Algal Photobiology: A Rich Source of Unusual Light Sensitive Proteins for Synthetic Biology and Optogenetics

Kianianmomeni A, Hallmann A (2016)
Methods Mol Biol 1408: 37-54.

Journal Article | English

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Abstract
The light absorption system in eukaryotic (micro)algae includes highly sensitive photoreceptors, which change their conformation in response to different light qualities on a subsecond time scale and induce physiological and behavioral responses. Some of the light sensitive modules are already in use to engineer and design photoswitchable tools for control of cellular and physiological activities in living organisms with various degrees of complexity. Thus, identification of new light sensitive modules will not only extend the source material for the generation of optogenetic tools but also foster the development of new light-based strategies in cell signaling research. Apart from searching for new proteins with suitable light-sensitive modules, smaller variants of existing light-sensitive modules would be helpful to simplify the construction of hybrid genes and facilitate the generation of mutated and chimerized modules. Advances in genome and transcriptome sequencing as well as functional analysis of photoreceptors and their interaction partners will help to discover new light sensitive modules.
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Financial disclosure
Article Processing Charge funded by the Deutsche Forschungsgemeinschaft and the Open Access Publication Fund of Bielefeld University.
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Kianianmomeni A, Hallmann A. Algal Photobiology: A Rich Source of Unusual Light Sensitive Proteins for Synthetic Biology and Optogenetics. Methods Mol Biol. 2016;1408:37-54.
Kianianmomeni, A., & Hallmann, A. (2016). Algal Photobiology: A Rich Source of Unusual Light Sensitive Proteins for Synthetic Biology and Optogenetics. Methods Mol Biol, 1408, 37-54.
Kianianmomeni, A., and Hallmann, A. (2016). Algal Photobiology: A Rich Source of Unusual Light Sensitive Proteins for Synthetic Biology and Optogenetics. Methods Mol Biol 1408, 37-54.
Kianianmomeni, A., & Hallmann, A., 2016. Algal Photobiology: A Rich Source of Unusual Light Sensitive Proteins for Synthetic Biology and Optogenetics. Methods Mol Biol, 1408, p 37-54.
A. Kianianmomeni and A. Hallmann, “Algal Photobiology: A Rich Source of Unusual Light Sensitive Proteins for Synthetic Biology and Optogenetics”, Methods Mol Biol, vol. 1408, 2016, pp. 37-54.
Kianianmomeni, A., Hallmann, A.: Algal Photobiology: A Rich Source of Unusual Light Sensitive Proteins for Synthetic Biology and Optogenetics. Methods Mol Biol. 1408, 37-54 (2016).
Kianianmomeni, Arash, and Hallmann, Armin. “Algal Photobiology: A Rich Source of Unusual Light Sensitive Proteins for Synthetic Biology and Optogenetics”. Methods Mol Biol 1408 (2016): 37-54.
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