Developmental effects on dopamine projections and hippocampal cell proliferation in the rodent model of postweaning social and physical deprivation can be triggered by brief changes of environmental context

Lehmann K, Grund T, Bagorda A, Bagorda F, Grafen K, Winter Y, Teuchert-Noodt G (2009)
BEHAVIOURAL BRAIN RESEARCH 205(1): 26-31.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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DOI
Autor*in
Lehmann, Konrad; Grund, Thorsten; Bagorda, Anja; Bagorda, FrancescoUniBi; Grafen, Keren; Winter, York; Teuchert-Noodt, GertraudUniBi
Einrichtung
Fakultät für Biologie
Center of Excellence - Cognitive Interaction Technology CITEC
Abstract / Bemerkung
Periadolescence is a critical period during which environmental stimuli modulate developmental neural plasticity. This includes the density of mesolimbic dopamine (DA) projections and the mitotic dynamic in the hippocampal dentate gyrus, both involved in central structures for emotional and cognitive functioning. Behavioural tests suggest that even short periods of stimulation can have lasting developmental effects on cognitive and emotional measures. We therefore exposed animals kept in isolation to brief daily context changes during periadolescence (postnatal days 30-60). We assessed the effects on neural development after animals had reached adulthood at postnatal day 90 by measuring the density of dopamine fibres in the medial prefrontal cortex (PFC), nucleus accumbens (core and shelf), olfactory tubercle, and amygdala (basolateral and central), and by labelling mitoses in the dentate gyrus by BrdU. In experimental animals as compared to deprived controls, dopamine fibre densities were increased in the PFC and basolateral amygdala, decreased in the central amygdala, but not altered in the ventral striatum. Hippocampal cell proliferation was decreased. These results show that even a low level of experimental sensory stimulation during periadolescence triggers neural developmental processes, with lasting effects into adulthood. (C) 2009 Elsevier B.V. All rights reserved
Stichworte
Rearing environment; Dopamine; Dentate gyrus; Amygdala; Nucleus accumbens; Cell proliferation; Periadolescence; Prefrontal cortex
Erscheinungsjahr
2009
Zeitschriftentitel
BEHAVIOURAL BRAIN RESEARCH
Band
205
Ausgabe
1
Seite(n)
26-31
ISSN
0166-4328
Page URI
https://pub.uni-bielefeld.de/record/1590215

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Lehmann K, Grund T, Bagorda A, et al. Developmental effects on dopamine projections and hippocampal cell proliferation in the rodent model of postweaning social and physical deprivation can be triggered by brief changes of environmental context. BEHAVIOURAL BRAIN RESEARCH. 2009;205(1):26-31.
Lehmann, K., Grund, T., Bagorda, A., Bagorda, F., Grafen, K., Winter, Y., & Teuchert-Noodt, G. (2009). Developmental effects on dopamine projections and hippocampal cell proliferation in the rodent model of postweaning social and physical deprivation can be triggered by brief changes of environmental context. BEHAVIOURAL BRAIN RESEARCH, 205(1), 26-31. https://doi.org/10.1016/j.bbr.2009.07.016
Lehmann, Konrad, Grund, Thorsten, Bagorda, Anja, Bagorda, Francesco, Grafen, Keren, Winter, York, and Teuchert-Noodt, Gertraud. 2009. “Developmental effects on dopamine projections and hippocampal cell proliferation in the rodent model of postweaning social and physical deprivation can be triggered by brief changes of environmental context”. BEHAVIOURAL BRAIN RESEARCH 205 (1): 26-31.
Lehmann, K., Grund, T., Bagorda, A., Bagorda, F., Grafen, K., Winter, Y., and Teuchert-Noodt, G. (2009). Developmental effects on dopamine projections and hippocampal cell proliferation in the rodent model of postweaning social and physical deprivation can be triggered by brief changes of environmental context. BEHAVIOURAL BRAIN RESEARCH 205, 26-31.
Lehmann, K., et al., 2009. Developmental effects on dopamine projections and hippocampal cell proliferation in the rodent model of postweaning social and physical deprivation can be triggered by brief changes of environmental context. BEHAVIOURAL BRAIN RESEARCH, 205(1), p 26-31.
K. Lehmann, et al., “Developmental effects on dopamine projections and hippocampal cell proliferation in the rodent model of postweaning social and physical deprivation can be triggered by brief changes of environmental context”, BEHAVIOURAL BRAIN RESEARCH, vol. 205, 2009, pp. 26-31.
