Steroids in chicken egg yolk: Metabolism and uptake during early embryonic development

von Engelhardt N, Henriksen R, Groothuis TGG (2009)
GENERAL AND COMPARATIVE ENDOCRINOLOGY 163(1-2): 175-183.

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Konferenzbeitrag | Veröffentlicht | Englisch
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Abstract / Bemerkung
Effects of maternal hormones may adaptively adjust offspring development to prevailing conditions. However, Darwinian fitness of parents is maximized by investing in more than one offspring while each individual offspring benefits from receiving maximal investment. The control of mother and offspring over hormone-mediated maternal effects is thought to play a key role in the outcome of parent-offspring conflict, but these control mechanisms have hardly been studied. We investigated the potential embryonic control by analysing the changes in distribution and metabolism of steroid hormones in the egg during the first 6 days of incubation using injections of radiolabelled testosterone and corticosterone in freshly laid eggs. After I day of incubation the highest amount of radioactivity was concentrated in a small area at the top of the yolk. This challenges the use of hormones in oil as mimicking natural exposure. During incubation radioactivity spread within the egg with highest concentrations in yolk and yolk sac and lower concentrations in albumen, embryo, allantois, and amnion. Steroids were metabolised to other unconjugated and conjugated steroids, perhaps facilitating embryonic steroid uptake. Our study shows that the injected radiolabel is metabolised in the egg and taken up by the embryo, giving the embryo potential control over the effects of maternal hormones and thereby limiting maternal control over the outcome of hormone-mediated maternal effects. (C) 2009 Elsevier Inc. All rights reserved.
Erscheinungsjahr
Band
163
Zeitschriftennummer
1-2
Seite
175-183
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von Engelhardt N, Henriksen R, Groothuis TGG. Steroids in chicken egg yolk: Metabolism and uptake during early embryonic development. GENERAL AND COMPARATIVE ENDOCRINOLOGY. 2009;163(1-2):175-183.
von Engelhardt, N., Henriksen, R., & Groothuis, T. G. G. (2009). Steroids in chicken egg yolk: Metabolism and uptake during early embryonic development. GENERAL AND COMPARATIVE ENDOCRINOLOGY, 163(1-2), 175-183. doi:10.1016/j.ygcen.2009.04.004
von Engelhardt, N., Henriksen, R., and Groothuis, T. G. G. (2009). Steroids in chicken egg yolk: Metabolism and uptake during early embryonic development. GENERAL AND COMPARATIVE ENDOCRINOLOGY 163, 175-183.
von Engelhardt, N., Henriksen, R., & Groothuis, T.G.G., 2009. Steroids in chicken egg yolk: Metabolism and uptake during early embryonic development. GENERAL AND COMPARATIVE ENDOCRINOLOGY, 163(1-2), p 175-183.
N. von Engelhardt, R. Henriksen, and T.G.G. Groothuis, “Steroids in chicken egg yolk: Metabolism and uptake during early embryonic development”, GENERAL AND COMPARATIVE ENDOCRINOLOGY, vol. 163, 2009, pp. 175-183.
von Engelhardt, N., Henriksen, R., Groothuis, T.G.G.: Steroids in chicken egg yolk: Metabolism and uptake during early embryonic development. GENERAL AND COMPARATIVE ENDOCRINOLOGY. 163, 175-183 (2009).
von Engelhardt, Nikolaus, Henriksen, Rie, and Groothuis, Ton G. G. “Steroids in chicken egg yolk: Metabolism and uptake during early embryonic development”. GENERAL AND COMPARATIVE ENDOCRINOLOGY 163.1-2 (2009): 175-183.

