A WD40-repeat gene from Malus x domestica is a functional homologue of Arabidopsis thaliana TRANSPARENT TESTA GLABRA1

Brueggemann J, Weisshaar B, Sagasser M (2010)
Plant Cell Reports 29(3): 285-294.

Zeitschriftenaufsatz | Veröffentlicht | Englisch
 
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DOI
Autor*in
Brueggemann, Julian; Weisshaar, BerndUniBi ; Sagasser, MartinUniBi
Einrichtung
Centrum für Biotechnologie > Arbeitsgruppe B. Weisshaar
Fakultät für Biologie > Genetik und Genomik der Pflanzen
Centrum für Biotechnologie > Institut für Genomforschung und Systembiologie
Abstract / Bemerkung
The WD40 repeat protein TRANSPARENT TESTA GLABRA1 (TTG1) is involved in a multitude of developmental and biochemical reactions in Arabidopsis thaliana such as the production of seed coat colour and mucilage, pigmentation by anthocyanins as well as the formation of trichomes and root hairs. In this study, a putative TTG1 homologue was isolated from apple (Malus x domestica Borkh.) showing 80.2% identity to A. thaliana TTG1 on nucleotide and 90.7% similarity on amino acid level. The MdTTG1 candidate was able to activate the AtBAN promoter in cooperation with the A. thaliana transcription factors TT2 and TT8 in A. thaliana protoplasts. This indicates that the encoded protein can be integrated into the complex that activates BAN in A. thaliana, and that a similar complex might also be present in apple. When transformed into ttg1 mutants of A. thaliana, the apple sequence was able to restore trichome growth, anthocyanin production in young seedlings as well as proanthocyanidin production in seeds. Additionally, roots of complemented mutant plants showed root hair formation resembling wild type. These results show that the studied apple WD40 gene is a functional homologue of AtTTG1 and we refer to this gene as MdTTG1.
Stichworte
WD-repeat; Complementation; Proanthocyanidins; Apple; TTG1
Erscheinungsjahr
2010
Zeitschriftentitel
Plant Cell Reports
Band
29
Ausgabe
3
Seite(n)
285-294
ISSN
0721-7714
eISSN
1432-203X
Page URI
https://pub.uni-bielefeld.de/record/1588513

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Brueggemann J, Weisshaar B, Sagasser M. A WD40-repeat gene from Malus x domestica is a functional homologue of Arabidopsis thaliana TRANSPARENT TESTA GLABRA1. Plant Cell Reports. 2010;29(3):285-294.
Brueggemann, J., Weisshaar, B., & Sagasser, M. (2010). A WD40-repeat gene from Malus x domestica is a functional homologue of Arabidopsis thaliana TRANSPARENT TESTA GLABRA1. Plant Cell Reports, 29(3), 285-294. https://doi.org/10.1007/s00299-010-0821-0
Brueggemann, Julian, Weisshaar, Bernd, and Sagasser, Martin. 2010. “A WD40-repeat gene from Malus x domestica is a functional homologue of Arabidopsis thaliana TRANSPARENT TESTA GLABRA1”. Plant Cell Reports 29 (3): 285-294.
Brueggemann, J., Weisshaar, B., and Sagasser, M. (2010). A WD40-repeat gene from Malus x domestica is a functional homologue of Arabidopsis thaliana TRANSPARENT TESTA GLABRA1. Plant Cell Reports 29, 285-294.
Brueggemann, J., Weisshaar, B., & Sagasser, M., 2010. A WD40-repeat gene from Malus x domestica is a functional homologue of Arabidopsis thaliana TRANSPARENT TESTA GLABRA1. Plant Cell Reports, 29(3), p 285-294.
J. Brueggemann, B. Weisshaar, and M. Sagasser, “A WD40-repeat gene from Malus x domestica is a functional homologue of Arabidopsis thaliana TRANSPARENT TESTA GLABRA1”, Plant Cell Reports, vol. 29, 2010, pp. 285-294.
Brueggemann, J., Weisshaar, B., Sagasser, M.: A WD40-repeat gene from Malus x domestica is a functional homologue of Arabidopsis thaliana TRANSPARENT TESTA GLABRA1. Plant Cell Reports. 29, 285-294 (2010).
Brueggemann, Julian, Weisshaar, Bernd, and Sagasser, Martin. “A WD40-repeat gene from Malus x domestica is a functional homologue of Arabidopsis thaliana TRANSPARENT TESTA GLABRA1”. Plant Cell Reports 29.3 (2010): 285-294.

