Hahn, P;
Kuhlmann, M;
Thiel, C;
Hafner, M;
Lengeling, A;
Heimann, PeterUniBi;
Jones, JM;
Meisler, MH;
Jockusch, HaraldUniBi
Einrichtung
Abstract / Bemerkung
Vacuolar-vesicular protein sorting (Vps) factors are involved in vesicular trafficking in eukaryotic cells. We identified the missense mutation L967Q in Vps54 in the wobbler mouse, an animal model of amyotrophic lateral sclerosis, and also characterized a lethal allele, Vps54(beta-geo). Motoneuron survival and spermiogenesis are severely compromised in the wobbler mouse, indicating that Vps54 has an essential role in these processes.
Erscheinungsjahr
2005
Zeitschriftentitel
Nature Genetics
Band
37
Ausgabe
11
Seite(n)
1213-1215
ISSN
1061-4036
Page URI
https://pub.uni-bielefeld.de/record/1601626
Zitieren
Schmitt-John T, Drepper C, Mussmann A, et al. Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse. Nature Genetics. 2005;37(11):1213-1215.
Schmitt-John, T., Drepper, C., Mussmann, A., Hahn, P., Kuhlmann, M., Thiel, C., Hafner, M., et al. (2005). Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse. Nature Genetics, 37(11), 1213-1215. https://doi.org/10.1038/ng1661
Schmitt-John, T, Drepper, C, Mussmann, A, Hahn, P, Kuhlmann, M, Thiel, C, Hafner, M, et al. 2005. “Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse”. Nature Genetics 37 (11): 1213-1215.
Schmitt-John, T., Drepper, C., Mussmann, A., Hahn, P., Kuhlmann, M., Thiel, C., Hafner, M., Lengeling, A., Heimann, P., Jones, J. M., et al. (2005). Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse. Nature Genetics 37, 1213-1215.
Schmitt-John, T., et al., 2005. Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse. Nature Genetics, 37(11), p 1213-1215.
T. Schmitt-John, et al., “Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse”, Nature Genetics, vol. 37, 2005, pp. 1213-1215.
Schmitt-John, T., Drepper, C., Mussmann, A., Hahn, P., Kuhlmann, M., Thiel, C., Hafner, M., Lengeling, A., Heimann, P., Jones, J.M., Meisler, M.H., Jockusch, H.: Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse. Nature Genetics. 37, 1213-1215 (2005).
Schmitt-John, T, Drepper, C, Mussmann, A, Hahn, P, Kuhlmann, M, Thiel, C, Hafner, M, Lengeling, A, Heimann, Peter, Jones, JM, Meisler, MH, and Jockusch, Harald. “Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse”. Nature Genetics 37.11 (2005): 1213-1215.
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Vacuolar protein sorting-associated protein 54 (UNIPROT: Q5SRW8)
Organism: Mus musculus
Download in FASTA format
Organism: Mus musculus
Download in FASTA format
Vacuolar protein sorting-associated protein 54 (UNIPROT: Q5SPW0)
Organism: Mus musculus
Download in FASTA format
Organism: Mus musculus
Download in FASTA format
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An early onset progressive motor neuron disorder in Scyl1-deficient mice is associated with mislocalization of TDP-43.
Pelletier S, Gingras S, Howell S, Vogel P, Ihle JN., J Neurosci 32(47), 2012
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Pelletier S, Gingras S, Howell S, Vogel P, Ihle JN., J Neurosci 32(47), 2012
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Molecular identification of t(w5): Vps52 promotes pluripotential cell differentiation through cell-cell interactions.
Sugimoto M, Kondo M, Hirose M, Suzuki M, Mekada K, Abe T, Kiyonari H, Ogura A, Takagi N, Artzt K, Abe K., Cell Rep 2(5), 2012
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Sugimoto M, Kondo M, Hirose M, Suzuki M, Mekada K, Abe T, Kiyonari H, Ogura A, Takagi N, Artzt K, Abe K., Cell Rep 2(5), 2012
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Genetic correction of human induced pluripotent stem cells from patients with spinal muscular atrophy.
