The GlxR regulon of the amino acid producer Corynebacterium glutamicum: Detection of the corynebacterial core regulon and integration into the transcriptional regulatory network model
Kohl T, Tauch A (2009)
JOURNAL OF BIOTECHNOLOGY 143(4): 239-246.
Zeitschriftenaufsatz
| Veröffentlicht | Englisch
Download
Es wurden keine Dateien hochgeladen. Nur Publikationsnachweis!
Autor*in
Einrichtung
Abstract / Bemerkung
Corynebacterium glutamicum is an industrially important producer of amino acids and an emerging model system for the Corynebacterineae. The glxR gene of C. glutamicum ATCC 13032 encodes a DNA binding transcription factor of the Crp-Fnr protein family. Available data indicated a prominent role of GlxR in the transcriptional regulatory network of C. glutamicum. We have used recently published whole-genome annotations of several corynebacteria to derive further evidence for GlxR-mediated transcriptional regulation from a comparative genomics approach. A bioinformatic strategy detected 22 genes belonging to a proposed GlxR core regulon in corynebacteria. Binding of purified GlxR protein to 40-mer oligonucleotides representing predicted GlxR binding sites in the upstream region of core genes from C. glutamicum ATCC 13032 was verified in vitro by electrophoretic mobility shift assays. Based on current data, a reliable genome-scale prediction of GlxR binding sites was performed, indicating that about 14% of the annotated C. glutamicum genes might be under direct transcriptional control by GlxR. Integration of GlxR-mediated regulatory interactions with the data stored in CoryneRegNet enabled the reconstruction of a refined transcriptional regulatory network model for C. glutamicum. This network model exhibited a hierarchical and modular structure and is characterized by the presence of master regulators in each functional module, with GlxR serving as the dominating regulatory hub. (C) 2009 Elsevier B.V. All rights reserved.
Stichworte
Corynebacterium glutamicum;
Transcriptional;
regulatory network;
Transcription factor binding site;
Global;
Comparative genomics;
GlxR;
regulator
Erscheinungsjahr
2009
Zeitschriftentitel
JOURNAL OF BIOTECHNOLOGY
Band
143
Ausgabe
4
Seite(n)
239-246
ISSN
0168-1656
Page URI
https://pub.uni-bielefeld.de/record/1589932
Zitieren
Kohl T, Tauch A. The GlxR regulon of the amino acid producer Corynebacterium glutamicum: Detection of the corynebacterial core regulon and integration into the transcriptional regulatory network model. JOURNAL OF BIOTECHNOLOGY. 2009;143(4):239-246.
Kohl, T., & Tauch, A. (2009). The GlxR regulon of the amino acid producer Corynebacterium glutamicum: Detection of the corynebacterial core regulon and integration into the transcriptional regulatory network model. JOURNAL OF BIOTECHNOLOGY, 143(4), 239-246. https://doi.org/10.1016/j.jbiotec.2009.08.005
Kohl, Thomas, and Tauch, Andreas. 2009. “The GlxR regulon of the amino acid producer Corynebacterium glutamicum: Detection of the corynebacterial core regulon and integration into the transcriptional regulatory network model”. JOURNAL OF BIOTECHNOLOGY 143 (4): 239-246.
Kohl, T., and Tauch, A. (2009). The GlxR regulon of the amino acid producer Corynebacterium glutamicum: Detection of the corynebacterial core regulon and integration into the transcriptional regulatory network model. JOURNAL OF BIOTECHNOLOGY 143, 239-246.
Kohl, T., & Tauch, A., 2009. The GlxR regulon of the amino acid producer Corynebacterium glutamicum: Detection of the corynebacterial core regulon and integration into the transcriptional regulatory network model. JOURNAL OF BIOTECHNOLOGY, 143(4), p 239-246.
T. Kohl and A. Tauch, “The GlxR regulon of the amino acid producer Corynebacterium glutamicum: Detection of the corynebacterial core regulon and integration into the transcriptional regulatory network model”, JOURNAL OF BIOTECHNOLOGY, vol. 143, 2009, pp. 239-246.
Kohl, T., Tauch, A.: The GlxR regulon of the amino acid producer Corynebacterium glutamicum: Detection of the corynebacterial core regulon and integration into the transcriptional regulatory network model. JOURNAL OF BIOTECHNOLOGY. 143, 239-246 (2009).
Kohl, Thomas, and Tauch, Andreas. “The GlxR regulon of the amino acid producer Corynebacterium glutamicum: Detection of the corynebacterial core regulon and integration into the transcriptional regulatory network model”. JOURNAL OF BIOTECHNOLOGY 143.4 (2009): 239-246.
Daten bereitgestellt von European Bioinformatics Institute (EBI)
29 Zitationen in Europe PMC
Daten bereitgestellt von Europe PubMed Central.
