Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children

Kalbe E, Brand M, Thiel A, Kessler J, Markowitsch HJ (2008)
NEUROCASE 14(1): 15-28.

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Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Abstract / Bemerkung
We report a case of a delusional patient who had killed two of her children in an attempted 'extended suicide'. She was convinced of a genetic defect that caused autobiographical memory and emotional deficits and made life 'senseless'. Neuropsychological tests revealed dysfunctions in remembering emotional details of personal episodes and theory of mind. Water positron emission tomography (O-15) with a paradigm used in a former study by Fink et al. (1996) with healthy controls elicited abnormal activations during autobiographical memory retrieval characterised by a lack of prefrontal and limbic activity. We conclude that these imaging findings reflect neural correlates of the self-reported and objectified autobiographical dysfunctions. Furthermore, they indicate that beliefs or prejudices may have a major impact on the brain's processing of the personal past.
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Kalbe E, Brand M, Thiel A, Kessler J, Markowitsch HJ. Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children. NEUROCASE. 2008;14(1):15-28.
Kalbe, E., Brand, M., Thiel, A., Kessler, J., & Markowitsch, H. J. (2008). Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children. NEUROCASE, 14(1), 15-28. doi:10.1080/13554790801992735
Kalbe, E., Brand, M., Thiel, A., Kessler, J., and Markowitsch, H. J. (2008). Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children. NEUROCASE 14, 15-28.
Kalbe, E., et al., 2008. Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children. NEUROCASE, 14(1), p 15-28.
E. Kalbe, et al., “Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children”, NEUROCASE, vol. 14, 2008, pp. 15-28.
Kalbe, E., Brand, M., Thiel, A., Kessler, J., Markowitsch, H.J.: Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children. NEUROCASE. 14, 15-28 (2008).
Kalbe, E., Brand, M., Thiel, A., Kessler, J., and Markowitsch, Hans J. “Neuropsychological and neural correlates of autobiographical deficits in a mother who killed her children”. NEUROCASE 14.1 (2008): 15-28.

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