Corti S, Nizzardo M, Simone C, Falcone M, Nardini M, Ronchi D, Donadoni C, Salani S, Riboldi G, Magri F, Menozzi G, Bonaglia C, Rizzo F, Bresolin N, Comi GP., Sci Transl Med 4(165), 2012
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Corti S, Nizzardo M, Simone C, Falcone M, Nardini M, Ronchi D, Donadoni C, Salani S, Riboldi G, Magri F, Menozzi G, Bonaglia C, Rizzo F, Bresolin N, Comi GP., Sci Transl Med 4(165), 2012
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A computational prediction of structure and function of novel homologue of Arabidopsis thaliana Vps51/Vps67 subunit in Corchorus olitorius.
Zaman A, Fancy NN., Interdiscip Sci 4(4), 2012
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Zaman A, Fancy NN., Interdiscip Sci 4(4), 2012
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Reduced GABAergic inhibition explains cortical hyperexcitability in the wobbler mouse model of ALS.
Nieto-Gonzalez JL, Moser J, Lauritzen M, Schmitt-John T, Jensen K., Cereb Cortex 21(3), 2011
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Nieto-Gonzalez JL, Moser J, Lauritzen M, Schmitt-John T, Jensen K., Cereb Cortex 21(3), 2011
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VPS54 genetic analysis in ALS Italian cohort.
Corrado L, Gagliardi S, Carlomagno Y, Mennini T, Ticozzi N, Mazzini L, Silani V, Cereda C, D'Alfonso S., Eur J Neurol 18(4), 2011
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Corrado L, Gagliardi S, Carlomagno Y, Mennini T, Ticozzi N, Mazzini L, Silani V, Cereda C, D'Alfonso S., Eur J Neurol 18(4), 2011
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Transport according to GARP: receiving retrograde cargo at the trans-Golgi network.
Bonifacino JS, Hierro A., Trends Cell Biol 21(3), 2011
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Bonifacino JS, Hierro A., Trends Cell Biol 21(3), 2011
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Failure of acrosome formation and globozoospermia in the wobbler mouse, a Vps54 spontaneous recessive mutant.
Paiardi C, Pasini ME, Gioria M, Berruti G., Spermatogenesis 1(1), 2011
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Paiardi C, Pasini ME, Gioria M, Berruti G., Spermatogenesis 1(1), 2011
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Genetic rodent models of amyotrophic lateral sclerosis.
Van Den Bosch L., J Biomed Biotechnol 2011(), 2011
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Van Den Bosch L., J Biomed Biotechnol 2011(), 2011
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Proteomic analysis of muscle affected by motor neuron degeneration: the wobbler mouse model of amyotrophic lateral sclerosis.
Staunton L, Jockusch H, Ohlendieck K., Biochem Biophys Res Commun 406(4), 2011
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Staunton L, Jockusch H, Ohlendieck K., Biochem Biophys Res Commun 406(4), 2011
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Endosomal accumulation of APP in wobbler motor neurons reflects impaired vesicle trafficking: implications for human motor neuron disease.
Palmisano R, Golfi P, Heimann P, Shaw C, Troakes C, Schmitt-John T, Bartsch JW., BMC Neurosci 12(), 2011
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Palmisano R, Golfi P, Heimann P, Shaw C, Troakes C, Schmitt-John T, Bartsch JW., BMC Neurosci 12(), 2011
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Acrosome biogenesis: Revisiting old questions to yield new insights.
Berruti G, Paiardi C., Spermatogenesis 1(2), 2011
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Berruti G, Paiardi C., Spermatogenesis 1(2), 2011
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The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology.