The RamA regulon: complex regulatory interactions in relation to central metabolism in Corynebacterium glutamicum.
Shah A, Blombach B, Gauttam R, Eikmanns BJ., Appl Microbiol Biotechnol 102(14), 2018
PMID: 29804137
Shah A, Blombach B, Gauttam R, Eikmanns BJ., Appl Microbiol Biotechnol 102(14), 2018
PMID: 29804137
Identification of the cAMP phosphodiesterase CpdA as novel key player in cAMP-dependent regulation in Corynebacterium glutamicum.
Schulte J, Baumgart M, Bott M., Mol Microbiol 103(3), 2017
PMID: 27862445
Schulte J, Baumgart M, Bott M., Mol Microbiol 103(3), 2017
PMID: 27862445
The Transcriptional Regulators of the CRP Family Regulate Different Essential Bacterial Functions and Can Be Inherited Vertically and Horizontally.
Soberón-Chávez G, Alcaraz LD, Morales E, Ponce-Soto GY, Servín-González L., Front Microbiol 8(), 2017
PMID: 28620358
Soberón-Chávez G, Alcaraz LD, Morales E, Ponce-Soto GY, Servín-González L., Front Microbiol 8(), 2017
PMID: 28620358
Up regulation of glyoxylate reductase/hydroxypyruvate reductase (GRHPR) is associated with intestinal epithelial cells apoptosis in TNBS-induced experimental colitis.
Zong C, Nie X, Zhang D, Ji Q, Qin Y, Wang L, Jiang D, Gong C, Liu Y, Zhou G., Pathol Res Pract 212(5), 2016
PMID: 26997491
Zong C, Nie X, Zhang D, Ji Q, Qin Y, Wang L, Jiang D, Gong C, Liu Y, Zhou G., Pathol Res Pract 212(5), 2016
PMID: 26997491
Regulons of global transcription factors in Corynebacterium glutamicum.
Toyoda K, Inui M., Appl Microbiol Biotechnol 100(1), 2016
PMID: 26496920
Toyoda K, Inui M., Appl Microbiol Biotechnol 100(1), 2016
PMID: 26496920
Biosensor-driven adaptive laboratory evolution of l-valine production in Corynebacterium glutamicum.
Mahr R, Gätgens C, Gätgens J, Polen T, Kalinowski J, Frunzke J., Metab Eng 32(), 2015
PMID: 26453945
Mahr R, Gätgens C, Gätgens J, Polen T, Kalinowski J, Frunzke J., Metab Eng 32(), 2015
PMID: 26453945
Recent progress in development of synthetic biology platforms and metabolic engineering of Corynebacterium glutamicum.
Woo HM, Park JB., J Biotechnol 180(), 2014
PMID: 24632177
Woo HM, Park JB., J Biotechnol 180(), 2014
PMID: 24632177
Role of Corynebacterium glutamicum sprA encoding a serine protease in glxR-mediated global gene regulation.
Hong EJ, Park JS, Kim Y, Lee HS., PLoS One 9(4), 2014
PMID: 24691519
Hong EJ, Park JS, Kim Y, Lee HS., PLoS One 9(4), 2014
PMID: 24691519
Involvement of the global regulator GlxR in 3-hydroxybenzoate and gentisate utilization by Corynebacterium glutamicum.
Chao H, Zhou NY., Appl Environ Microbiol 80(14), 2014
PMID: 24795375
Chao H, Zhou NY., Appl Environ Microbiol 80(14), 2014
PMID: 24795375
High-resolution detection of DNA binding sites of the global transcriptional regulator GlxR in Corynebacterium glutamicum.
Jungwirth B, Sala C, Kohl TA, Uplekar S, Baumbach J, Cole ST, Pühler A, Tauch A., Microbiology 159(pt 1), 2013
PMID: 23103979
Jungwirth B, Sala C, Kohl TA, Uplekar S, Baumbach J, Cole ST, Pühler A, Tauch A., Microbiology 159(pt 1), 2013
PMID: 23103979
Corynebacterium glutamicum promoters: a practical approach.
Pátek M, Holátko J, Busche T, Kalinowski J, Nešvera J., Microb Biotechnol 6(2), 2013
PMID: 23305350
Pátek M, Holátko J, Busche T, Kalinowski J, Nešvera J., Microb Biotechnol 6(2), 2013
PMID: 23305350
Involvement of regulatory interactions among global regulators GlxR, SugR, and RamA in expression of ramA in Corynebacterium glutamicum.
Toyoda K, Teramoto H, Gunji W, Inui M, Yukawa H., J Bacteriol 195(8), 2013
PMID: 23396909
Toyoda K, Teramoto H, Gunji W, Inui M, Yukawa H., J Bacteriol 195(8), 2013
PMID: 23396909
Crystal and solution studies reveal that the transcriptional regulator AcnR of Corynebacterium glutamicum is regulated by citrate-Mg2+ binding to a non-canonical pocket.
