Cognitive performance of detoxified alcoholic Korsakoff syndrome patients remains stable over two years

Fujiwara E, Brand M, Borsutzky S, Steingass H-P, Markowitsch HJ (2008)
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY 30(5): 576-587.

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Abstract / Bemerkung
Excessive alcohol consumption is assumed to promote cognitive decline, eventually increasing the risk of dementia. However, little is known about the time course of cognitive functions in patients with chronic alcoholic Korsakoff syndrome (KS). Therefore, we assessed neuropsychological performance in 20 detoxified chronic KS inpatients at time 1 (T1) with a follow-up after two years (T2). The neuropsychological tests assessed verbal and visual short- and long-term memory, working memory, basic executive functions, language, general knowledge, and visual-spatial abilities. Surveys with caregivers and medical records provided information about current and previous disease-related parameters, drinking history, additional pathologies, as well as psychosocial and cognitive therapy within the two-year period. At both sessions, the majority of the KS patients' results were inferior to those of normal subjects. Comparing T1 and T2 revealed no significant decline in any of the investigated functions. Instead, general knowledge, visual long-term memory, and verbal fluency improved slightly after two years, though they still remained within pathological range. Comparing most improved and most deteriorated patients, better outcome occurred more frequently in men than women and was associated with higher premorbid education and fewer detoxifications in the past. In this sample of detoxified KS patients there was no indication of accelerated cognitive decline or onset of dementia-like symptoms over two years.
Erscheinungsjahr
2008
Zeitschriftentitel
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY
Band
30
Ausgabe
5
Seite(n)
576-587
ISSN
1380-3395
eISSN
1744-411X
Page URI
https://pub.uni-bielefeld.de/record/1587254

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Fujiwara E, Brand M, Borsutzky S, Steingass H-P, Markowitsch HJ. Cognitive performance of detoxified alcoholic Korsakoff syndrome patients remains stable over two years. JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY. 2008;30(5):576-587.
Fujiwara, E., Brand, M., Borsutzky, S., Steingass, H. - P., & Markowitsch, H. J. (2008). Cognitive performance of detoxified alcoholic Korsakoff syndrome patients remains stable over two years. JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, 30(5), 576-587. https://doi.org/10.1080/13803390701557271
Fujiwara, Esther, Brand, Matthias, Borsutzky, Sabine, Steingass, Hans-P., and Markowitsch, Hans J. 2008. “Cognitive performance of detoxified alcoholic Korsakoff syndrome patients remains stable over two years”. JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY 30 (5): 576-587.
Fujiwara, E., Brand, M., Borsutzky, S., Steingass, H. - P., and Markowitsch, H. J. (2008). Cognitive performance of detoxified alcoholic Korsakoff syndrome patients remains stable over two years. JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY 30, 576-587.
Fujiwara, E., et al., 2008. Cognitive performance of detoxified alcoholic Korsakoff syndrome patients remains stable over two years. JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, 30(5), p 576-587.
E. Fujiwara, et al., “Cognitive performance of detoxified alcoholic Korsakoff syndrome patients remains stable over two years”, JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, vol. 30, 2008, pp. 576-587.
Fujiwara, E., Brand, M., Borsutzky, S., Steingass, H.-P., Markowitsch, H.J.: Cognitive performance of detoxified alcoholic Korsakoff syndrome patients remains stable over two years. JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY. 30, 576-587 (2008).
Fujiwara, Esther, Brand, Matthias, Borsutzky, Sabine, Steingass, Hans-P., and Markowitsch, Hans J. “Cognitive performance of detoxified alcoholic Korsakoff syndrome patients remains stable over two years”. JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY 30.5 (2008): 576-587.

