Compact fs ytterbium fiber laser at 1010 nm for biomedical applications

Kong C, Pilger C, Hachmeister H, Wei X, Cheung TH, Lai CSW, Huser T, Tsia KK, Wong KKY (2017)
BIOMEDICAL OPTICS EXPRESS 8(11): 4921-4932.

Download
No fulltext has been uploaded. References only!
Journal Article | Original Article | Published | English

No fulltext has been uploaded

Author
; ; ; ; ; ; ; ;
Abstract
Ytterbium-doped fiber lasers (YDFLs) working in the near-infrared (NIR) spectral window and capable of high-power operation are popular in recent years. They have been broadly used in a variety of scientific and industrial research areas, including light bullet generation, optical frequency comb formation, materials fabrication, free-space laser communication, and biomedical diagnostics as well. The growing interest in YDFLs has also been cultivated for the generation of high-power femtosecond (fs) pulses. Unfortunately, the operating wavelengths of fs YDFLs have mostly been confined to two spectral bands, i.e., 970-980 nm through the three-level energy transition and 1030-1100 nm through the quasi three-level energy transition, leading to a spectral gap (990-1020 nm) in between, which is attributed to an intrinsically weak gain in this wavelength range. Here we demonstrate a high-power mode-locked fs YDFL operating at 1010 nm, which is accomplished in a compact and cost-effective package. It exhibits superior performance in terms of both short-term and long-term stability, i.e., <0.3% (peak intensity over 2.4 mu s) and < 4.0% (average power over 24 hours), respectively. To illustrate the practical applications, it is subsequently employed as a versatile fs laser for high-quality nonlinear imaging of biological samples, including two-photon excited fluorescence microscopy of mouse kidney and brain sections, as well as polarization-sensitive second-harmonic generation microscopy of potato starch granules and mouse tail muscle. It is anticipated that these efforts will largely extend the capability of fs YDFLs which is continuously tunable over 970-1100 nm wavelength range for wideband hyperspectral operations, serving as a promising complement to the gold-standard Ti: sapphire fs lasers. (C) 2017 Optical Society of America
Publishing Year
ISSN
PUB-ID

Cite this

Kong C, Pilger C, Hachmeister H, et al. Compact fs ytterbium fiber laser at 1010 nm for biomedical applications. BIOMEDICAL OPTICS EXPRESS. 2017;8(11):4921-4932.
Kong, C., Pilger, C., Hachmeister, H., Wei, X., Cheung, T. H., Lai, C. S. W., Huser, T., et al. (2017). Compact fs ytterbium fiber laser at 1010 nm for biomedical applications. BIOMEDICAL OPTICS EXPRESS, 8(11), 4921-4932. doi:10.1364/BOE.8.004921
Kong, C., Pilger, C., Hachmeister, H., Wei, X., Cheung, T. H., Lai, C. S. W., Huser, T., Tsia, K. K., and Wong, K. K. Y. (2017). Compact fs ytterbium fiber laser at 1010 nm for biomedical applications. BIOMEDICAL OPTICS EXPRESS 8, 4921-4932.
Kong, C., et al., 2017. Compact fs ytterbium fiber laser at 1010 nm for biomedical applications. BIOMEDICAL OPTICS EXPRESS, 8(11), p 4921-4932.
C. Kong, et al., “Compact fs ytterbium fiber laser at 1010 nm for biomedical applications”, BIOMEDICAL OPTICS EXPRESS, vol. 8, 2017, pp. 4921-4932.
Kong, C., Pilger, C., Hachmeister, H., Wei, X., Cheung, T.H., Lai, C.S.W., Huser, T., Tsia, K.K., Wong, K.K.Y.: Compact fs ytterbium fiber laser at 1010 nm for biomedical applications. BIOMEDICAL OPTICS EXPRESS. 8, 4921-4932 (2017).
Kong, Cihang, Pilger, Christian, Hachmeister, Henning, Wei, Xiaoming, Cheung, Tom H., Lai, Cora S. W., Huser, Thomas, Tsia, Kevin. K., and Wong, Kenneth K. Y. “Compact fs ytterbium fiber laser at 1010 nm for biomedical applications”. BIOMEDICAL OPTICS EXPRESS 8.11 (2017): 4921-4932.
This data publication is cited in the following publications:
This publication cites the following data publications:

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 29188091
PubMed | Europe PMC

Search this title in

Google Scholar