Luo L, Hannemann M, Koenig S, Hegermann J, Ailion M, Cho MK, Sasidharan N, Zweckstetter M, Rensing SA, Eimer S., Mol Biol Cell 22(14), 2011
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Luo L, Hannemann M, Koenig S, Hegermann J, Ailion M, Cho MK, Sasidharan N, Zweckstetter M, Rensing SA, Eimer S., Mol Biol Cell 22(14), 2011
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Intracerebroventricular administration of human umbilical cord blood cells delays disease progression in two murine models of motor neuron degeneration.
Bigini P, Veglianese P, Andriolo G, Cova L, Grignaschi G, Caron I, Daleno C, Barbera S, Ottolina A, Calzarossa C, Lazzari L, Mennini T, Bendotti C, Silani V., Rejuvenation Res 14(6), 2011
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Bigini P, Veglianese P, Andriolo G, Cova L, Grignaschi G, Caron I, Daleno C, Barbera S, Ottolina A, Calzarossa C, Lazzari L, Mennini T, Bendotti C, Silani V., Rejuvenation Res 14(6), 2011
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Structure of Golgi transport proteins.
Kümmel D, Reinisch KM., Cold Spring Harb Perspect Biol 3(12), 2011
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Kümmel D, Reinisch KM., Cold Spring Harb Perspect Biol 3(12), 2011
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Molecular motor proteins and amyotrophic lateral sclerosis.
Soo KY, Farg M, Atkin JD., Int J Mol Sci 12(12), 2011
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Soo KY, Farg M, Atkin JD., Int J Mol Sci 12(12), 2011
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Stage dependent effects of progesterone on motoneurons and glial cells of wobbler mouse spinal cord degeneration.
Meyer M, Gonzalez Deniselle MC, Garay LI, Monachelli GG, Lima A, Roig P, Guennoun R, Schumacher M, De Nicola AF., Cell Mol Neurobiol 30(1), 2010
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Meyer M, Gonzalez Deniselle MC, Garay LI, Monachelli GG, Lima A, Roig P, Guennoun R, Schumacher M, De Nicola AF., Cell Mol Neurobiol 30(1), 2010
PMID: 19693665
Expression and localization of the deubiquitinating enzyme mUBPy in wobbler mouse testis during spermiogenesis.
Chianese R, Scarpa D, Berruti G, Cobellis G, Pierantoni R, Fasano S, Meccariello R., Gen Comp Endocrinol 166(2), 2010
PMID: 19800341
Chianese R, Scarpa D, Berruti G, Cobellis G, Pierantoni R, Fasano S, Meccariello R., Gen Comp Endocrinol 166(2), 2010
PMID: 19800341
USP8, a regulator of endosomal sorting, is involved in mouse acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules.
Berruti G, Ripolone M, Ceriani M., Biol Reprod 82(5), 2010
PMID: 20130268
Berruti G, Ripolone M, Ceriani M., Biol Reprod 82(5), 2010
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Spinal muscular atrophy: new and emerging insights from model mice.
Park GH, Kariya S, Monani UR., Curr Neurol Neurosci Rep 10(2), 2010
PMID: 20425235
Park GH, Kariya S, Monani UR., Curr Neurol Neurosci Rep 10(2), 2010
PMID: 20425235
Neuropathologic and biochemical changes during disease progression in liver X receptor beta-/- mice, a model of adult neuron disease.
Bigini P, Steffensen KR, Ferrario A, Diomede L, Ferrara G, Barbera S, Salzano S, Fumagalli E, Ghezzi P, Mennini T, Gustafsson JA., J Neuropathol Exp Neurol 69(6), 2010
PMID: 20467332
Bigini P, Steffensen KR, Ferrario A, Diomede L, Ferrara G, Barbera S, Salzano S, Fumagalli E, Ghezzi P, Mennini T, Gustafsson JA., J Neuropathol Exp Neurol 69(6), 2010
PMID: 20467332
Neural precursor-derived astrocytes of wobbler mice induce apoptotic death of motor neurons through reduced glutamate uptake.