16 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Imbalance between cognitive systems in alcohol-dependence and Korsakoff syndrome: An exploration using the Alcohol Flanker Task.
Brion M, Dormal V, Lannoy S, Mertens S, de Timary P, Maurage P., J Clin Exp Neuropsychol 40(8), 2018
PMID: 29509075
Differential spontaneous recovery across cognitive abilities during detoxification period in alcohol-dependence.
Petit G, Luminet O, Cordovil de Sousa Uva M, Zorbas A, Maurage P, de Timary P., PLoS One 12(8), 2017
PMID: 28767647
Crossmodal processing of emotions in alcohol-dependence and Korsakoff syndrome.
Brion M, D'Hondt F, Lannoy S, Pitel AL, Davidoff DA, Maurage P., Cogn Neuropsychiatry 22(5), 2017
PMID: 28885888
Korsakoff's syndrome: a critical review.
Arts NJ, Walvoort SJ, Kessels RP., Neuropsychiatr Dis Treat 13(), 2017
PMID: 29225466
Salient cues improve prospective remembering in Korsakoff's syndrome.
Altgassen M, Ariese L, Wester AJ, Kessels RP., Br J Clin Psychol 55(2), 2016
PMID: 26577704
Comprehensive assessment of alcohol-related brain damage (ARBD): gap or chasm in the evidence?
Horton L, Duffy T, Hollins Martin C, Martin CR., J Psychiatr Ment Health Nurs 22(1), 2015
PMID: 24846298
A Case of Chronic Wernicke's Encephalopathy: A Neuropsychological Study.
Oudman E, Van der Stigchel S, Postma A, Wijnia JW, Nijboer TC., Front Psychiatry 5(), 2014
PMID: 24904442
Revisiting the continuum hypothesis: toward an in-depth exploration of executive functions in korsakoff syndrome.
Brion M, Pitel AL, Beaunieux H, Maurage P., Front Hum Neurosci 8(), 2014
PMID: 25071526
Recovery of neurocognitive functions following sustained abstinence after substance dependence and implications for treatment.
Schulte MH, Cousijn J, den Uyl TE, Goudriaan AE, van den Brink W, Veltman DJ, Schilt T, Wiers RW., Clin Psychol Rev 34(7), 2014
PMID: 25240109
Alcohol-related dementia: an update of the evidence.
Ridley NJ, Draper B, Withall A., Alzheimers Res Ther 5(1), 2013
PMID: 23347747
Executive functioning in chronic alcoholism and Korsakoff syndrome.
Maharasingam M, Macniven JA, Mason OJ., J Clin Exp Neuropsychol 35(5), 2013
PMID: 23656524
Memory and self-neuroscientific landscapes.
Markowitsch HJ., ISRN Neurosci 2013(), 2013
PMID: 24967303
Antisaccade performance in Korsakoff patients reveals deficits in oculomotor inhibition.
Van der Stigchel S, Reichenbach RC, Wester AJ, Nijboer TC., J Clin Exp Neuropsychol 34(8), 2012
PMID: 22712532

77 References

Daten bereitgestellt von Europe PubMed Central.

Temporal gradients in the retrograde amnesia of patients with alcoholic Korsakoff's disease.
Albert MS, Butters N, Levin J., Arch. Neurol. 36(4), 1979
PMID: 426664

Anttila, 2004

American, 1994
Cognitive estimation and affective judgments in alcoholic Korsakoff patients.
Brand M, Fujiwara E, Kalbe E, Steingass HP, Kessler J, Markowitsch HJ., J Clin Exp Neuropsychol 25(3), 2003
PMID: 12916646
Cognitive loss and recovery in long-term alcohol abusers.
Brandt J, Butters N, Ryan C, Bayog R., Arch. Gen. Psychiatry 40(4), 1983
PMID: 6838323
Frontal lobe dysfunctions in Korsakoff's syndrome and chronic alcoholism: continuity or discontinuity?
Brokate B, Hildebrandt H, Eling P, Fichtner H, Runge K, Timm C., Neuropsychology 17(3), 2003
PMID: 12959508
Material-specific memory deficits in alcoholic Korsakoff patients.
Butters N, Lewis R, Cermak LS, Goodglass H., Neuropsychologia 11(3), 1973
PMID: 4792180
Smoking, drinking, and incident cognitive impairment: a cohort community based study included in the Gospel Oak project.
Cervilla JA, Prince M, Mann A., J. Neurol. Neurosurg. Psychiatry 68(5), 2000
PMID: 10766894

