The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nucleotide polymorphisms

Rupp O, Brinkrolf K, Buerth C, Kunigo M, Schneider J, Jaenicke S, Goesmann A, Pühler A, Jaeger K-E, Ernst JF (2015)
Journal of Biotechnology 211: 20-30.

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Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Abstract / Bemerkung
The yeast Cyberlindnera jadinii is a close relative of Candida utilis that is being used in the food and feed industries. Here, we present the 12.7Mb genome sequence of C. jadinii strain CBS 1600 generated by next generation sequencing. The deduced draft genome sequence consists of seven large scaffolds analogous to the seven largest chromosomes of C. utilis. An automated annotation of the C jadinii genome identified 6147 protein-coding sequences. The level of ploidy for both genomes was analyzed by calling single nucleotide polymorphisms (SNPs) and was verified measuring nuclear DNA contents by florescence activated cell sorting (FACS). Both analyses determined the level of ploidy to diploid for C. jadinii and to triploid for C utilis. However, SNP calling for C. jadinii also identified scaffold regions that seem to be haploid, triploid or tetraploid. (C) 2015 Elsevier B.V. All rights reserved.
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Zeitschriftentitel
Journal of Biotechnology
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211
Seite
20-30
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Rupp O, Brinkrolf K, Buerth C, et al. The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nucleotide polymorphisms. Journal of Biotechnology. 2015;211:20-30.
Rupp, O., Brinkrolf, K., Buerth, C., Kunigo, M., Schneider, J., Jaenicke, S., Goesmann, A., et al. (2015). The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nucleotide polymorphisms. Journal of Biotechnology, 211, 20-30. doi:10.1016/j.jbiotec.2015.06.423
Rupp, O., Brinkrolf, K., Buerth, C., Kunigo, M., Schneider, J., Jaenicke, S., Goesmann, A., Pühler, A., Jaeger, K. - E., and Ernst, J. F. (2015). The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nucleotide polymorphisms. Journal of Biotechnology 211, 20-30.
Rupp, O., et al., 2015. The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nucleotide polymorphisms. Journal of Biotechnology, 211, p 20-30.
O. Rupp, et al., “The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nucleotide polymorphisms”, Journal of Biotechnology, vol. 211, 2015, pp. 20-30.
Rupp, O., Brinkrolf, K., Buerth, C., Kunigo, M., Schneider, J., Jaenicke, S., Goesmann, A., Pühler, A., Jaeger, K.-E., Ernst, J.F.: The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nucleotide polymorphisms. Journal of Biotechnology. 211, 20-30 (2015).
Rupp, Oliver, Brinkrolf, Karina, Buerth, Christoph, Kunigo, Maya, Schneider, Jessica, Jaenicke, Sebastian, Goesmann, Alexander, Pühler, Alfred, Jaeger, Karl-Erich, and Ernst, Joachim F. “The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nucleotide polymorphisms”. Journal of Biotechnology 211 (2015): 20-30.

2 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Oral Tolerance Induction in Experimental Autoimmune Encephalomyelitis with Candida utilis Expressing the Immunogenic MOG35-55 Peptide.
Buerth C, Mausberg AK, Heininger MK, Hartung HP, Kieseier BC, Ernst JF., PLoS One 11(5), 2016
PMID: 27159446
Candida utilis and Cyberlindnera (Pichia) jadinii: yeast relatives with expanding applications.
Buerth C, Tielker D, Ernst JF., Appl Microbiol Biotechnol 100(16), 2016
PMID: 27357226

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