Diana V, Ottolina A, Botti F, Fumagalli E, Calcagno E, De Paola M, Cagnotto A, Invernici G, Parati E, Curti D, Mennini T., Exp Neurol 225(1), 2010
PMID: 20558160
Diana V, Ottolina A, Botti F, Fumagalli E, Calcagno E, De Paola M, Cagnotto A, Invernici G, Parati E, Curti D, Mennini T., Exp Neurol 225(1), 2010
PMID: 20558160
Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex.
Pérez-Victoria FJ, Abascal-Palacios G, Tascón I, Kajava A, Magadán JG, Pioro EP, Bonifacino JS, Hierro A., Proc Natl Acad Sci U S A 107(29), 2010
PMID: 20615984
Pérez-Victoria FJ, Abascal-Palacios G, Tascón I, Kajava A, Magadán JG, Pioro EP, Bonifacino JS, Hierro A., Proc Natl Acad Sci U S A 107(29), 2010
PMID: 20615984
Structure of a C-terminal fragment of its Vps53 subunit suggests similarity of Golgi-associated retrograde protein (GARP) complex to a family of tethering complexes.
Vasan N, Hutagalung A, Novick P, Reinisch KM., Proc Natl Acad Sci U S A 107(32), 2010
PMID: 20660722
Vasan N, Hutagalung A, Novick P, Reinisch KM., Proc Natl Acad Sci U S A 107(32), 2010
PMID: 20660722
Ang2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complex.
Pérez-Victoria FJ, Schindler C, Magadán JG, Mardones GA, Delevoye C, Romao M, Raposo G, Bonifacino JS., Mol Biol Cell 21(19), 2010
PMID: 20685960
Pérez-Victoria FJ, Schindler C, Magadán JG, Mardones GA, Delevoye C, Romao M, Raposo G, Bonifacino JS., Mol Biol Cell 21(19), 2010
PMID: 20685960
Amyotrophic lateral sclerosis pathogenesis: a journey through the secretory pathway.
Nassif M, Matus S, Castillo K, Hetz C., Antioxid Redox Signal 13(12), 2010
PMID: 20560784
Nassif M, Matus S, Castillo K, Hetz C., Antioxid Redox Signal 13(12), 2010
PMID: 20560784
Tumor necrosis factor-alpha (TNF-alpha) regulates shedding of TNF-alpha receptor 1 by the metalloprotease-disintegrin ADAM8: evidence for a protease-regulated feedback loop in neuroprotection.
Bartsch JW, Wildeboer D, Koller G, Naus S, Rittger A, Moss ML, Minai Y, Jockusch H., J Neurosci 30(36), 2010
PMID: 20826683
Bartsch JW, Wildeboer D, Koller G, Naus S, Rittger A, Moss ML, Minai Y, Jockusch H., J Neurosci 30(36), 2010
PMID: 20826683
Exome sequencing reveals VCP mutations as a cause of familial ALS.
Johnson JO, Mandrioli J, Benatar M, Abramzon Y, Van Deerlin VM, Trojanowski JQ, Gibbs JR, Brunetti M, Gronka S, Wuu J, Ding J, McCluskey L, Martinez-Lage M, Falcone D, Hernandez DG, Arepalli S, Chong S, Schymick JC, Rothstein J, Landi F, Wang YD, Calvo A, Mora G, Sabatelli M, Monsurrò MR, Battistini S, Salvi F, Spataro R, Sola P, Borghero G, ITALSGEN Consortium, Galassi G, Scholz SW, Taylor JP, Restagno G, Chiò A, Traynor BJ., Neuron 68(5), 2010
PMID: 21145000
Johnson JO, Mandrioli J, Benatar M, Abramzon Y, Van Deerlin VM, Trojanowski JQ, Gibbs JR, Brunetti M, Gronka S, Wuu J, Ding J, McCluskey L, Martinez-Lage M, Falcone D, Hernandez DG, Arepalli S, Chong S, Schymick JC, Rothstein J, Landi F, Wang YD, Calvo A, Mora G, Sabatelli M, Monsurrò MR, Battistini S, Salvi F, Spataro R, Sola P, Borghero G, ITALSGEN Consortium, Galassi G, Scholz SW, Taylor JP, Restagno G, Chiò A, Traynor BJ., Neuron 68(5), 2010
PMID: 21145000
Mouse forward genetics in the study of the peripheral nervous system and human peripheral neuropathy.