García-Nafría J, Baumgart M, Turkenburg JP, Wilkinson AJ, Bott M, Wilson KS., J Biol Chem 288(22), 2013
PMID: 23589369
García-Nafría J, Baumgart M, Turkenburg JP, Wilkinson AJ, Bott M, Wilson KS., J Biol Chem 288(22), 2013
PMID: 23589369
Proteome response of Corynebacterium glutamicum to high concentration of industrially relevant C₄ and C₅ dicarboxylic acids.
Vasco-Cárdenas MF, Baños S, Ramos A, Martín JF, Barreiro C., J Proteomics 85(), 2013
PMID: 23624027
Vasco-Cárdenas MF, Baños S, Ramos A, Martín JF, Barreiro C., J Proteomics 85(), 2013
PMID: 23624027
Complex regulation of the phosphoenolpyruvate carboxykinase gene pck and characterization of its GntR-type regulator IolR as a repressor of myo-inositol utilization genes in Corynebacterium glutamicum.
Klaffl S, Brocker M, Kalinowski J, Eikmanns BJ, Bott M., J Bacteriol 195(18), 2013
PMID: 23873914
Klaffl S, Brocker M, Kalinowski J, Eikmanns BJ, Bott M., J Bacteriol 195(18), 2013
PMID: 23873914
Biotin protein ligase from Corynebacterium glutamicum: role for growth and L: -lysine production.
Peters-Wendisch P, Stansen KC, Götker S, Wendisch VF., Appl Microbiol Biotechnol 93(6), 2012
PMID: 22159614
Peters-Wendisch P, Stansen KC, Götker S, Wendisch VF., Appl Microbiol Biotechnol 93(6), 2012
PMID: 22159614
Binding of the IclR-type regulator HutR in the histidine utilization (hut) gene cluster of the human pathogen Corynebacterium resistens DSM 45100.
Schröder J, Maus I, Ostermann AL, Kögler AC, Tauch A., FEMS Microbiol Lett 331(2), 2012
PMID: 22462578
Schröder J, Maus I, Ostermann AL, Kögler AC, Tauch A., FEMS Microbiol Lett 331(2), 2012
PMID: 22462578
Degradation and assimilation of aromatic compounds by Corynebacterium glutamicum: another potential for applications for this bacterium?
Shen XH, Zhou NY, Liu SJ., Appl Microbiol Biotechnol 95(1), 2012
PMID: 22588501
Shen XH, Zhou NY, Liu SJ., Appl Microbiol Biotechnol 95(1), 2012
PMID: 22588501
Phenylacetic acid catabolism and its transcriptional regulation in Corynebacterium glutamicum.
Chen X, Kohl TA, Rückert C, Rodionov DA, Li LH, Ding JY, Kalinowski J, Liu SJ., Appl Environ Microbiol 78(16), 2012
PMID: 22685150
Chen X, Kohl TA, Rückert C, Rodionov DA, Li LH, Ding JY, Kalinowski J, Liu SJ., Appl Environ Microbiol 78(16), 2012
PMID: 22685150
Carotenoid biosynthesis and overproduction in Corynebacterium glutamicum.
Heider SA, Peters-Wendisch P, Wendisch VF., BMC Microbiol 12(), 2012
PMID: 22963379
Heider SA, Peters-Wendisch P, Wendisch VF., BMC Microbiol 12(), 2012
PMID: 22963379
Positive transcriptional control of the pyridoxal phosphate biosynthesis genes pdxST by the MocR-type regulator PdxR of Corynebacterium glutamicum ATCC 13032.
Jochmann N, Götker S, Tauch A., Microbiology 157(pt 1), 2011
PMID: 20847010
Jochmann N, Götker S, Tauch A., Microbiology 157(pt 1), 2011
PMID: 20847010
Regulation of the nitrate reductase operon narKGHJI by the cAMP-dependent regulator GlxR in Corynebacterium glutamicum.
Nishimura T, Teramoto H, Toyoda K, Inui M, Yukawa H., Microbiology 157(pt 1), 2011
PMID: 20864477
Nishimura T, Teramoto H, Toyoda K, Inui M, Yukawa H., Microbiology 157(pt 1), 2011
PMID: 20864477
Control of adhA and sucR expression by the SucR regulator in Corynebacterium glutamicum.
Auchter M, Laslo T, Fleischer C, Schiller L, Arndt A, Gaigalat L, Kalinowski J, Eikmanns BJ., J Biotechnol 152(3), 2011
PMID: 21320555
Auchter M, Laslo T, Fleischer C, Schiller L, Arndt A, Gaigalat L, Kalinowski J, Eikmanns BJ., J Biotechnol 152(3), 2011
PMID: 21320555
Genome-wide identification of in vivo binding sites of GlxR, a cyclic AMP receptor protein-type regulator in Corynebacterium glutamicum.
