Coarse-grained lattice model for molecular recognition

Behringer H, Degenhard A, Schmid F (2006)
Physical Review Letters 97(12): 128101.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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DOI
Autor*in
Behringer, Hans; Degenhard, Andreas; Schmid, Friederike
Einrichtung
SFB 613 Physik von Einzelmolekülprozessen/mol.Erkennung in organ.Sys.
Fakultät für Physik
Abstract / Bemerkung
We present a simple model which allows us to investigate the equilibrium aspects of molecular recognition between rigid biomolecules on a generic level. Using a two-stage approach, which consists of a design and a testing step, the role of cooperativity and of varying bond strength in molecular recognition is investigated. Cooperativity is found to enhance selectivity. In complexes which require a high binding flexibility, a small number of strong bonds seems to be favored compared to a situation with many but weak bonds.
Erscheinungsjahr
2006
Zeitschriftentitel
Physical Review Letters
Band
97
Ausgabe
12
Art.-Nr.
128101
ISSN
0031-9007
Page URI
https://pub.uni-bielefeld.de/record/1597777

Zitieren

Behringer H, Degenhard A, Schmid F. Coarse-grained lattice model for molecular recognition. Physical Review Letters. 2006;97(12): 128101.
Behringer, H., Degenhard, A., & Schmid, F. (2006). Coarse-grained lattice model for molecular recognition. Physical Review Letters, 97(12), 128101. https://doi.org/10.1103/PhysRevLett.97.128101
Behringer, Hans, Degenhard, Andreas, and Schmid, Friederike. 2006. “Coarse-grained lattice model for molecular recognition”. Physical Review Letters 97 (12): 128101.
Behringer, H., Degenhard, A., and Schmid, F. (2006). Coarse-grained lattice model for molecular recognition. Physical Review Letters 97:128101.
Behringer, H., Degenhard, A., & Schmid, F., 2006. Coarse-grained lattice model for molecular recognition. Physical Review Letters, 97(12): 128101.
H. Behringer, A. Degenhard, and F. Schmid, “Coarse-grained lattice model for molecular recognition”, Physical Review Letters, vol. 97, 2006, : 128101.
Behringer, H., Degenhard, A., Schmid, F.: Coarse-grained lattice model for molecular recognition. Physical Review Letters. 97, : 128101 (2006).
Behringer, Hans, Degenhard, Andreas, and Schmid, Friederike. “Coarse-grained lattice model for molecular recognition”. Physical Review Letters 97.12 (2006): 128101.

11 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

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