27 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Identification and Characterization of Anthocyanin Biosynthesis-Related Genes in Kohlrabi.
Rahim MA, Robin AHK, Natarajan S, Jung HJ, Lee J, Kim H, Kim HT, Park JI, Nou IS., Appl Biochem Biotechnol 184(4), 2018
PMID: 28965308
The effect of promoter methylation on MdMYB1 expression determines the level of anthocyanin accumulation in skins of two non-red apple cultivars.
Ma C, Jing C, Chang B, Yan J, Liang B, Liu L, Yang Y, Zhao Z., BMC Plant Biol 18(1), 2018
PMID: 29871614
Genome-wide characterization, identification, and expression analysis of the WD40 protein family in cotton.
Salih H, Gong W, Mkulama M, Du X., Genome 61(7), 2018
PMID: 29852082
MdHIR proteins repress anthocyanin accumulation by interacting with the MdJAZ2 protein to inhibit its degradation in apples.
Chen KQ, Zhao XY, An XH, Tian Y, Liu DD, You CX, Hao YJ., Sci Rep 7(), 2017
PMID: 28317851
The influence of postharvest UV-C treatment on anthocyanin biosynthesis in fresh-cut red cabbage.
Wu J, Liu W, Yuan L, Guan WQ, Brennan CS, Zhang YY, Zhang J, Wang ZD., Sci Rep 7(1), 2017
PMID: 28701702
Expression Differences of Pigment Structural Genes and Transcription Factors Explain Flesh Coloration in Three Contrasting Kiwifruit Cultivars.
Liu Y, Zhou B, Qi Y, Chen X, Liu C, Liu Z, Ren X., Front Plant Sci 8(), 2017
PMID: 28919902
TRANSPARENT TESTA GLABRA 1-Dependent Regulation of Flavonoid Biosynthesis.
Zhang B, Schrader A., Plants (Basel) 6(4), 2017
PMID: 29261137
The R2R3 MYB transcription factor PavMYB10.1 involves in anthocyanin biosynthesis and determines fruit skin colour in sweet cherry (Prunus avium L.).
Jin W, Wang H, Li M, Wang J, Yang Y, Zhang X, Yan G, Zhang H, Liu J, Zhang K., Plant Biotechnol J 14(11), 2016
PMID: 27107393
Pathways involved in vanadate-induced root hair formation in Arabidopsis.
Lin CY, Huang LY, Chi WC, Huang TL, Kakimoto T, Tsai CR, Huang HJ., Physiol Plant 153(1), 2015
PMID: 24833217
Ternary WD40 Repeat-Containing Protein Complexes: Evolution, Composition and Roles in Plant Immunity.
Miller JC, Chezem WR, Clay NK., Front Plant Sci 6(), 2015
PMID: 26779203
Pathways involved in vanadate‐induced root hair formation in Arabidopsis
Lin C, Huang L, Chi W, Huang T, Kakimoto T, Tsai C, Huang H., Physiol Plant 153(1), 2015
PMID: IND601259753
Molecular characterization of genes encoding leucoanthocyanidin reductase involved in proanthocyanidin biosynthesis in apple.
Liao L, Vimolmangkang S, Wei G, Zhou H, Korban SS, Han Y., Front Plant Sci 6(), 2015
PMID: 25914714
Analysis of TTG1 function in Arabis alpina.
Chopra D, Wolff H, Span J, Schellmann S, Coupland G, Albani MC, Schrader A, Hülskamp M., BMC Plant Biol 14(), 2014
PMID: 24406039
Cloning and characterization of a potato StAN11 gene involved in anthocyanin biosynthesis regulation.
Li W, Wang B, Wang M, Chen M, Yin JM, Kaleri GM, Zhang RJ, Zuo TN, You X, Yang Q., J Integr Plant Biol 56(4), 2014