AUTHOR UNKNOWN, 0
Interaction of nutrition and binge ethanol treatment on brain damage and withdrawal.
Crews FT, Braun CJ, Ali R, Knapp DJ., J. Biomed. Sci. 8(1), 2001
PMID: 11173987

Cutting, British Journal of Psychiatry 132(), 1978

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0
Impairment in cognitive functions after multiple detoxifications in alcoholic inpatients.
Duka T, Townshend JM, Collier K, Stephens DN., Alcohol. Clin. Exp. Res. 27(10), 2003
PMID: 14574226
Cortisol dysregulation and cognitive impairment in abstinent male alcoholics.
Errico AL, King AC, Lovallo WR, Parsons OA., Alcohol. Clin. Exp. Res. 26(8), 2002
PMID: 12198394
"Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.
Folstein MF, Folstein SE, McHugh PR., J Psychiatr Res 12(3), 1975
PMID: 1202204
Addiction changes orbitofrontal gyrus function: involvement in response inhibition.
Goldstein RZ, Volkow ND, Wang GJ, Fowler JS, Rajaram S., Neuroreport 12(11), 2001
PMID: 11496155
Degeneration of anterior thalamic nuclei differentiates alcoholics with amnesia.
Harding A, Halliday G, Caine D, Kril J., Brain 123 ( Pt 1)(), 2000
PMID: 10611128

Härting, 2000

Hommer, Alcohol Research and Health 27(), 2003

Horvath, 1975
Effects of closed traumatic brain injury and genetic factors on the development of Alzheimer's disease.
Jellinger KA, Paulus W, Wrocklage C, Litvan I., Eur. J. Neurol. 8(6), 2001
PMID: 11784357

Kessler, 1990

AUTHOR UNKNOWN, 0
The Korsakoff syndrome.
Kopelman MD., Br J Psychiatry 166(2), 1995
PMID: 7728359
Retrograde amnesia in patients with diencephalic, temporal lobe or frontal lesions.
Kopelman MD, Stanhope N, Kingsley D., Neuropsychologia 37(8), 1999
PMID: 10426519
Environmental influences on cognitive and brain plasticity during aging.
Kramer AF, Bherer L, Colcombe SJ, Dong W, Greenough WT., J. Gerontol. A Biol. Sci. Med. Sci. 59(9), 2004
PMID: 15472160
The cerebral cortex is damaged in chronic alcoholics.
Kril JJ, Halliday GM, Svoboda MD, Cartwright H., Neuroscience 79(4), 1997
PMID: 9219961

Lehrl, 1991
Alcohol and the brain.
Lishman WA., Br J Psychiatry 156(), 1990
PMID: 2099160
Rapid recovery from cognitive deficits in abstinent alcoholics: a controlled test-retest study.
Mann K, Gunther A, Stetter F, Ackermann K., Alcohol Alcohol. 34(4), 1999
PMID: 10456585
Neuroimaging in alcoholism: CT and MRI results and clinical correlates.
Mann K, Mundle G, Strayle M, Wakat P., J. Neural Transm. Gen. Sect. 99(1-3), 1995
PMID: 8579801
Risk factors for cerebral degenerative changes and dementia.
Meyer JS, Terayama Y, Konno S, Akiyama H, Margishvili GM, Mortel KF., Eur. Neurol. 39 Suppl 1(), 1998
PMID: 9516069

Modrego, Annals of Neurology 61(), 2004
Prospective study of alcohol consumption and risk of dementia in older adults.
Mukamal KJ, Kuller LH, Fitzpatrick AL, Longstreth WT Jr, Mittleman MA, Siscovick DS., JAMA 289(11), 2003
PMID: 12636463

