{"publication_identifier":{"eissn":["1861-9541"],"issn":["1001-6538"]},"date_created":"2010-04-28T12:18:44Z","publisher":"SCIENCE CHINA PRESS","department":[{"_id":"441929"}],"external_id":{"isi":["000241849200008"]},"type_old":["journalArticle","journalarticle","journal_article"],"language":[{"iso":"eng"}],"status":"public","abstract":[{"lang":"eng","text":"Gene expression profiles of a Sinorhizobium meliloti 1021 nifA mutant and wild type nodule bacteria were compared using whole genome microarrays. The results revealed a large scale alteration of gene expression (601 genes) in the nifA minus background. The loss of NifA altered the expression of many functional groups of genes (macromolecular metabolism, TCA cycle and respiration, nodulation and nitrogen fixation) and may lead to quite different life stages of the nodule bacteria. Upregulation of fixK and its associated genes was observed in the nifA mutant nodule bacteria. Additional quantitative real-time PCR experiments revealed that the transcript levels of fixLJ were significantly upshifted in the nifA mutant nodule bacteria. Putative NifA binding sites were predicted by a statistical method in the upstream sequences of 13 differentially regulated genes from the nifA transcriptome."}],"title":"Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background","intvolume":" 51","quality_controlled":"1","volume":51,"page":"2079-2086","issue":"17","author":[{"first_name":"Zhexian","last_name":"Tian","full_name":"Tian, Zhexian"},{"full_name":"Zou, Huasong","last_name":"Zou","first_name":"Huasong"},{"last_name":"Li","first_name":"Jian","full_name":"Li, Jian"},{"last_name":"Zhang","first_name":"Yuantao","full_name":"Zhang, Yuantao"},{"last_name":"Liu","first_name":"Ying","full_name":"Liu, Ying"},{"full_name":"Yu, Guanqiao","last_name":"Yu","first_name":"Guanqiao"},{"first_name":"Jiabi","last_name":"Zhu","full_name":"Zhu, Jiabi"},{"full_name":"Ruberg, Silvia","last_name":"Ruberg","first_name":"Silvia"},{"first_name":"Anke","last_name":"Becker","full_name":"Becker, Anke"},{"first_name":"Yiping","last_name":"Wang","full_name":"Wang, Yiping"}],"type":"journal_article","isi":1,"citation":{"bio1":"Tian Z, Zou H, Li J, Zhang Y, Liu Y, Yu G, Zhu J, Ruberg S, Becker A, Wang Y (2006) <br />Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background.<br />CHINESE SCIENCE BULLETIN 51(17): 2079-2086.","frontiers":"Tian, Z., Zou, H., Li, J., Zhang, Y., Liu, Y., Yu, G., Zhu, J., Ruberg, S., Becker, A., and Wang, Y. (2006). Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background. <em>CHINESE SCIENCE BULLETIN</em> 51, 2079-2086.","chicago":"<div style=\"text-indent:-25px; padding-left:25px;padding-bottom:0px;\">Tian, Zhexian, Zou, Huasong, Li, Jian, Zhang, Yuantao, Liu, Ying, Yu, Guanqiao, Zhu, Jiabi, Ruberg, Silvia, Becker, Anke, and Wang, Yiping. 2006. “Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background”. <em>CHINESE SCIENCE BULLETIN</em> 51 (17): 2079-2086.</div>","apa":"Tian, Z., Zou, H., Li, J., Zhang, Y., Liu, Y., Yu, G., Zhu, J., et al. (2006). Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background. <em>CHINESE SCIENCE BULLETIN</em>, <em>51</em>(17), 2079-2086. <a href=\"https://doi.org/10.1007/s11434-006-2092-2\" target=\"_blank\">https://doi.org/10.1007/s11434-006-2092-2</a>","default":"Tian Z, Zou H, Li J, Zhang Y, Liu Y, Yu G, Zhu J, Ruberg S, Becker A, Wang Y (2006) <br /><em>CHINESE SCIENCE BULLETIN</em> 51(17): 2079-2086.","harvard1":"Tian, Z., et al., 2006. Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background. <em>CHINESE SCIENCE BULLETIN</em>, 51(17), p 2079-2086.","wels":"Tian, Z.; Zou, H.; Li, J.; Zhang, Y.; Liu, Y.; Yu, G.; Zhu, J.; Ruberg, S.; Becker, A.; Wang, Y. (2006): Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background <em>CHINESE SCIENCE BULLETIN</em>,51:(17): 2079-2086.","dgps":"<div style=\"text-indent:-25px; padding-left:25px;padding-bottom:0px;\">Tian, Z., Zou, H., Li, J., Zhang, Y., Liu, Y., Yu, G., Zhu, J., Ruberg, S., Becker, A. & Wang, Y. (2006). Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background. <em>CHINESE SCIENCE BULLETIN</em>, <em>51</em>(17), 2079-2086. SCIENCE CHINA PRESS. doi:10.1007/s11434-006-2092-2.</div>","angewandte-chemie":"Z. Tian, H. Zou, J. Li, Y. Zhang, Y. Liu, G. Yu, J. Zhu, S. Ruberg, A. Becker, and Y. Wang, “Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background”, <em>CHINESE SCIENCE BULLETIN</em>, <strong>2006</strong>, <em>51</em>, 2079-2086.","apa_indent":"<div style=\"text-indent:-25px; padding-left:25px;padding-bottom:0px;\">Tian, Z., Zou, H., Li, J., Zhang, Y., Liu, Y., Yu, G., Zhu, J., et al. (2006). Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background. <em>CHINESE SCIENCE BULLETIN</em>, <em>51</em>(17), 2079-2086. <a href=\"https://doi.org/10.1007/s11434-006-2092-2\" target=\"_blank\">https://doi.org/10.1007/s11434-006-2092-2</a></div>","ieee":" Z. Tian, et al., “Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background”, <em>CHINESE SCIENCE BULLETIN</em>, vol. 51, 2006, pp. 2079-2086.","ama":"Tian Z, Zou H, Li J, et al. Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background. <em>CHINESE SCIENCE BULLETIN</em>. 2006;51(17):2079-2086.","lncs":" Tian, Z., Zou, H., Li, J., Zhang, Y., Liu, Y., Yu, G., Zhu, J., Ruberg, S., Becker, A., Wang, Y.: Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background. CHINESE SCIENCE BULLETIN. 51, 2079-2086 (2006).","mla":"Tian, Zhexian, Zou, Huasong, Li, Jian, Zhang, Yuantao, Liu, Ying, Yu, Guanqiao, Zhu, Jiabi, Ruberg, Silvia, Becker, Anke, and Wang, Yiping. “Transcriptome analysis of Sinorhizobium meliloti nodule bacteria in nifA mutant background”. <em>CHINESE SCIENCE BULLETIN</em> 51.17 (2006): 2079-2086."},"publication_status":"published","_id":"1597223","keyword":["transcriptorne","FixJ","NifA","nodule bacteria"],"publication":"CHINESE SCIENCE BULLETIN","year":"2006","date_updated":"2018-07-24T12:58:52Z","doi":"10.1007/s11434-006-2092-2","first_contributor":"Tian, Zhexian","article_type":"original"}