33 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Gonadal steroid levels in rock pigeon eggs do not represent adequately maternal allocation.
Kumar N, van Faassen M, de Vries B, Kema I, Gahr M, Groothuis TGG., Sci Rep 8(1), 2018
PMID: 30046065
Parent-embryo acoustic communication: a specialised heat vocalisation allowing embryonic eavesdropping.
Mariette MM, Pessato A, Buttemer WA, McKechnie AE, Udino E, Collins RN, Meillère A, Bennett ATD, Buchanan KL., Sci Rep 8(1), 2018
PMID: 30532029
Contrasting effects of increased yolk testosterone content on development and oxidative status in gull embryos.
Parolini M, Romano A, Possenti CD, Caprioli M, Rubolini D, Saino N., J Exp Biol 220(pt 4), 2017
PMID: 28202650
Yolk testosterone affects growth and promotes individual-level consistency in behavioral lateralization of yellow-legged gull chicks.
Possenti CD, Romano A, Caprioli M, Rubolini D, Spiezio C, Saino N, Parolini M., Horm Behav 80(), 2016
PMID: 26836770
Pre- and Postnatal Effects of Corticosterone on Fitness-Related Traits and the Timing of Endogenous Corticosterone Production in a Songbird.
Strange MS, Bowden RM, Thompson CF, Sakaluk SK., J Exp Zool A Ecol Genet Physiol 325(6), 2016
PMID: 27279255
Acute embryonic exposure to corticosterone alters physiology, behaviour and growth in nestlings of a wild passerine.
Tilgar V, Mägi M, Lind M, Lodjak J, Moks K, Mänd R., Horm Behav 84(), 2016
PMID: 27374762
Use of LC-MS-MS as an alternative to currently available immunoassay methods to quantitate corticosterone in egg yolk and albumen.
De Baere S, Rosendahl Larsen T, Devreese M, De Backer P, De Neve L, Fairhurst G, Lens L, Croubels S., Anal Bioanal Chem 407(15), 2015
PMID: 25407427
Immune activation generates corticosterone-mediated terminal reproductive investment in a wild bird.
Bowers EK, Bowden RM, Sakaluk SK, Thompson CF., Am Nat 185(6), 2015
PMID: 25996862
Introducing biological realism into the study of developmental plasticity in behaviour.
Groothuis TGG, Taborsky B., Front Zool 12 Suppl 1(), 2015
PMID: 26816523
Sulfonation of maternal steroids is a conserved metabolic pathway in vertebrates.
Paitz RT, Bowden RM., Integr Comp Biol 53(6), 2013
PMID: 23620254
In ovo inhibition of steroid metabolism by bisphenol-A as a potential mechanism of endocrine disruption.
Clairardin SG, Paitz RT, Bowden RM., Proc Biol Sci 280(1769), 2013
PMID: 24004940
Prenatal exposure to testosterone impairs oxidative damage repair efficiency in the domestic chicken (Gallus gallus).
Treidel LA, Whitley BN, Benowitz-Fredericks ZM, Haussmann MF., Biol Lett 9(5), 2013
PMID: 24046877
Yolk testosterone levels and offspring phenotype correlate with parental age in a precocial bird.
Guibert F, Richard-Yris MA, Lumineau S, Kotrschal K, Möstl E, Houdelier C., Physiol Behav 105(2), 2012
PMID: 21871470
Embryonic modulation of maternal steroids in European starlings (Sturnus vulgaris).
Paitz RT, Bowden RM, Casto JM., Proc Biol Sci 278(1702), 2011
PMID: 20667883
Effects of egg testosterone on female mate choice and male sexual behavior in the pheasant.
Bonisoli-Alquati A, Matteo A, Ambrosini R, Rubolini D, Romano M, Caprioli M, Dessì-Fulgheri F, Baratti M, Saino N., Horm Behav 59(1), 2011
PMID: 21029735
Beyond maternal effects in birds: responses of the embryo to the environment.
Reed WL, Clark ME., Integr Comp Biol 51(1), 2011
PMID: 21624931
A place to hide in the home-cage decreases yolk androgen levels and offspring emotional reactivity in Japanese quail.
Guesdon V, Bertin A, Houdelier C, Lumineau S, Formanek L, Kotrschal K, Möstl E, Richard-Yris MA., PLoS One 6(9), 2011
PMID: 21980338
A polymorphism in the oestrogen receptor gene explains covariance between digit ratio and mating behaviour.
Forstmeier W, Mueller JC, Kempenaers B., Proc Biol Sci 277(1698), 2010
PMID: 20534613
Social instability in laying quail: consequences on yolk steroids and offspring's phenotype.
Guibert F, Richard-Yris MA, Lumineau S, Kotrschal K, Guémené D, Bertin A, Möstl E, Houdelier C., PLoS One 5(11), 2010
PMID: 21124926

56 References

Daten bereitgestellt von Europe PubMed Central.