Toyoda K, Teramoto H, Inui M, Yukawa H., J Bacteriol 193(16), 2011
PMID: 21665967
Toyoda K, Teramoto H, Inui M, Yukawa H., J Bacteriol 193(16), 2011
PMID: 21665967
Deletion of the aconitase gene in Corynebacterium glutamicum causes strong selection pressure for secondary mutations inactivating citrate synthase.
Baumgart M, Mustafi N, Krug A, Bott M., J Bacteriol 193(24), 2011
PMID: 21984793
Baumgart M, Mustafi N, Krug A, Bott M., J Bacteriol 193(24), 2011
PMID: 21984793
Complete genome sequence of Corynebacterium variabile DSM 44702 isolated from the surface of smear-ripened cheeses and insights into cheese ripening and flavor generation.
Schröder J, Maus I, Trost E, Tauch A., BMC Genomics 12(), 2011
PMID: 22053731
Schröder J, Maus I, Trost E, Tauch A., BMC Genomics 12(), 2011
PMID: 22053731
Transcriptional regulation of gene expression in Corynebacterium glutamicum: the role of global, master and local regulators in the modular and hierarchical gene regulatory network.
Schröder J, Tauch A., FEMS Microbiol Rev 34(5), 2010
PMID: 20491930
Schröder J, Tauch A., FEMS Microbiol Rev 34(5), 2010
PMID: 20491930
Regulation of genes involved in sugar uptake, glycolysis and lactate production in Corynebacterium glutamicum.
Teramoto H, Inui M, Yukawa H., Future Microbiol 5(10), 2010
PMID: 21073308
Teramoto H, Inui M, Yukawa H., Future Microbiol 5(10), 2010
PMID: 21073308
The complete genome sequence of Corynebacterium pseudotuberculosis FRC41 isolated from a 12-year-old girl with necrotizing lymphadenitis reveals insights into gene-regulatory networks contributing to virulence.
Trost E, Ott L, Schneider J, Schröder J, Jaenicke S, Goesmann A, Husemann P, Stoye J, Dorella FA, Rocha FS, Soares Sde C, D'Afonseca V, Miyoshi A, Ruiz J, Silva A, Azevedo V, Burkovski A, Guiso N, Join-Lambert OF, Kayal S, Tauch A., BMC Genomics 11(), 2010
PMID: 21192786
Trost E, Ott L, Schneider J, Schröder J, Jaenicke S, Goesmann A, Husemann P, Stoye J, Dorella FA, Rocha FS, Soares Sde C, D'Afonseca V, Miyoshi A, Ruiz J, Silva A, Azevedo V, Burkovski A, Guiso N, Join-Lambert OF, Kayal S, Tauch A., BMC Genomics 11(), 2010
PMID: 21192786
45 References
Daten bereitgestellt von Europe PubMed Central.
Global gene expression mediated by Thermus thermophilus SdrP, a CRP/FNR family transcriptional regulator.
Agari Y, Kashihara A, Yokoyama S, Kuramitsu S, Shinkai A., Mol. Microbiol. 70(1), 2008
PMID: 18699868
Agari Y, Kashihara A, Yokoyama S, Kuramitsu S, Shinkai A., Mol. Microbiol. 70(1), 2008
PMID: 18699868
Characterization of Mycobacterium tuberculosis Rv3676 (CRPMt), a cyclic AMP receptor protein-like DNA binding protein.
Bai G, McCue LA, McDonough KA., J. Bacteriol. 187(22), 2005
PMID: 16267303
Bai G, McCue LA, McDonough KA., J. Bacteriol. 187(22), 2005
PMID: 16267303
The Mycobacterium bovis BCG cyclic AMP receptor-like protein is a functional DNA binding protein in vitro and in vivo, but its activity differs from that of its M. tuberculosis ortholog, Rv3676.
Bai G, Gazdik MA, Schaak DD, McDonough KA., Infect. Immun. 75(11), 2007
PMID: 17785469
Bai G, Gazdik MA, Schaak DD, McDonough KA., Infect. Immun. 75(11), 2007
PMID: 17785469
Transcription regulation by tandem-bound FNR at Escherichia coli promoters.
Barnard AM, Green J, Busby SJ., J. Bacteriol. 185(20), 2003
PMID: 14526010
Barnard AM, Green J, Busby SJ., J. Bacteriol. 185(20), 2003
PMID: 14526010
Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms.
Baumbach J, Rahmann S, Tauch A., BMC Syst Biol 3(), 2009
PMID: 19146695
Baumbach J, Rahmann S, Tauch A., BMC Syst Biol 3(), 2009
PMID: 19146695
Fast index based algorithms and software for matching position specific scoring matrices.
