Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis

Fernández-Natal I, Rodríguez-Lázaro D, Marrodán-Ciordia T, Sáez-Nieto JA, Valdezate S, Rodríguez-Pollán H, Tauch A, Soriano F (2016)
New Microbes and New Infections 14: 93-97.

Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Autor
; ; ; ; ; ; ;
Abstract / Bemerkung
Human infections associated with Corynebacterium kroppenstedtii are rarely reported, and this organism is usually described as antibiotic sensitive. Almost all published cases of C.kroppenstedtii infections have been associated with breast pathology in women and have been described in New Zealand, France, Canada, India and Japan. Here we describe the microbiologic characteristics of two strains isolated from two women diagnosed of granulomatous mastitis in Spain. One C.kroppenstedtii isolate was antibiotic sensitive while the other was multidrug resistant. Biochemical identification was possible using a wide battery of methods including API Coryne V2.0, API Strep, API NH, API NE, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA gene amplification and sequencing. Antimicrobial susceptibility to 28 antibiotics as determined by Etest showed one isolate being sensitive to benzylpenicillin, ciprofloxacin, moxifloxacin, gentamicin, vancomycin, clindamycin, tetracycline, linezolid and rifampin. The second isolate showed resistance to ciprofloxacin, moxifloxacin, clindamycin, tetracycline and rifampin. The multidrug-resistant isolate contained the erm(X), tet(W), cmx, aphA1-IAB, strAB and sul1 resistance genes known from the R plasmid pJA144188 of Corynebacterium resistens. These genes were absent in the genome of the antibiotic-sensitive isolate. This report confirms the tropism of this microorganism for women's breasts and presents the first description of a multidrug-resistant C.kroppenstedtii strain.
Erscheinungsjahr
Zeitschriftentitel
New Microbes and New Infections
Band
14
Seite
93-97
ISSN
PUB-ID

Zitieren

Fernández-Natal I, Rodríguez-Lázaro D, Marrodán-Ciordia T, et al. Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis. New Microbes and New Infections. 2016;14:93-97.
Fernández-Natal, I., Rodríguez-Lázaro, D., Marrodán-Ciordia, T., Sáez-Nieto, J. A., Valdezate, S., Rodríguez-Pollán, H., Tauch, A., et al. (2016). Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis. New Microbes and New Infections, 14, 93-97. doi:10.1016/j.nmni.2016.09.006
Fernández-Natal, I., Rodríguez-Lázaro, D., Marrodán-Ciordia, T., Sáez-Nieto, J. A., Valdezate, S., Rodríguez-Pollán, H., Tauch, A., and Soriano, F. (2016). Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis. New Microbes and New Infections 14, 93-97.
Fernández-Natal, I., et al., 2016. Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis. New Microbes and New Infections, 14, p 93-97.
I. Fernández-Natal, et al., “Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis”, New Microbes and New Infections, vol. 14, 2016, pp. 93-97.
Fernández-Natal, I., Rodríguez-Lázaro, D., Marrodán-Ciordia, T., Sáez-Nieto, J.A., Valdezate, S., Rodríguez-Pollán, H., Tauch, A., Soriano, F.: Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis. New Microbes and New Infections. 14, 93-97 (2016).
Fernández-Natal, I., Rodríguez-Lázaro, D., Marrodán-Ciordia, T., Sáez-Nieto, J.A., Valdezate, S., Rodríguez-Pollán, H., Tauch, Andreas, and Soriano, F. “Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis”. New Microbes and New Infections 14 (2016): 93-97.

1 Zitation in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Microbial Diversity in Milk of Women With Mastitis: Potential Role of Coagulase-Negative Staphylococci, Viridans Group Streptococci, and Corynebacteria.
Mediano P, Fernández L, Jiménez E, Arroyo R, Espinosa-Martos I, Rodríguez JM, Marín M., J Hum Lact 33(2), 2017
PMID: 28418794

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Quellen

PMID: 27818775
PubMed | Europe PMC

Suchen in

Google Scholar