Douglas DS, Popko B., Neurochem Res 34(1), 2009
PMID: 18481175
Douglas DS, Popko B., Neurochem Res 34(1), 2009
PMID: 18481175
Wobbler mice modeling motor neuron disease display elevated transactive response DNA binding protein.
Dennis JS, Citron BA., Neuroscience 158(2), 2009
PMID: 19013502
Dennis JS, Citron BA., Neuroscience 158(2), 2009
PMID: 19013502
The Vps33a gene regulates behavior and cerebellar Purkinje cell number.
Chintala S, Novak EK, Spernyak JA, Mazurchuk R, Torres G, Patel S, Busch K, Meeder BA, Horowitz JM, Vaughan MM, Swank RT., Brain Res 1266(), 2009
PMID: 19254700
Chintala S, Novak EK, Spernyak JA, Mazurchuk R, Torres G, Patel S, Busch K, Meeder BA, Horowitz JM, Vaughan MM, Swank RT., Brain Res 1266(), 2009
PMID: 19254700
Release of [3H]D-aspartate induced by K+-stimulation is increased in the cervical spinal cord of the wobbler mouse: a model of motor neuron disease.
Bonanno G, Fumagalli E, Milanese M, Zappettini S, Mennini T., Neurochem Int 55(5), 2009
PMID: 19576518
Bonanno G, Fumagalli E, Milanese M, Zappettini S, Mennini T., Neurochem Int 55(5), 2009
PMID: 19576518
Testicular gonadotropin-releasing hormone activity, progression of spermatogenesis, and sperm transport in vertebrates.
Pierantoni R, Cobellis G, Meccariello R, Cacciola G, Chianese R, Chioccarelli T, Fasano S., Ann N Y Acad Sci 1163(), 2009
PMID: 19456349
Pierantoni R, Cobellis G, Meccariello R, Cacciola G, Chianese R, Chioccarelli T, Fasano S., Ann N Y Acad Sci 1163(), 2009
PMID: 19456349
Experimental models for the study of neurodegeneration in amyotrophic lateral sclerosis.
Tovar-Y-Romo LB, Santa-Cruz LD, Tapia R., Mol Neurodegener 4(), 2009
PMID: 19619317
Tovar-Y-Romo LB, Santa-Cruz LD, Tapia R., Mol Neurodegener 4(), 2009
PMID: 19619317
Dual roles of the mammalian GARP complex in tethering and SNARE complex assembly at the trans-golgi network.
Pérez-Victoria FJ, Bonifacino JS., Mol Cell Biol 29(19), 2009
PMID: 19620288
Pérez-Victoria FJ, Bonifacino JS., Mol Cell Biol 29(19), 2009
PMID: 19620288
Atorvastatin treatment attenuates motor neuron degeneration in wobbler mice.
Iwamoto K, Yoshii Y, Ikeda K., Amyotroph Lateral Scler 10(5-6), 2009
PMID: 19922131
Iwamoto K, Yoshii Y, Ikeda K., Amyotroph Lateral Scler 10(5-6), 2009
PMID: 19922131
Recombinant human TNF-binding protein-1 (rhTBP-1) treatment delays both symptoms progression and motor neuron loss in the wobbler mouse.
Bigini P, Repici M, Cantarella G, Fumagalli E, Barbera S, Cagnotto A, De Luigi A, Tonelli R, Bernardini R, Borsello T, Mennini T., Neurobiol Dis 29(3), 2008
PMID: 18201889
Bigini P, Repici M, Cantarella G, Fumagalli E, Barbera S, Cagnotto A, De Luigi A, Tonelli R, Bernardini R, Borsello T, Mennini T., Neurobiol Dis 29(3), 2008
PMID: 18201889
Structure of msj-1 gene in mice and humans: a possible role in the regulation of male reproduction.