PMID: 24304603
Regulation of anthocyanin biosynthesis in peach fruits.
Rahim MA, Busatto N, Trainotti L., Planta 240(5), 2014
PMID: 24827911
bHLH05 is an interaction partner of MYB51 and a novel regulator of glucosinolate biosynthesis in Arabidopsis.
Frerigmann H, Berger B, Gigolashvili T., Plant Physiol 166(1), 2014
PMID: 25049362
An ancient duplication of apple MYB transcription factors is responsible for novel red fruit-flesh phenotypes.
Chagné D, Lin-Wang K, Espley RV, Volz RK, How NM, Rouse S, Brendolise C, Carlisle CM, Kumar S, De Silva N, Micheletti D, McGhie T, Crowhurst RN, Storey RD, Velasco R, Hellens RP, Gardiner SE, Allan AC., Plant Physiol 161(1), 2013
PMID: 23096157
The R2R3-MYB, bHLH, WD40, and related transcription factors in flavonoid biosynthesis.
Zhao L, Gao L, Wang H, Chen X, Wang Y, Yang H, Wei C, Wan X, Xia T., Funct Integr Genomics 13(1), 2013
PMID: 23184474
Fruit coloration and anthocyanin biosynthesis after bag removal in non-red and red apples (Malus × domestica Borkh.).
Liu Y, Che F, Wang L, Meng R, Zhang X, Zhao Z., Molecules 18(2), 2013
PMID: 23353125
New insights into the regulation of anthocyanin biosynthesis in fruits.
Jaakola L., Trends Plant Sci 18(9), 2013
PMID: 23870661
Genetic analysis of metabolites in apple fruits indicates an mQTL hotspot for phenolic compounds on linkage group 16.
Khan SA, Chibon PY, de Vos RC, Schipper BA, Walraven E, Beekwilder J, van Dijk T, Finkers R, Visser RG, van de Weg EW, Bovy A, Cestaro A, Velasco R, Jacobsen E, Schouten HJ., J Exp Bot 63(8), 2012
PMID: 22330898
Transcriptional analysis of apple fruit proanthocyanidin biosynthesis.
Henry-Kirk RA, McGhie TK, Andre CM, Hellens RP, Allan AC., J Exp Bot 63(15), 2012
PMID: 22859681
Evolutionary and comparative analysis of MYB and bHLH plant transcription factors.
Feller A, Machemer K, Braun EL, Grotewold E., Plant J 66(1), 2011
PMID: 21443626
High temperature reduces apple fruit colour via modulation of the anthocyanin regulatory complex.
Lin-Wang K, Micheletti D, Palmer J, Volz R, Lozano L, Espley R, Hellens RP, Chagnè D, Rowan DD, Troggio M, Iglesias I, Allan AC., Plant Cell Environ 34(7), 2011
PMID: 21410713
A genomic approach to study anthocyanin synthesis and flower pigmentation in passionflowers.
Aizza LC, Dornelas MC., J Nucleic Acids 2011(), 2011
PMID: 21772993
A pomegranate (Punica granatum L.) WD40-repeat gene is a functional homologue of Arabidopsis TTG1 and is involved in the regulation of anthocyanin biosynthesis during pomegranate fruit development.
Ben-Simhon Z, Judeinstein S, Nadler-Hassar T, Trainin T, Bar-Ya'akov I, Borochov-Neori H, Holland D., Planta 234(5), 2011
PMID: 21643990
Weird fingers: functional analysis of WIP domain proteins.
Appelhagen I, Huep G, Lu GH, Strompen G, Weisshaar B, Sagasser M., FEBS Lett 584(14), 2010
PMID: 20541552