Sites of estrogen receptor and aromatase expression in the chicken embryo.
Andrews JE, Smith CA, Sinclair AH., Gen. Comp. Endocrinol. 108(2), 1997
PMID: 9356214
Steroid conversion by oocytes and early embryos of Salmo gairdneri
Antila, Annales Zoologici Fennici 21(), 1984
Early steroid metabolism by chick blastoderm in vitro.
Antila E, Leikola A, Tahka S., Steroids 43(3), 1984
PMID: 6240803
Regulatory effects of 5 beta-reduced steroids.
Aragones A, Gonzalez CB, Spinedi NC, Lantos CP., J. Steroid Biochem. Mol. Biol. 39(2), 1991
PMID: 1888686
Neurosteroids: a new brain function?
Baulieu EE, Robel P., J. Steroid Biochem. Mol. Biol. 37(3), 1990
PMID: 2257243
Developmental endocrinology of the reproductive axis in the chicken embryo.
Bruggeman V, Van As P, Decuypere E., Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 131(4), 2002
PMID: 11897195
Sexual versus individual differentiation: the controversial role of avian maternal hormones.
Carere C, Balthazart J., Trends Endocrinol. Metab. 18(2), 2007
PMID: 17276694
Endocrinology of teleost reproduction: a testicular steroid pheromone in the black goby, Gobius jozo L
Colombo, Bolletino Zoologico 47(), 1980
Neurosteroids: biosynthesis and function of these novel neuromodulators.
Compagnone NA, Mellon SH., Front Neuroendocrinol 21(1), 2000
PMID: 10662535
Biology and function of the reversible sulfation pathway catalysed by human sulfotransferases and sulfatases.
Coughtrie MW, Sharp S, Maxwell K, Innes NP., Chem. Biol. Interact. 109(1-3), 1998
PMID: 9566730
Anti-angiogenesis by steroids without glucocorticoid or mineralocorticoid activity in the presence of heparin
Crum, Journal of Cell Biology 99(), 1984
Maternal androgens in egg yolks: relation with sex, incubation time and embryonic growth.
Eising CM, Muller W, Dijkstra C, Groothuis TG., Gen. Comp. Endocrinol. 132(2), 2003
PMID: 12812771
Stress responses in avian embryos
Epple, American Zoologist 37(), 1997
Angiostatic steroids. Method of discovery and mechanism of action.
Folkman J, Ingber DE., Ann. Surg. 206(3), 1987
PMID: 2443088
Golden eggs: maternal manipulation of offspring phenotype by egg androgen in birds
Gil, Ardeola 50(), 2003
Hormones in avian eggs: physiology, ecology and behavior
Gil, Advances in the Study of Behavior 38(), 2008
In vivo estrogen synthesis by the developing chicken (Gallus gallus) embryo.
Gill DV, Robertson HA, Betz TW., Gen. Comp. Endocrinol. 49(2), 1983
PMID: 6840514
Maternal hormones as a tool to adjust offspring phenotype in avian species.
Groothuis TG, Muller W, von Engelhardt N, Carere C, Eising C., Neurosci Biobehav Rev 29(2), 2005
PMID: 15811503
Hormone-mediated maternal effects in birds: mechanisms matter but what do we know of them?
Groothuis TG, Schwabl H., Philos. Trans. R. Soc. Lond., B, Biol. Sci. 363(1497), 2008
PMID: 18048291
Investigating maternal hormones in avian eggs: measurement, manipulation, and interpretation.
Groothuis TG, von Engelhardt N., Ann. N. Y. Acad. Sci. 1046(), 2005
PMID: 16055850
Progesterone receptors in hypothalamus and pituitary during the embryonic development of the chick: regulation by sex steroid hormones
Guennon, Developmental Brain Research 37(), 1987
