Developing and analyzing idealized models for molecular recognition

Behringer H, Bogner T, Polotsky A, Degenhard A, Schmid F (2007)
Journal of Biotechnology 129(2): 268-278.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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Autor/in
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Abstract / Bemerkung
We study equilibrium aspects of molecular recognition of two biomolecules using idealized model systems and methods from statistical physics. Starting from the basic experimental findings we demonstrate exemplarily how an idealized coarse-grained model for the investigation of molecular recognition of two biomolecules can be developed. In addition we provide details regarding two model systems for the recognition of a flexible and a rigid biomolecule respectively, the latter taking into account conformational changes. We focus particularly on the interplay and influence of the correlations of the residue distributions of the biomolecules on the recognition process. (c) 2007 Elsevier B.V. All rights reserved.
Stichworte
model reduction; coarse-graining; molecular recognition; biophysics
Erscheinungsjahr
2007
Zeitschriftentitel
Journal of Biotechnology
Band
129
Ausgabe
2
Seite(n)
268-278
ISSN
0168-1656
Page URI
https://pub.uni-bielefeld.de/record/1594013

Zitieren

Behringer H, Bogner T, Polotsky A, Degenhard A, Schmid F. Developing and analyzing idealized models for molecular recognition. Journal of Biotechnology. 2007;129(2):268-278.
Behringer, H., Bogner, T., Polotsky, A., Degenhard, A., & Schmid, F. (2007). Developing and analyzing idealized models for molecular recognition. Journal of Biotechnology, 129(2), 268-278. doi:10.1016/j.jbiotec.2007.01.035
Behringer, H., Bogner, T., Polotsky, A., Degenhard, A., and Schmid, F. (2007). Developing and analyzing idealized models for molecular recognition. Journal of Biotechnology 129, 268-278.
Behringer, H., et al., 2007. Developing and analyzing idealized models for molecular recognition. Journal of Biotechnology, 129(2), p 268-278.
H. Behringer, et al., “Developing and analyzing idealized models for molecular recognition”, Journal of Biotechnology, vol. 129, 2007, pp. 268-278.
Behringer, H., Bogner, T., Polotsky, A., Degenhard, A., Schmid, F.: Developing and analyzing idealized models for molecular recognition. Journal of Biotechnology. 129, 268-278 (2007).
Behringer, Hans, Bogner, Thorsten, Polotsky, Alexey, Degenhard, Andreas, and Schmid, Friederike. “Developing and analyzing idealized models for molecular recognition”. Journal of Biotechnology 129.2 (2007): 268-278.

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PMID: 17368607
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