Beckstette M, Homann R, Giegerich R, Kurtz S., BMC Bioinformatics 7(), 2006
PMID: 16930469
Beckstette M, Homann R, Giegerich R, Kurtz S., BMC Bioinformatics 7(), 2006
PMID: 16930469
Correlation between growth rates, EIIACrr phosphorylation, and intracellular cyclic AMP levels in Escherichia coli K-12.
Bettenbrock K, Sauter T, Jahreis K, Kremling A, Lengeler JW, Gilles ED., J. Bacteriol. 189(19), 2007
PMID: 17675376
Bettenbrock K, Sauter T, Jahreis K, Kremling A, Lengeler JW, Gilles ED., J. Bacteriol. 189(19), 2007
PMID: 17675376
The transcriptional regulatory network of the amino acid producer Corynebacterium glutamicum.
Brinkrolf K, Brune I, Tauch A., J. Biotechnol. 129(2), 2006
PMID: 17227685
Brinkrolf K, Brune I, Tauch A., J. Biotechnol. 129(2), 2006
PMID: 17227685
The individual and common repertoire of DNA-binding transcriptional regulators of Corynebacterium glutamicum, Corynebacterium efficiens, Corynebacterium diphtheriae and Corynebacterium jeikeium deduced from the complete genome sequences.
Brune I, Brinkrolf K, Kalinowski J, Puhler A, Tauch A., BMC Genomics 6(), 2005
PMID: 15938759
Brune I, Brinkrolf K, Kalinowski J, Puhler A, Tauch A., BMC Genomics 6(), 2005
PMID: 15938759
The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129.
Cerdeno-Tarraga AM, Efstratiou A, Dover LG, Holden MT, Pallen M, Bentley SD, Besra GS, Churcher C, James KD, De Zoysa A, Chillingworth T, Cronin A, Dowd L, Feltwell T, Hamlin N, Holroyd S, Jagels K, Moule S, Quail MA, Rabbinowitsch E, Rutherford KM, Thomson NR, Unwin L, Whitehead S, Barrell BG, Parkhill J., Nucleic Acids Res. 31(22), 2003
PMID: 14602910
Cerdeno-Tarraga AM, Efstratiou A, Dover LG, Holden MT, Pallen M, Bentley SD, Besra GS, Churcher C, James KD, De Zoysa A, Chillingworth T, Cronin A, Dowd L, Feltwell T, Hamlin N, Holroyd S, Jagels K, Moule S, Quail MA, Rabbinowitsch E, Rutherford KM, Thomson NR, Unwin L, Whitehead S, Barrell BG, Parkhill J., Nucleic Acids Res. 31(22), 2003
PMID: 14602910
The mechanisms of carbon catabolite repression in bacteria.
Deutscher J., Curr. Opin. Microbiol. 11(2), 2008
PMID: 18359269
Deutscher J., Curr. Opin. Microbiol. 11(2), 2008
PMID: 18359269
Functional architecture of Escherichia coli: new insights provided by a natural decomposition approach.
Freyre-Gonzalez JA, Alonso-Pavon JA, Trevino-Quintanilla LG, Collado-Vides J., Genome Biol. 9(10), 2008
PMID: 18954463
Freyre-Gonzalez JA, Alonso-Pavon JA, Trevino-Quintanilla LG, Collado-Vides J., Genome Biol. 9(10), 2008
PMID: 18954463
Expression of Corynebacterium glutamicum glycolytic genes varies with carbon source and growth phase.
Han SO, Inui M, Yukawa H., Microbiology (Reading, Engl.) 153(Pt 7), 2007
PMID: 17600063
Han SO, Inui M, Yukawa H., Microbiology (Reading, Engl.) 153(Pt 7), 2007
PMID: 17600063
Effect of carbon source availability and growth phase on expression of Corynebacterium glutamicum genes involved in the tricarboxylic acid cycle and glyoxylate bypass.
Han SO, Inui M, Yukawa H., Microbiology (Reading, Engl.) 154(Pt 10), 2008
PMID: 18832313
Han SO, Inui M, Yukawa H., Microbiology (Reading, Engl.) 154(Pt 10), 2008
PMID: 18832313
The surface (S)-layer gene cspB of Corynebacterium glutamicum is transcriptionally activated by a LuxR-type regulator and located on a 6 kb genomic island absent from the type strain ATCC 13032.
Hansmeier N, Albersmeier A, Tauch A, Damberg T, Ros R, Anselmetti D, Puhler A, Kalinowski J., Microbiology (Reading, Engl.) 152(Pt 4), 2006
PMID: 16549657
Hansmeier N, Albersmeier A, Tauch A, Damberg T, Ros R, Anselmetti D, Puhler A, Kalinowski J., Microbiology (Reading, Engl.) 152(Pt 4), 2006
PMID: 16549657
Clp upregulates transcription of engA gene encoding a virulence factor in Xanthomonas campestris by direct binding to the upstream tandem Clp sites.