43 References

Daten bereitgestellt von Europe PubMed Central.

Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract.
Bagchi D, Sen CK, Ray SD, Das DK, Bagchi M, Preuss HG, Vinson JA., Mutat. Res. 523-524(), 2003
PMID: 12628506
Isolation and functional analysis of a MYB transcription factor gene that is a key regulator for the development of red coloration in apple skin.
Ban Y, Honda C, Hatsuyama Y, Igarashi M, Bessho H, Moriguchi T., Plant Cell Physiol. 48(7), 2007
PMID: 17526919
TT2, TT8, and TTG1 synergistically specify the expression of BANYULS and proanthocyanidin biosynthesis in Arabidopsis thaliana.
Baudry A, Heim MA, Dubreucq B, Caboche M, Weisshaar B, Lepiniec L., Plant J. 39(3), 2004
PMID: 15255866
Activation tagging identifies a conserved MYB regulator of phenylpropanoid biosynthesis.
Borevitz JO, Xia Y, Blount J, Dixon RA, Lamb C., Plant Cell 12(12), 2000
PMID: 11148285
Mutations in the pale aleurone color1 regulatory gene of the Zea mays anthocyanin pathway have distinct phenotypes relative to the functionally similar TRANSPARENT TESTA GLABRA1 gene in Arabidopsis thaliana.
Carey CC, Strahle JT, Selinger DA, Chandler VL., Plant Cell 16(2), 2004
PMID: 14742877
Isolation of a cDNA Clone (Accession No. AF195869) Encoding Mitochondrial Malate Dehydrogenase from Grape (Vitis vinifera cv. Perlette) Developing Fruits (PGR00-045).
Or E, Baybik J, Sacks Y, Vilozny I., Plant Physiol. 122(4), 2000
PMID: c1967
Mapping a candidate gene (MdMYB10) for red flesh and foliage colour in apple.
Chagne D, Carlisle CM, Blond C, Volz RK, Whitworth CJ, Oraguzie NC, Crowhurst RN, Allan AC, Espley RV, Hellens RP, Gardiner SE., BMC Genomics 8(), 2007
PMID: 17608951
Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana.
Clough SJ, Bent AF., Plant J. 16(6), 1998
PMID: 10069079
A review of the health effects of green tea catechins in in vivo animal models.
Crespy V, Williamson G., J. Nutr. 134(12 Suppl), 2004
PMID: 15570050
The an11 locus controlling flower pigmentation in petunia encodes a novel WD-repeat protein conserved in yeast, plants, and animals.
de Vetten N, Quattrocchio F, Mol J, Koes R., Genes Dev. 11(11), 1997
PMID: 9192870
Influence of the testa on seed dormancy, germination, and longevity in Arabidopsis.
Debeaujon I, Leon-Kloosterziel KM, Koornneef M., Plant Physiol. 122(2), 2000
PMID: 10677433

A, Plant Biol 11(), 2009
Red colouration in apple fruit is due to the activity of the MYB transcription factor, MdMYB10.
Espley RV, Hellens RP, Putterill J, Stevenson DE, Kutty-Amma S, Allan AC., Plant J. 49(3), 2006
PMID: 17181777
Functional analysis of a light-responsive plant bZIP transcriptional regulator.
Feldbrugge M, Sprenger M, Dinkelbach M, Yazaki K, Harter K, Weisshaar B., Plant Cell 6(11), 1994
PMID: 7827494
The TTG gene is required to specify epidermal cell fate and cell patterning in the Arabidopsis root.
Galway ME, Masucci JD, Lloyd AM, Walbot V, Davis RW, Schiefelbein JW., Dev. Biol. 166(2), 1994
PMID: 7813791

K, Plant Mol Biol Rep 22(), 2004

C, Plant Physiol Biochem 40(), 2002
Two WD-repeat genes from cotton are functional homologues of the Arabidopsis thaliana TRANSPARENT TESTA GLABRA1 (TTG1) gene.
Humphries JA, Walker AR, Timmis JN, Orford SJ., Plant Mol. Biol. 57(1), 2005
PMID: 15821869

C, Mol Gen Genet 204(), 1986

M, Arabidopsis Inf Serv 18(), 1981
Clustal W and Clustal X version 2.0.
Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, McWilliam H, Valentin F, Wallace IM, Wilm A, Lopez R, Thompson JD, Gibson TJ, Higgins DG., Bioinformatics 23(21), 2007
PMID: 17846036
Genetics and biochemistry of seed flavonoids.
Lepiniec L, Debeaujon I, Routaboul JM, Baudry A, Pourcel L, Nesi N, Caboche M., Annu Rev Plant Biol 57(), 2006
PMID: 16669768
New perspectives on proanthocyanidin biochemistry and molecular regulation.
Marles MA, Ray H, Gruber MY., Phytochemistry 64(2), 2003
PMID: 12943753
The Arabidopsis transcription factor MYB12 is a flavonol-specific regulator of phenylpropanoid biosynthesis.
Mehrtens F, Kranz H, Bednarek P, Weisshaar B., Plant Physiol. 138(2), 2005
PMID: 15923334