Lehmann, K., Grund, T., Bagorda, A., Bagorda, F., Grafen, K., Winter, Y., Teuchert-Noodt, G.: Developmental effects on dopamine projections and hippocampal cell proliferation in the rodent model of postweaning social and physical deprivation can be triggered by brief changes of environmental context. BEHAVIOURAL BRAIN RESEARCH. 205, 26-31 (2009).
Lehmann, Konrad, Grund, Thorsten, Bagorda, Anja, Bagorda, Francesco, Grafen, Keren, Winter, York, and Teuchert-Noodt, Gertraud. “Developmental effects on dopamine projections and hippocampal cell proliferation in the rodent model of postweaning social and physical deprivation can be triggered by brief changes of environmental context”. BEHAVIOURAL BRAIN RESEARCH 205.1 (2009): 26-31.

54 References

Daten bereitgestellt von Europe PubMed Central.

Dopamine receptor pruning in prefrontal cortex during the periadolescent period in rats.
Andersen SL, Thompson AT, Rutstein M, Hostetter JC, Teicher MH., Synapse 37(2), 2000
PMID: 10881038
Isolation rearing or methamphetamine traumatisation induce a "dysconnection" of prefrontal efferents in gerbils: implications for schizophrenia.
Bagorda F, Teuchert-Noodt G, Lehmann K., J Neural Transm (Vienna) 113(3), 2005
PMID: 15959840
Response to stress of mesocortico-frontal dopaminergic neurones in rats after long-term isolation.
Blanc G, Herve D, Simon H, Lisoprawski A, Glowinski J, Tassin JP., Nature 284(5753), 1980
PMID: 7189015
Subsensitivity to dopaminergic drugs in periadolescent rats: a behavioral and neurochemical analysis.
Bolanos CA, Glatt SJ, Jackson D., Brain Res. Dev. Brain Res. 111(1), 1998
PMID: 9804875
Maternal separation followed by early social deprivation affects the development of monoaminergic fiber systems in the medial prefrontal cortex of Octodon degus.
Braun K, Lange E, Metzger M, Poeggel G., Neuroscience 95(1), 2000
PMID: 10619487
Developmentally induced imbalance of dopaminergic fibre densities in limbic brain regions of gerbils ( Meriones unguiculatus).
Busche A, Polascheck D, Lesting J, Neddens J, Teuchert-Noodt G., J Neural Transm (Vienna) 111(4), 2004
PMID: 15057515
The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors.
Busche A, Bagorda A, Lehmann K, Neddens J, Teuchert-Noodt G., J Neural Transm (Vienna) 113(2), 2005
PMID: 15959847
Cocaine differentially alters behavior and neurochemistry in periadolescent versus adult rats.
Collins SL, Izenwasser S., Brain Res. Dev. Brain Res. 138(1), 2002
PMID: 12234655
Maturation of the dopamine innervation during postnatal development of the prefrontal cortex in gerbils (Meriones unguiculatus). A quantitative immunocytochemical study.
Dawirs RR, Teuchert-Noodt G, Czaniera R., J Hirnforsch 34(3), 1993
PMID: 8270782
The postnatal maturation of dopamine innervation in the prefrontal cortex of gerbils (Meriones unguiculatus) is sensitive to an early single dose of methamphetamine. A quantitative immunocytochemical study
Dawirs, J Brain Res 35(), 1994
Ontogeny of PFC-related behaviours is sensitive to a single non-invasive dose of methamphetamine in neonatal gerbils (Meriones unguiculatus).
Dawirs RR, Teuchert-Noodt G, Czaniera R., J Neural Transm (Vienna) 103(11), 1996
PMID: 9013410
Periadolescent mice show enhanced DeltaFosB upregulation in response to cocaine and amphetamine.
Ehrlich ME, Sommer J, Canas E, Unterwald EM., J. Neurosci. 22(21), 2002
PMID: 12417638
A critical period for social isolation in the rat.
Einon DF, Morgan MJ., Dev Psychobiol 10(2), 1977
PMID: 838157
Forty minutes of experience increase the weight and RNA content of cerebral cortex in periadolescent rats.
Ferchmin PA, Eterovic VA., Dev Psychobiol 19(6), 1986
PMID: 2433174
Environmental enrichment reverses the effects of maternal separation on stress reactivity.