Meccariello R, Berruti G, Chianese R, De Santis R, Di Cunto F, Scarpa D, Cobellis G, Zucchetti I, Pierantoni R, Altruda F, Fasano S., Gen Comp Endocrinol 156(1), 2008
PMID: 18184612
Meccariello R, Berruti G, Chianese R, De Santis R, Di Cunto F, Scarpa D, Cobellis G, Zucchetti I, Pierantoni R, Altruda F, Fasano S., Gen Comp Endocrinol 156(1), 2008
PMID: 18184612
Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes.
Pérez-Victoria FJ, Mardones GA, Bonifacino JS., Mol Biol Cell 19(6), 2008
PMID: 18367545
Pérez-Victoria FJ, Mardones GA, Bonifacino JS., Mol Biol Cell 19(6), 2008
PMID: 18367545
Amyotrophic lateral sclerosis: Protein chaperone dysfunction revealed by proteomic studies of animal models.
Jain MR, Ge WW, Elkabes S, Li H., Proteomics - Clinical Applications 2(5), 2008
PMID: C1913
Jain MR, Ge WW, Elkabes S, Li H., Proteomics - Clinical Applications 2(5), 2008
PMID: C1913
Amyotrophic lateral sclerosis: Protein chaperone dysfunction revealed by proteomic studies of animal models.
Jain MR, Ge WW, Elkabes S, Li H., Proteomics Clin Appl 2(5), 2008
PMID: 19578526
Jain MR, Ge WW, Elkabes S, Li H., Proteomics Clin Appl 2(5), 2008
PMID: 19578526
Differential sensitivity of mouse strains to an N-alkylated imino sugar: glycosphingolipid metabolism and acrosome formation.
van der Spoel AC, Mott R, Platt FM., Pharmacogenomics 9(6), 2008
PMID: 18518850
van der Spoel AC, Mott R, Platt FM., Pharmacogenomics 9(6), 2008
PMID: 18518850
Evaluation of the Golgi trafficking protein VPS54 (wobbler) as a candidate for ALS.
Meisler MH, Russ C, Montgomery KT, Greenway M, Ennis S, Hardiman O, Figlewicz DA, Quenneville NR, Conibear E, Brown RH., Amyotroph Lateral Scler 9(3), 2008
PMID: 18574757
Meisler MH, Russ C, Montgomery KT, Greenway M, Ennis S, Hardiman O, Figlewicz DA, Quenneville NR, Conibear E, Brown RH., Amyotroph Lateral Scler 9(3), 2008
PMID: 18574757
Hypertonia-associated protein Trak1 is a novel regulator of endosome-to-lysosome trafficking.
Webber E, Li L, Chin LS., J Mol Biol 382(3), 2008
PMID: 18675823
Webber E, Li L, Chin LS., J Mol Biol 382(3), 2008
PMID: 18675823
Carbamylated erythropoietin to treat neuronal injury: new development strategies.
Lapchak PA., Expert Opin Investig Drugs 17(8), 2008
PMID: 18616414
Lapchak PA., Expert Opin Investig Drugs 17(8), 2008
PMID: 18616414
Progesterone modulates brain-derived neurotrophic factor and choline acetyltransferase in degenerating Wobbler motoneurons.
Gonzalez Deniselle MC, Garay L, Gonzalez S, Saravia F, Labombarda F, Guennoun R, Schumacher M, De Nicola AF., Exp Neurol 203(2), 2007
PMID: 17052708
Gonzalez Deniselle MC, Garay L, Gonzalez S, Saravia F, Labombarda F, Guennoun R, Schumacher M, De Nicola AF., Exp Neurol 203(2), 2007
PMID: 17052708
Non-developmentally programmed cell death in Caenorhabditis elegans.
