Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies

Huber B, Whibley A, Poul YL, Navarro N, Martin A, Baxter S, Shah A, Gilles B, Wirth T, McMillan WO, Joron M (2015)
Heredity 114(5): 515-524.

Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Autor
; ; ; ; ; ; ; ; ; ;
Abstract / Bemerkung
Understanding the genetic architecture of adaptive traits has been at the centre of modern evolutionary biology since Fisher; however, evaluating how the genetic architecture of ecologically important traits influences their diversification has been hampered by the scarcity of empirical data. Now, high-throughput genomics facilitates the detailed exploration of variation in the genome-to-phenotype map among closely related taxa. Here, we investigate the evolution of wing pattern diversity in Heliconius, a clade of neotropical butterflies that have undergone an adaptive radiation for wing-pattern mimicry and are influenced by distinct selection regimes. Using crosses between natural wing-pattern variants, we used genome-wide restriction site-associated DNA (RAD) genotyping, traditional linkage mapping and multivariate image analysis to study the evolution of the architecture of adaptive variation in two closely related species: Heliconius hecale and H. ismenius. We implemented a new morphometric procedure for the analysis of whole-wing pattern variation, which allows visualising spatial heatmaps of genotype-to-phenotype association for each quantitative trait locus separately. We used the H. melpomene reference genome to fine-map variation for each major wing-patterning region uncovered, evaluated the role of candidate genes and compared genetic architectures across the genus. Our results show that, although the loci responding to mimicry selection are highly conserved between species, their effect size and phenotypic action vary throughout the clade. Multilocus architecture is ancestral and maintained across species under directional selection, whereas the single-locus (supergene) inheritance controlling polymorphism in H. numata appears to have evolved only once. Nevertheless, the conservatism in the wing-patterning toolkit found throughout the genus does not appear to constrain phenotypic evolution towards local adaptive optima.
Erscheinungsjahr
Zeitschriftentitel
Heredity
Band
114
Zeitschriftennummer
5
Seite
515-524
ISSN
PUB-ID

Zitieren

Huber B, Whibley A, Poul YL, et al. Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies. Heredity. 2015;114(5):515-524.
Huber, B., Whibley, A., Poul, Y. L., Navarro, N., Martin, A., Baxter, S., Shah, A., et al. (2015). Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies. Heredity, 114(5), 515-524. doi:10.1038/hdy.2015.22
Huber, B., Whibley, A., Poul, Y. L., Navarro, N., Martin, A., Baxter, S., Shah, A., Gilles, B., Wirth, T., McMillan, W. O., et al. (2015). Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies. Heredity 114, 515-524.
Huber, B., et al., 2015. Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies. Heredity, 114(5), p 515-524.
B. Huber, et al., “Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies”, Heredity, vol. 114, 2015, pp. 515-524.
Huber, B., Whibley, A., Poul, Y.L., Navarro, N., Martin, A., Baxter, S., Shah, A., Gilles, B., Wirth, T., McMillan, W.O., Joron, M.: Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies. Heredity. 114, 515-524 (2015).
Huber, B., Whibley, A., Poul, Y. L., Navarro, N., Martin, A., Baxter, S., Shah, Abhijeet, Gilles, B., Wirth, T., McMillan, W. O., and Joron, M. “Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies”. Heredity 114.5 (2015): 515-524.

11 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Complex modular architecture around a simple toolkit of wing pattern genes.
Van Belleghem SM, Rastas P, Papanicolaou A, Martin SH, Arias CF, Supple MA, Hanly JJ, Mallet J, Lewis JJ, Hines HM, Ruiz M, Salazar C, Linares M, Moreira GRP, Jiggins CD, Counterman BA, McMillan WO, Papa R., Nat Ecol Evol 1(3), 2017
PMID: 28523290
Waiting in the wings: what can we learn about gene co-option from the diversification of butterfly wing patterns?
Jiggins CD, Wallbank RW, Hanly JJ., Philos Trans R Soc Lond B Biol Sci 372(1713), 2017
PMID: 27994126
Polymorphism at a mimicry supergene maintained by opposing frequency-dependent selection pressures.
Chouteau M, Llaurens V, Piron-Prunier F, Joron M., Proc Natl Acad Sci U S A 114(31), 2017
PMID: 28673971
Macroevolutionary shifts of WntA function potentiate butterfly wing-pattern diversity.
Mazo-Vargas A, Concha C, Livraghi L, Massardo D, Wallbank RWR, Zhang L, Papador JD, Martinez-Najera D, Jiggins CD, Kronforst MR, Breuker CJ, Reed RD, Patel NH, McMillan WO, Martin A., Proc Natl Acad Sci U S A 114(40), 2017
PMID: 28923954
Crossing fitness valleys: empirical estimation of a fitness landscape associated with polymorphic mimicry.
Arias M, le Poul Y, Chouteau M, Boisseau R, Rosser N, Théry M, Llaurens V., Proc Biol Sci 283(1829), 2016
PMID: 27122560
The genetic basis of discrete and quantitative colour variation in the polymorphic lizard, Ctenophorus decresii.
Rankin KJ, McLean CA, Kemp DJ, Stuart-Fox D., BMC Evol Biol 16(), 2016
PMID: 27600682
The diversification of Heliconius butterflies: what have we learned in 150 years?
Merrill RM, Dasmahapatra KK, Davey JW, Dell'Aglio DD, Hanly JJ, Huber B, Jiggins CD, Joron M, Kozak KM, Llaurens V, Martin SH, Montgomery SH, Morris J, Nadeau NJ, Pinharanda AL, Rosser N, Thompson MJ, Vanjari S, Wallbank RW, Yu Q., J Evol Biol 28(8), 2015
PMID: 26079599
Replaying the tape of life in the twenty-first century.
Orgogozo V., Interface Focus 5(6), 2015
PMID: 26640652

57 References

Daten bereitgestellt von Europe PubMed Central.

Genomic architecture of adaptive color pattern divergence and convergence in Heliconius butterflies.
Supple MA, Hines HM, Dasmahapatra KK, Lewis JJ, Nielsen DM, Lavoie C, Ray DA, Salazar C, McMillan WO, Counterman BA., Genome Res. 23(8), 2013
PMID: 23674305
Supergenes and their role in evolution.
Thompson MJ, Jiggins CD., Heredity (Edinb) 113(1), 2014
PMID: 24642887

Turner, Evol Biol 10(), 1977
Absence of crossing-over in female butterflies (Heliconius).
Turner JR, Sheppard PM., Heredity (Edinb) 34 Part 2(), 1975
PMID: 1055712

AUTHOR UNKNOWN, 0

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 25806542
PubMed | Europe PMC

Suchen in

Google Scholar