Francis DD, Diorio J, Plotsky PM, Meaney MJ., J. Neurosci. 22(18), 2002
PMID: 12223535
Social deprivation of neonatal, adolescent, and adult rats has distinct neurochemical and behavioral consequences.
Hall FS., Crit Rev Neurobiol 12(1-2), 1998
PMID: 9444483
Isolation rearing in rats: pre- and postsynaptic changes in striatal dopaminergic systems.
Hall FS, Wilkinson LS, Humby T, Inglis W, Kendall DA, Marsden CA, Robbins TW., Pharmacol. Biochem. Behav. 59(4), 1998
PMID: 9586842
Behavioral, neurochemical and endocrinological characterization of the early social isolation syndrome.
Heidbreder CA, Weiss IC, Domeney AM, Pryce C, Homberg J, Hedou G, Feldon J, Moran MC, Nelson P., Neuroscience 100(4), 2000
PMID: 11036209
Critical period regulation.
Hensch TK., Annu. Rev. Neurosci. 27(), 2004
PMID: 15217343
A single neonatal dose of methamphetamine suppresses dentate granule cell proliferation in adult gerbils which is restored to control values by acute doses of haloperidol.
Hildebrandt K, Teuchert-Noodt G, Dawirs RR., J Neural Transm (Vienna) 106(5-6), 1999
PMID: 10443557
"Isolation stress" revisited: isolation-rearing effects depend on animal care methods.
Holson RR, Scallet AC, Ali SF, Turner BB., Physiol. Behav. 49(6), 1991
PMID: 1896492
Dopaminergic and serotonergic function following isolation rearing in rats: study of behavioural responses and postmortem and in vivo neurochemistry.
Jones GH, Hernandez TD, Kendall DA, Marsden CA, Robbins TW., Pharmacol. Biochem. Behav. 43(1), 1992
PMID: 1384071
Effects of enriched and of restricted rearing on both neurogenesis and synaptogenesis in the hippocampal dentate gyrus of adult gerbils (Meriones unguiculatus)
Keller, Neurol Psychiatry Brain Res 8(), 2000
Natural variation and genetic covariance in adult hippocampal neurogenesis.
Kempermann G, Chesler EJ, Lu L, Williams RW, Gage FH., Proc. Natl. Acad. Sci. U.S.A. 103(3), 2006
PMID: 16407118
More hippocampal neurons in adult mice living in an enriched environment.
Kempermann G, Kuhn HG, Gage FH., Nature 386(6624), 1997
PMID: 9087407
Post-weaning handling attenuates isolation-rearing induced disruptions of prepulse inhibition in rats.
Krebs-Thomson K, Giracello D, Solis A, Geyer MA., Behav. Brain Res. 120(2), 2001
PMID: 11182170
Influence of postweaning social isolation in the rat on brain development, conditioned behaviour and neurotransmission.
Lapiz MD, Fulford A, Muchimapura S, Mason R, Parker T, Marsden CA., Ross Fiziol Zh Im I M Sechenova 87(6), 2001
PMID: 11534200
Serotonin fibre densities in subcortical areas: differential effects of isolated rearing and methamphetamine.
Lehmann K, Lesting J, Polascheck D, Teuchert-Noodt G., Brain Res. Dev. Brain Res. 147(1-2), 2003
PMID: 14741759
The acetylcholine fiber density of the neocortex is altered by isolated rearing and early methamphetamine intoxication in rodents.
Lehmann K, Hundsdorfer B, Hartmann T, Teuchert-Noodt G., Exp. Neurol. 189(1), 2004
PMID: 15296843
Offer and demand: proliferation and survival of neurons in the dentate gyrus.
Lehmann K, Butz M, Teuchert-Noodt G., Eur. J. Neurosci. 21(12), 2005
PMID: 16026459
Hemisphere-specific effects on serotonin but not dopamine innervation in the nucleus accumbens of gerbils caused by isolated rearing and a single early methamphetamine challenge.
Lesting J, Neddens J, Busche A, Teuchert-Noodt G., Brain Res. 1035(2), 2005
PMID: 15722056
Ontogeny of the dopamine innervation in the nucleus accumbens of gerbils.
Lesting J, Neddens J, Teuchert-Noodt G., Brain Res. 1066(1-2), 2005
PMID: 16343448
Maternal care, hippocampal synaptogenesis and cognitive development in rats.