T, Plant Physiol 15(), 1962
PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization.
Nakai K, Horton P., Trends Biochem. Sci. 24(1), 1999
PMID: 10087920
The TT8 gene encodes a basic helix-loop-helix domain protein required for expression of DFR and BAN genes in Arabidopsis siliques.
Nesi N, Debeaujon I, Jond C, Pelletier G, Caboche M, Lepiniec L., Plant Cell 12(10), 2000
PMID: 11041882
A WD40 repeat protein from Medicago truncatula is necessary for tissue-specific anthocyanin and proanthocyanidin biosynthesis but not for trichome development.
Pang Y, Wenger JP, Saathoff K, Peel GJ, Wen J, Huhman D, Allen SN, Tang Y, Cheng X, Tadege M, Ratet P, Mysore KS, Sumner LW, Marks MD, Dixon RA., Plant Physiol. 151(3), 2009
PMID: 19710231
Concentrations and characteristics of procyanidins and other phenolics in apples during fruit growth.
Renard CM, Dupont N, Guillermin P., Phytochemistry 68(8), 2007
PMID: 17400262
Extraction of DNA from milligram amounts of fresh, herbarium and mummified plant tissues.
Rogers SO, Bendich AJ., Plant Mol. Biol. 5(2), 1985
PMID: 24306565

J, 1989
A WD-repeat-containing putative regulatory protein in anthocyanin biosynthesis in Perilla frutescens.
Sompornpailin K, Makita Y, Yamazaki M, Saito K., Plant Mol. Biol. 50(3), 2002
PMID: 12369624
Transactivation properties of parsley proline-rich bZIP transcription factors.
Sprenger-Haussels M, Weisshaar B., Plant J. 22(1), 2000
PMID: 10792815
Differential regulation of closely related R2R3-MYB transcription factors controls flavonol accumulation in different parts of the Arabidopsis thaliana seedling.
Stracke R, Ishihara H, Huep G, Barsch A, Mehrtens F, Niehaus K, Weisshaar B., Plant J. 50(4), 2007
PMID: 17419845
Structural analysis based on state-space modeling.
Stultz CM, White JV, Smith TF., Protein Sci. 2(3), 1993
PMID: 8453370
Light-induced expression of a MYB gene regulates anthocyanin biosynthesis in red apples.
Takos AM, Jaffe FW, Jacob SR, Bogs J, Robinson SP, Walker AR., Plant Physiol. 142(3), 2006
PMID: 17012405
TREECON for Windows: a software package for the construction and drawing of evolutionary trees for the Microsoft Windows environment.
Van de Peer Y, De Wachter R., Comput. Appl. Biosci. 10(5), 1994
PMID: 7828077
The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in Arabidopsis, encodes a WD40 repeat protein.
Walker AR, Davison PA, Bolognesi-Winfield AC, James CM, Srinivasan N, Blundell TL, Esch JJ, Marks MD, Gray JC., Plant Cell 11(7), 1999
PMID: 10402433
Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology.
Winkel-Shirley B., Plant Physiol. 126(2), 2001
PMID: 11402179
Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis.
Xie DY, Sharma SB, Paiva NL, Ferreira D, Dixon RA., Science 299(5605), 2003
PMID: 12532018
Map-based cloning and characterization of a gene controlling hairiness and seed coat color traits in Brassica rapa.
Zhang J, Lu Y, Yuan Y, Zhang X, Geng J, Chen Y, Cloutier S, McVetty PB, Li G., Plant Mol. Biol. 69(5), 2008
PMID: 19039665
The TTG1-bHLH-MYB complex controls trichome cell fate and patterning through direct targeting of regulatory loci.
Zhao M, Morohashi K, Hatlestad G, Grotewold E, Lloyd A., Development 135(11), 2008
PMID: 18434419
Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.
Zimmermann IM, Heim MA, Weisshaar B, Uhrig JF., Plant J. 40(1), 2004
PMID: 15361138
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