Kourtis N, Tavernarakis N., Semin Cancer Biol 17(2), 2007
PMID: 17196824
Kourtis N, Tavernarakis N., Semin Cancer Biol 17(2), 2007
PMID: 17196824
In vivo distribution and localization of chorein.
Kurano Y, Nakamura M, Ichiba M, Matsuda M, Mizuno E, Kato M, Agemura A, Izumo S, Sano A., Biochem Biophys Res Commun 353(2), 2007
PMID: 17188237
Kurano Y, Nakamura M, Ichiba M, Matsuda M, Mizuno E, Kato M, Agemura A, Izumo S, Sano A., Biochem Biophys Res Commun 353(2), 2007
PMID: 17188237
UBPy/MSJ-1 system during male germ cell progression in the frog, Rana esculenta.
Meccariello R, Chianese R, Scarpa D, Berruti G, Cobellis G, Pierantoni R, Fasano S., Gen Comp Endocrinol 153(1-3), 2007
PMID: 17187787
Meccariello R, Chianese R, Scarpa D, Berruti G, Cobellis G, Pierantoni R, Fasano S., Gen Comp Endocrinol 153(1-3), 2007
PMID: 17187787
Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking.
Kim BY, Olzmann JA, Barsh GS, Chin LS, Li L., Mol Biol Cell 18(4), 2007
PMID: 17229889
Kim BY, Olzmann JA, Barsh GS, Chin LS, Li L., Mol Biol Cell 18(4), 2007
PMID: 17229889
Neuronal death: where does the end begin?
Conforti L, Adalbert R, Coleman MP., Trends Neurosci 30(4), 2007
PMID: 17339056
Conforti L, Adalbert R, Coleman MP., Trends Neurosci 30(4), 2007
PMID: 17339056
Transcription factor p53 in degenerating spinal cords.
Eve DJ, Dennis JS, Citron BA., Brain Res 1150(), 2007
PMID: 17434459
Eve DJ, Dennis JS, Citron BA., Brain Res 1150(), 2007
PMID: 17434459
A missense mutation in the 3-ketodihydrosphingosine reductase FVT1 as candidate causal mutation for bovine spinal muscular atrophy.
Krebs S, Medugorac I, Röther S, Strässer K, Förster M., Proc Natl Acad Sci U S A 104(16), 2007
PMID: 17420465
Krebs S, Medugorac I, Röther S, Strässer K, Förster M., Proc Natl Acad Sci U S A 104(16), 2007
PMID: 17420465
Large-scale pathways-based association study in amyotrophic lateral sclerosis.
Kasperaviciute D, Weale ME, Shianna KV, Banks GT, Simpson CL, Hansen VK, Turner MR, Shaw CE, Al-Chalabi A, Pall HS, Goodall EF, Morrison KE, Orrell RW, Beck M, Jablonka S, Sendtner M, Brockington A, Ince PG, Hartley J, Nixon H, Shaw PJ, Schiavo G, Wood NW, Goldstein DB, Fisher EM., Brain 130(pt 9), 2007
PMID: 17439985
Kasperaviciute D, Weale ME, Shianna KV, Banks GT, Simpson CL, Hansen VK, Turner MR, Shaw CE, Al-Chalabi A, Pall HS, Goodall EF, Morrison KE, Orrell RW, Beck M, Jablonka S, Sendtner M, Brockington A, Ince PG, Hartley J, Nixon H, Shaw PJ, Schiavo G, Wood NW, Goldstein DB, Fisher EM., Brain 130(pt 9), 2007
PMID: 17439985
Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J.
Chow CY, Zhang Y, Dowling JJ, Jin N, Adamska M, Shiga K, Szigeti K, Shy ME, Li J, Zhang X, Lupski JR, Weisman LS, Meisler MH., Nature 448(7149), 2007
PMID: 17572665
Chow CY, Zhang Y, Dowling JJ, Jin N, Adamska M, Shiga K, Szigeti K, Shy ME, Li J, Zhang X, Lupski JR, Weisman LS, Meisler MH., Nature 448(7149), 2007
PMID: 17572665
Progesterone: therapeutic opportunities for neuroprotection and myelin repair.