Hsiao YM, Liao HY, Lee MC, Yang TC, Tseng YH., FEBS Lett. 579(17), 2005
PMID: 15955530
Hsiao YM, Liao HY, Lee MC, Yang TC, Tseng YH., FEBS Lett. 579(17), 2005
PMID: 15955530
Measuring genome evolution.
Huynen MA, Bork P., Proc. Natl. Acad. Sci. U.S.A. 95(11), 1998
PMID: 9600883
Huynen MA, Bork P., Proc. Natl. Acad. Sci. U.S.A. 95(11), 1998
PMID: 9600883
Triple transcriptional control of the resuscitation promoting factor 2 (rpf2) gene of Corynebacterium glutamicum by the regulators of acetate metabolism RamA and RamB and the cAMP-dependent regulator GlxR.
Jungwirth B, Emer D, Brune I, Hansmeier N, Puhler A, Eikmanns BJ, Tauch A., FEMS Microbiol. Lett. 281(2), 2008
PMID: 18355281
Jungwirth B, Emer D, Brune I, Hansmeier N, Puhler A, Eikmanns BJ, Tauch A., FEMS Microbiol. Lett. 281(2), 2008
PMID: 18355281
The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.
Kalinowski J, Bathe B, Bartels D, Bischoff N, Bott M, Burkovski A, Dusch N, Eggeling L, Eikmanns BJ, Gaigalat L, Goesmann A, Hartmann M, Huthmacher K, Kramer R, Linke B, McHardy AC, Meyer F, Mockel B, Pfefferle W, Puhler A, Rey DA, Ruckert C, Rupp O, Sahm H, Wendisch VF, Wiegrabe I, Tauch A., J. Biotechnol. 104(1-3), 2003
PMID: 12948626
Kalinowski J, Bathe B, Bartels D, Bischoff N, Bott M, Burkovski A, Dusch N, Eggeling L, Eikmanns BJ, Gaigalat L, Goesmann A, Hartmann M, Huthmacher K, Kramer R, Linke B, McHardy AC, Meyer F, Mockel B, Pfefferle W, Puhler A, Rey DA, Ruckert C, Rupp O, Sahm H, Wendisch VF, Wiegrabe I, Tauch A., J. Biotechnol. 104(1-3), 2003
PMID: 12948626
Characterization of DNA-binding specificity and analysis of binding sites of the Pseudomonas aeruginosa global regulator, Vfr, a homologue of the Escherichia coli cAMP receptor protein.
Kanack KJ, Runyen-Janecky LJ, Ferrell EP, Suh SJ, West SE., Microbiology (Reading, Engl.) 152(Pt 12), 2006
PMID: 17159200
Kanack KJ, Runyen-Janecky LJ, Ferrell EP, Suh SJ, West SE., Microbiology (Reading, Engl.) 152(Pt 12), 2006
PMID: 17159200
Identification and characterization of glxR, a gene involved in regulation of glyoxylate bypass in Corynebacterium glutamicum.
Kim HJ, Kim TH, Kim Y, Lee HS., J. Bacteriol. 186(11), 2004
PMID: 15150232
Kim HJ, Kim TH, Kim Y, Lee HS., J. Bacteriol. 186(11), 2004
PMID: 15150232
In silico genome-scale reconstruction and validation of the Corynebacterium glutamicum metabolic network.
Kjeldsen KR, Nielsen J., Biotechnol. Bioeng. 102(2), 2009
PMID: 18985611
Kjeldsen KR, Nielsen J., Biotechnol. Bioeng. 102(2), 2009
PMID: 18985611
The GlxR regulon of the amino acid producer Corynebacterium glutamicum: in silico and in vitro detection of DNA binding sites of a global transcription regulator.
Kohl TA, Baumbach J, Jungwirth B, Puhler A, Tauch A., J. Biotechnol. 135(4), 2008
PMID: 18573287
Kohl TA, Baumbach J, Jungwirth B, Puhler A, Tauch A., J. Biotechnol. 135(4), 2008
PMID: 18573287
Transcriptional regulation by cAMP and its receptor protein.
Kolb A, Busby S, Buc H, Garges S, Adhya S., Annu. Rev. Biochem. 62(), 1993
PMID: 8394684
Kolb A, Busby S, Buc H, Garges S, Adhya S., Annu. Rev. Biochem. 62(), 1993
PMID: 8394684
Phylogeny of the bacterial superfamily of Crp-Fnr transcription regulators: exploiting the metabolic spectrum by controlling alternative gene programs.
