Environmental Breviatea harbour mutualistic Arcobacter epibionts

Hamann E, Gruber-Vodicka H, Kleiner M, Tegetmeyer H, Riedel D, Littmann S, Chen J, Milucka J, Viehweger B, Becker KW, Dong X, et al. (2016)
NATURE 534(7606): 254-258.

Journal Article | Published | English

No fulltext has been uploaded

Author
; ; ; ; ; ; ; ; ; ; ;
All
Abstract
Breviatea form a lineage of free living, unicellular protists, distantly related to animals and fungi(1,2). This lineage emerged almost one billion years ago, when the oceanic oxygen content was low, and extant Breviatea have evolved or retained an anaerobic lifestyle(3,4). Here we report the cultivation of Lenisia limosa, gen. et sp. nov., a newly discovered breviate colonized by relatives of animal-associated Arcobacter. Physiological experiments show that the association of L. limosa with Arcobacter is driven by the transfer of hydrogen and is mutualistic, providing benefits to both partners. With whole-genome sequencing and differential proteomics, we show that an experimentally observed fitness gain of L. limosa could be explained by the activity of a so far unknown type of NAD(P) H-accepting hydrogenase, which is expressed in the presence, but not in the absence, of Arcobacter. Differential proteomics further reveal that the presence of Lenisia stimulates expression of known 'virulence' factors by Arcobacter. These proteins typically enable colonization of animal cells during infection(5), but may in the present case act for mutual benefit. Finally, re-investigation of two currently available transcriptomic data sets of other Breviatea(4) reveals the presence and activity of related hydrogen-consuming Arcobacter, indicating that mutualistic interaction between these two groups of microbes might be pervasive. Our results support the notion that molecular mechanisms involved in virulence can also support mutualism(6), as shown here for Arcobacter and Breviatea.
Publishing Year
ISSN
eISSN
PUB-ID

Cite this

Hamann E, Gruber-Vodicka H, Kleiner M, et al. Environmental Breviatea harbour mutualistic Arcobacter epibionts. NATURE. 2016;534(7606):254-258.
Hamann, E., Gruber-Vodicka, H., Kleiner, M., Tegetmeyer, H., Riedel, D., Littmann, S., Chen, J., et al. (2016). Environmental Breviatea harbour mutualistic Arcobacter epibionts. NATURE, 534(7606), 254-258.
Hamann, E., Gruber-Vodicka, H., Kleiner, M., Tegetmeyer, H., Riedel, D., Littmann, S., Chen, J., Milucka, J., Viehweger, B., Becker, K. W., et al. (2016). Environmental Breviatea harbour mutualistic Arcobacter epibionts. NATURE 534, 254-258.
Hamann, E., et al., 2016. Environmental Breviatea harbour mutualistic Arcobacter epibionts. NATURE, 534(7606), p 254-258.
E. Hamann, et al., “Environmental Breviatea harbour mutualistic Arcobacter epibionts”, NATURE, vol. 534, 2016, pp. 254-258.
Hamann, E., Gruber-Vodicka, H., Kleiner, M., Tegetmeyer, H., Riedel, D., Littmann, S., Chen, J., Milucka, J., Viehweger, B., Becker, K.W., Dong, X., Stairs, C.W., Hinrichs, K.-U., Brown, M.W., Roger, A.J., Strous, M.: Environmental Breviatea harbour mutualistic Arcobacter epibionts. NATURE. 534, 254-258 (2016).
Hamann, Emmo, Gruber-Vodicka, Harald, Kleiner, Manuel, Tegetmeyer, Halina, Riedel, Dietmar, Littmann, Sten, Chen, Jianwei, Milucka, Jana, Viehweger, Bernhard, Becker, Kevin W., Dong, Xiaoli, Stairs, Courtney W., Hinrichs, Kai-Uwe, Brown, Matthew W., Roger, Andrew J., and Strous, Marc. “Environmental Breviatea harbour mutualistic Arcobacter epibionts”. NATURE 534.7606 (2016): 254-258.
This data publication is cited in the following publications:
This publication cites the following data publications:

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 27279223
PubMed | Europe PMC

Search this title in

Google Scholar