Schumacher M, Guennoun R, Stein DG, De Nicola AF., Pharmacol Ther 116(1), 2007
PMID: 17659348
Schumacher M, Guennoun R, Stein DG, De Nicola AF., Pharmacol Ther 116(1), 2007
PMID: 17659348
Alsin and the molecular pathways of amyotrophic lateral sclerosis.
Chandran J, Ding J, Cai H., Mol Neurobiol 36(3), 2007
PMID: 17955197
Chandran J, Ding J, Cai H., Mol Neurobiol 36(3), 2007
PMID: 17955197
Snc1p v-SNARE transport to the prospore membrane during yeast sporulation is dependent on endosomal retrieval pathways.
Morishita M, Mendonsa R, Wright J, Engebrecht J., Traffic 8(9), 2007
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Morishita M, Mendonsa R, Wright J, Engebrecht J., Traffic 8(9), 2007
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Defective axonal transport in motor neuron disease.
El-Kadi AM, Soura V, Hafezparast M., J Neurosci Res 85(12), 2007
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El-Kadi AM, Soura V, Hafezparast M., J Neurosci Res 85(12), 2007
PMID: 17265455
Lack of caspase-dependent apoptosis in spinal motor neurons of the wobbler mouse.
Bigini P, Atzori C, Fumagalli E, Cagnotto A, Barbera S, Migheli A, Mennini T., Neurosci Lett 426(2), 2007
PMID: 17890007
Bigini P, Atzori C, Fumagalli E, Cagnotto A, Barbera S, Migheli A, Mennini T., Neurosci Lett 426(2), 2007
PMID: 17890007
The molecular genetics and neuropathology of frontotemporal lobar degeneration: recent developments.
Mackenzie IR, Rademakers R., Neurogenetics 8(4), 2007
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Mackenzie IR, Rademakers R., Neurogenetics 8(4), 2007
PMID: 17805587
Heterogeneity in motoneuron disease.
Lambrechts D, Robberecht W, Carmeliet P., Trends Neurosci 30(10), 2007
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Lambrechts D, Robberecht W, Carmeliet P., Trends Neurosci 30(10), 2007
PMID: 17825438
Cell therapy and stem cells in animal models of motor neuron disorders.
Hedlund E, Hefferan MP, Marsala M, Isacson O., Eur J Neurosci 26(7), 2007
PMID: 17897390
Hedlund E, Hefferan MP, Marsala M, Isacson O., Eur J Neurosci 26(7), 2007
PMID: 17897390
Axonal degeneration in motor neuron disease.
Fischer LR, Glass JD., Neurodegener Dis 4(6), 2007
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Fischer LR, Glass JD., Neurodegener Dis 4(6), 2007
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Neurotrophin and Trk-mediated signaling in the neuromuscular system.
Pitts EV, Potluri S, Hess DM, Balice-Gordon RJ., Int Anesthesiol Clin 44(2), 2006
PMID: 16849956
Pitts EV, Potluri S, Hess DM, Balice-Gordon RJ., Int Anesthesiol Clin 44(2), 2006
PMID: 16849956
Targets in ALS: designing multidrug therapies.
Carrì MT, Grignaschi G, Bendotti C., Trends Pharmacol Sci 27(5), 2006
PMID: 16690390
Carrì MT, Grignaschi G, Bendotti C., Trends Pharmacol Sci 27(5), 2006
PMID: 16690390
Nonhematopoietic erythropoietin derivatives prevent motoneuron degeneration in vitro and in vivo.
Mennini T, De Paola M, Bigini P, Mastrotto C, Fumagalli E, Barbera S, Mengozzi M, Viviani B, Corsini E, Marinovich M, Torup L, Van Beek J, Leist M, Brines M, Cerami A, Ghezzi P., Mol Med 12(7-8), 2006
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