Nelson, 1982
Brain impairment in well-nourished chronic alcoholics is related to ethanol intake.
Nicolas JM, Estruch R, Salamero M, Orteu N, Fernandez-Sola J, Sacanella E, Urbano-Marquez A., Ann. Neurol. 41(5), 1997
PMID: 9153520
Alcohol related dementia: proposed clinical criteria.
Oslin D, Atkinson RM, Smith DM, Hendrie H., Int J Geriatr Psychiatry 13(4), 1998
PMID: 9646147

Osterrieth, Archives de Psychologie 30(), 1944

Oswald, 1997
Neurobehavioral sequelae of alcoholism.
Parsons OA, Nixon SJ., Neurol Clin 11(1), 1993
PMID: 8441371
Do women possess a unique susceptibility to the neurotoxic effects of alcohol?
Prendergast MA., J Am Med Womens Assoc (1972) 59(3), 2004
PMID: 15354377
Putative tests of frontal lobe function: a PET-study of brain activation during Stroop's Test and verbal fluency.
Ravnkilde B, Videbech P, Rosenberg R, Gjedde A, Gade A., J Clin Exp Neuropsychol 24(4), 2002
PMID: 12187466
FDG-PET findings in the Wernicke-Korsakoff syndrome.
Reed LJ, Lasserson D, Marsden P, Stanhope N, Stevens T, Bello F, Kingsley D, Colchester A, Kopelman MD., Cortex 39(4-5), 2003
PMID: 14584565
Effect of vascular lesions on cognition in Alzheimer's disease: a community-based study.
Riekse RG, Leverenz JB, McCormick W, Bowen JD, Teri L, Nochlin D, Simpson K, Eugenio C, Larson EB, Tsuang D., J Am Geriatr Soc 52(9), 2004
PMID: 15341544
Selective deficits in appetitive conditioning as a consequence of ethanol withdrawal.
Ripley TL, Borlikova G, Lyons S, Stephens DN., Eur. J. Neurosci. 19(2), 2004
PMID: 14725636
Effects of a history of heavy alcohol consumption on Alzheimer's disease.
Rosen J, Colantonio A, Becker JT, Lopez OL, DeKosky ST, Moss HB., Br J Psychiatry 163(), 1993
PMID: 8401966

Ryback, Quarterly Journal of Studies in Alcoholism 32(), 1971

AUTHOR UNKNOWN, 0
Heavy drinking as a risk factor for depression and dementia in elderly men. Findings from the Liverpool longitudinal community study.
Saunders PA, Copeland JR, Dewey ME, Davidson IA, McWilliam C, Sharma V, Sullivan C., Br J Psychiatry 159(), 1991
PMID: 1773236

Schaaf, 1992

Siebert, Allgemeine Zeitschrift für Psychiatrie 99(), 1933

Spreen, 1998

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0
The effects of focal anterior and posterior brain lesions on verbal fluency.
Stuss DT, Alexander MP, Hamer L, Palumbo C, Dempster R, Binns M, Levine B, Izukawa D., J Int Neuropsychol Soc 4(3), 1998
PMID: 9623001

Talland, 1965
Cognitive deterioration in Alzheimer's disease: behavioral and health factors.
Teri L, Hughes JP, Larson EB., J Gerontol 45(2), 1990
PMID: 2313049

Tewes, 1991
Alcohol abuse, cognitive impairment, and mortality among older people.
Thomas VS, Rockwood KJ., J Am Geriatr Soc 49(4), 2001
PMID: 11347785
Significant reversibility of alcoholic brain shrinkage within 3 weeks of abstinence.
Trabert W, Betz T, Niewald M, Huber G., Acta Psychiatr Scand 92(2), 1995
PMID: 7572265
Repeated ethanol withdrawal delays development of focal seizures in hippocampal kindling.
Veatch LM, Gonzalez LP., Alcohol. Clin. Exp. Res. 23(7), 1999
PMID: 10443979
Alcoholic dementia.
Victor M., Can J Neurol Sci 21(2), 1994
PMID: 8087744

Victor, 1989

World, 1994
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