Liu D, Diorio J, Day JC, Francis DD, Meaney MJ., Nat. Neurosci. 3(8), 2000
PMID: 10903573
Modification of hippocampal neurogenesis and neuroplasticity by social environments.
Lu L, Bao G, Chen H, Xia P, Fan X, Zhang J, Pei G, Ma L., Exp. Neurol. 183(2), 2003
PMID: 14552901
Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations.
Meaney MJ., Annu. Rev. Neurosci. 24(), 2001
PMID: 11520931
Differential environment alters ontogeny of dopamine innervation of the orbital prefrontal cortex in gerbils.
Neddens J, Brandenburg K, Teuchert-Noodt G, Dawirs RR., J. Neurosci. Res. 63(2), 2001
PMID: 11169631
Epigenetic factors differentially influence postnatal maturation of serotonin (5-HT) innervation in cerebral cortex of gerbils: interaction of rearing conditions and early methamphetamine challenge.
Neddens J, Bagorda F, Busche A, Horstmann S, Moll GH, Dawirs RR, Teuchert-Noodt G., Brain Res. Dev. Brain Res. 146(1-2), 2003
PMID: 14643018
Parental depression: animal models of an adverse life event.
Newport DJ, Stowe ZN, Nemeroff CB., Am J Psychiatry 159(8), 2002
PMID: 12153816

Paxinos, 1986
A rodent model of spontaneous stereotypy: initial characterization of developmental, environmental, and neurobiological factors.
Powell SB, Newman HA, Pendergast JF, Lewis MH., Physiol. Behav. 66(2), 1999
PMID: 10336165
Handling and isolation in three strains of rats affect open field, exploration, hoarding and predation.
Reboucas RC, Schmidek WR., Physiol. Behav. 62(5), 1997
PMID: 9333213
Effects of differential environments on brain weights and enzyme activities in gerbils, rats, and mice.
Rosenzweig MR, Bennett EL., Dev Psychobiol 2(2), 1969
PMID: 5407659
Social grouping cannot account for cerebral effects of enriched environments.
Rosenzweig MR, Bennett EL, Hebert M, Morimoto H., Brain Res. 153(3), 1978
PMID: 698794
Development of place navigation in rats from weaning to puberty.
Schenk F., Behav. Neural Biol. 43(1), 1985
PMID: 3994625
Animal models of periadolescent substance abuse.
Smith RF., Neurotoxicol Teratol 25(3), 2003
PMID: 12757826
Periadolescence: age-dependent behavior and psychopharmacological responsivity in rats.
Spear LP, Brake SC., Dev Psychobiol 16(2), 1983
PMID: 6339302
Evidence for dopamine receptor pruning between adolescence and adulthood in striatum but not nucleus accumbens.
Teicher MH, Andersen SL, Hostetter JC Jr., Brain Res. Dev. Brain Res. 89(2), 1995
PMID: 8612321
Adult treatment with methamphetamine transiently decreases dentate granule cell proliferation in the gerbil hippocampus.
Teuchert-Noodt G, Dawirs RR, Hildebrandt K., J Neural Transm (Vienna) 107(2), 2000
PMID: 10847555
Ontogeny of the sexually dimorphic area of the gerbil hypothalamus.
Ulibarri CM, Yahr P., Brain Res. Dev. Brain Res. 74(1), 1993
PMID: 8403369
Cortical maldevelopment, anti-psychotic drugs, and schizophrenia: a search for common ground.
Weinberger DR, Lipska BK., Schizophr. Res. 16(2), 1995
PMID: 7577773
Hippocampal function during adolescence: a unique target of ethanol effects.
White AM, Swartzwelder HS., Ann. N. Y. Acad. Sci. 1021(), 2004
PMID: 15251891
Effects of serotonergic agents on isolation-induced aggression.
White SM, Kucharik RF, Moyer JA., Pharmacol. Biochem. Behav. 39(3), 1991
PMID: 1686105
Social environment alters both ontogeny of dopamine innervation of the medial prefrontal cortex and maturation of working memory in gerbils (Meriones unguiculatus).
Winterfeld KT, Teuchert-Noodt G, Dawirs RR., J. Neurosci. Res. 52(2), 1998
PMID: 9579410
Evidence for physiological growth of hippocampal mossy fiber collaterals in the guinea pig during puberty and adulthood.
Wolfer DP, Lipp HP., Hippocampus 5(4), 1995
PMID: 8589796
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