Korner H, Sofia HJ, Zumft WG., FEMS Microbiol. Rev. 27(5), 2003
PMID: 14638413
Korner H, Sofia HJ, Zumft WG., FEMS Microbiol. Rev. 27(5), 2003
PMID: 14638413
Characterization and use of catabolite-repressed promoters from gluconate genes in Corynebacterium glutamicum.
Letek M, Valbuena N, Ramos A, Ordonez E, Gil JA, Mateos LM., J. Bacteriol. 188(2), 2006
PMID: 16385030
Letek M, Valbuena N, Ramos A, Ordonez E, Gil JA, Mateos LM., J. Bacteriol. 188(2), 2006
PMID: 16385030
Hierarchical structure and modules in the Escherichia coli transcriptional regulatory network revealed by a new top-down approach.
Ma HW, Buer J, Zeng AP., BMC Bioinformatics 5(), 2004
PMID: 15603590
Ma HW, Buer J, Zeng AP., BMC Bioinformatics 5(), 2004
PMID: 15603590
Evolutionary dynamics of prokaryotic transcriptional regulatory networks.
Madan Babu M, Teichmann SA, Aravind L., J. Mol. Biol. 358(2), 2006
PMID: 16530225
Madan Babu M, Teichmann SA, Aravind L., J. Mol. Biol. 358(2), 2006
PMID: 16530225
Functional organisation of Escherichia coli transcriptional regulatory network.
Martinez-Antonio A, Janga SC, Thieffry D., J. Mol. Biol. 381(1), 2008
PMID: 18599074
Martinez-Antonio A, Janga SC, Thieffry D., J. Mol. Biol. 381(1), 2008
PMID: 18599074
The phosphotransferase system of Corynebacterium glutamicum: features of sugar transport and carbon regulation.
Moon MW, Park SY, Choi SK, Lee JK., J. Mol. Microbiol. Biotechnol. 12(1-2), 2007
PMID: 17183210
Moon MW, Park SY, Choi SK, Lee JK., J. Mol. Microbiol. Biotechnol. 12(1-2), 2007
PMID: 17183210
Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens.
Nishio Y, Nakamura Y, Kawarabayasi Y, Usuda Y, Kimura E, Sugimoto S, Matsui K, Yamagishi A, Kikuchi H, Ikeo K, Gojobori T., Genome Res. 13(7), 2003
PMID: 12840036
Nishio Y, Nakamura Y, Kawarabayasi Y, Usuda Y, Kimura E, Sugimoto S, Matsui K, Yamagishi A, Kikuchi H, Ikeo K, Gojobori T., Genome Res. 13(7), 2003
PMID: 12840036
In vitro reconstitution of catabolite repression in Escherichia coli.
Park YH, Lee BR, Seok YJ, Peterkofsky A., J. Biol. Chem. 281(10), 2006
PMID: 16407219
Park YH, Lee BR, Seok YJ, Peterkofsky A., J. Biol. Chem. 281(10), 2006
PMID: 16407219
Bacterial nucleotide-based second messengers.
Pesavento C, Hengge R., Curr. Opin. Microbiol. 12(2), 2009
PMID: 19318291
Pesavento C, Hengge R., Curr. Opin. Microbiol. 12(2), 2009
PMID: 19318291
From dormant to germinating spores of Streptomyces coelicolor A3(2): new perspectives from the crp null mutant.
Piette A, Derouaux A, Gerkens P, Noens EE, Mazzucchelli G, Vion S, Koerten HK, Titgemeyer F, De Pauw E, Leprince P, van Wezel GP, Galleni M, Rigali S., J. Proteome Res. 4(5), 2005
PMID: 16212423
Piette A, Derouaux A, Gerkens P, Noens EE, Mazzucchelli G, Vion S, Koerten HK, Titgemeyer F, De Pauw E, Leprince P, van Wezel GP, Galleni M, Rigali S., J. Proteome Res. 4(5), 2005
PMID: 16212423
Characterization of citrate utilization in Corynebacterium glutamicum by transcriptome and proteome analysis.
Polen T, Schluesener D, Poetsch A, Bott M, Wendisch VF., FEMS Microbiol. Lett. 273(1), 2007
PMID: 17559405
Polen T, Schluesener D, Poetsch A, Bott M, Wendisch VF., FEMS Microbiol. Lett. 273(1), 2007
PMID: 17559405
A novel method for accurate operon predictions in all sequenced prokaryotes.
Price MN, Huang KH, Alm EJ, Arkin AP., Nucleic Acids Res. 33(3), 2005
PMID: 15701760
Price MN, Huang KH, Alm EJ, Arkin AP., Nucleic Acids Res. 33(3), 2005
PMID: 15701760
Modular analysis of the transcriptional regulatory network of E. coli.