Métabolisme de la déhydroépiandrostérone et de la testostérone radioactives par les gonades mâles intersexuées de l’embryon de poulet cultivées in vitro
Haffen, Comptes Rendus Hebdomadaires Des Seances De L’ Academie Des Sciences Serie D 264(), 1967
Genetic conflicts in human pregnancy.
Haig D., Q Rev Biol 68(4), 1993
PMID: 8115596
Placental hormones, genomic imprinting, and maternal–fetal communication
Haig, Journal of Evolutionary Biology 9(), 1996
Detection in bovine adrenal cortex of a lipoidal substance that yields pregnenolone upon treatment with alkali.
Hochberg RB, Bandy L, Ponticorvo L, Lieberman S., Proc. Natl. Acad. Sci. U.S.A. 74(3), 1977
PMID: 15261
Steroidal fatty acid esters.
Hochberg RB, Pahuja SL, Zielinski JE, Larner JM., J. Steroid Biochem. Mol. Biol. 40(4-6), 1991
PMID: 1835647
Stimulation of hemoglobin synthesis in chick blastoderms by certain 5beta androstane and 5beta pregnane steroids.
Levere RD, Kappas A, Granick S., Proc. Natl. Acad. Sci. U.S.A. 58(3), 1967
PMID: 5233854
Conjugation and transfer of fetal-placental steroid hormones.
Levitz M., J. Clin. Endocrinol. Metab. 26(7), 1966
PMID: 5917034
Angiostatic activity and metabolism of cortisol in the chorioallantoic membrane (CAM) of the chick embryo.
McNatt LG, Lane D, Clark AF., J. Steroid Biochem. Mol. Biol. 42(7), 1992
PMID: 1380295
Toward a dynamic model of deposition and utilization of yolk steroids.
Moore MC, Johnston GI., Integr. Comp. Biol. 48(3), 2008
PMID: 21669802
Manipulative signals in family conflict? On the function of maternal yolk hormones in birds.
Muller W, Lessells CK, Korsten P, von Engelhardt N., Am. Nat. 169(4), 2007
PMID: 17253431
The formation of sub-blastodermic fluid in hens eggs
New, Journal of Embryology and Experimental Morphology 4(), 1956
Expression of five steroidogenic genes including aromatase gene at early developmental stages of chicken male and female embryos.
Nomura O, Nakabayashi O, Nishimori K, Yasue H, Mizuno S., J. Steroid Biochem. Mol. Biol. 71(3-4), 1999
PMID: 10659698
Transport, binding, and metabolism of sulfate conjugates in the liver.
Pang KS, Schwab AJ, Goresky CA, Chiba M., Chem. Biol. Interact. 92(1-3), 1994
PMID: 8033253
Corticosterone in chicken eggs.
Rettenbacher S, Mostl E, Hackl R, Palme R., Ann. N. Y. Acad. Sci. 1046(), 2005
PMID: 16055852
Assimilation of avian yolk and albumen under normal and extreme incubating temperatures
Romanoff, The Anatomical Record 86(), 1943
Yolk is a source of maternal testosterone for developing birds.
Schwabl H., Proc. Natl. Acad. Sci. U.S.A. 90(24), 1993
PMID: 8265571
Gonadal sex differentiation in chicken embryos: expression of estrogen receptor and aromatase genes.
Smith CA, Andrews JE, Sinclair AH., J. Steroid Biochem. Mol. Biol. 60(5-6), 1997
PMID: 9219920
Regulation of substances in allantoic and amniotic fluid of the chicken embryo
ten, Comparative Biochemistry and Physiology A: Physiology 116(), 1997
Measuring steroid hormones in avian eggs.
von Engelhardt N, Groothuis TG., Ann. N. Y. Acad. Sci. 1046(), 2005
PMID: 16055851
Ontogenesis of the pituitary-gonadal axis in the chick embryo.
Woods JE, Weeks RL., Gen. Comp. Endocrinol. 13(2), 1969
PMID: 5403618

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