Resendis-Antonio O, Freyre-Gonzalez JA, Menchaca-Mendez R, Gutierrez-Rios RM, Martinez-Antonio A, Avila-Sanchez C, Collado-Vides J., Trends Genet. 21(1), 2005
PMID: 15680508
Resendis-Antonio O, Freyre-Gonzalez JA, Menchaca-Mendez R, Gutierrez-Rios RM, Martinez-Antonio A, Avila-Sanchez C, Collado-Vides J., Trends Genet. 21(1), 2005
PMID: 15680508
A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of the rpfA gene coding for a resuscitation promoting factor.
Rickman L, Scott C, Hunt DM, Hutchinson T, Menendez MC, Whalan R, Hinds J, Colston MJ, Green J, Buxton RS., Mol. Microbiol. 56(5), 2005
PMID: 15882420
Rickman L, Scott C, Hunt DM, Hutchinson T, Menendez MC, Whalan R, Hinds J, Colston MJ, Green J, Buxton RS., Mol. Microbiol. 56(5), 2005
PMID: 15882420
Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora.
Tauch A, Kaiser O, Hain T, Goesmann A, Weisshaar B, Albersmeier A, Bekel T, Bischoff N, Brune I, Chakraborty T, Kalinowski J, Meyer F, Rupp O, Schneiker S, Viehoever P, Puhler A., J. Bacteriol. 187(13), 2005
PMID: 15968079
Tauch A, Kaiser O, Hain T, Goesmann A, Weisshaar B, Albersmeier A, Bekel T, Bischoff N, Brune I, Chakraborty T, Kalinowski J, Meyer F, Rupp O, Schneiker S, Viehoever P, Puhler A., J. Bacteriol. 187(13), 2005
PMID: 15968079
Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids.
Tauch A, Schneider J, Szczepanowski R, Tilker A, Viehoever P, Gartemann KH, Arnold W, Blom J, Brinkrolf K, Brune I, Gotker S, Weisshaar B, Goesmann A, Droge M, Puhler A., J. Biotechnol. 136(1-2), 2008
PMID: 18430482
Tauch A, Schneider J, Szczepanowski R, Tilker A, Viehoever P, Gartemann KH, Arnold W, Blom J, Brinkrolf K, Brune I, Gotker S, Weisshaar B, Goesmann A, Droge M, Puhler A., J. Biotechnol. 136(1-2), 2008
PMID: 18430482
The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing.
Tauch A, Trost E, Tilker A, Ludewig U, Schneiker S, Goesmann A, Arnold W, Bekel T, Brinkrolf K, Brune I, Gotker S, Kalinowski J, Kamp PB, Lobo FP, Viehoever P, Weisshaar B, Soriano F, Droge M, Puhler A., J. Biotechnol. 136(1-2), 2008
PMID: 18367281
Tauch A, Trost E, Tilker A, Ludewig U, Schneiker S, Goesmann A, Arnold W, Bekel T, Brinkrolf K, Brune I, Gotker S, Kalinowski J, Kamp PB, Lobo FP, Viehoever P, Weisshaar B, Soriano F, Droge M, Puhler A., J. Biotechnol. 136(1-2), 2008
PMID: 18367281
Architectural requirements for optimal activation by tandem CRP molecules at a class I CRP-dependent promoter.
Tebbutt J, Rhodius VA, Webster CL, Busby SJ., FEMS Microbiol. Lett. 210(1), 2002
PMID: 12023077
Tebbutt J, Rhodius VA, Webster CL, Busby SJ., FEMS Microbiol. Lett. 210(1), 2002
PMID: 12023077
Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R.
Yukawa H, Omumasaba CA, Nonaka H, Kos P, Okai N, Suzuki N, Suda M, Tsuge Y, Watanabe J, Ikeda Y, Vertes AA, Inui M., Microbiology (Reading, Engl.) 153(Pt 4), 2007
PMID: 17379713
Yukawa H, Omumasaba CA, Nonaka H, Kos P, Okai N, Suzuki N, Suda M, Tsuge Y, Watanabe J, Ikeda Y, Vertes AA, Inui M., Microbiology (Reading, Engl.) 153(Pt 4), 2007
PMID: 17379713
Mechanism of activation of catabolite-sensitive genes: a positive control system.
Zubay G, Schwartz D, Beckwith J., Proc. Natl. Acad. Sci. U.S.A. 66(1), 1970
PMID: 4320461
Zubay G, Schwartz D, Beckwith J., Proc. Natl. Acad. Sci. U.S.A. 66(1), 1970
PMID: 4320461
Export
Markieren/ Markierung löschen
Markierte Publikationen
Web of Science
Dieser Datensatz im Web of Science®Quellen
PMID: 19665500
PubMed | Europe PMC
Suchen in
Google Scholar