Prevalence and risks of undiagnosed diabetes mellitus in patients undergoing coronary artery bypass grafting

Lauruschkat AH, Arnrich B, Albert AA, Walter JA, Amann B, Rosendahl UP, Alexander T, Ennker J (2005)
Circulation 112(16): 2397-2402.

Download
No fulltext has been uploaded. References only!
Journal Article | Published | English

No fulltext has been uploaded

Author
; ; ; ; ; ; ;
Abstract
Background— Numerous studies have shown that diabetes mellitus (DM) is not identified and, consequently, inadequately treated in a substantial proportion of the patients in the general population. We know very little about the extent and the consequences of undiagnosed diabetes in the risk group of patients with coronary heart diseases. The objective of this study was therefore to determine the prevalence and the risks of undiagnosed DM among patients with coronary artery bypass. Methods and Results— The data of 7310 patients who have undergone coronary bypass operations between 1996 and 2003 were analyzed. Depending on their diagnosis on admission and their fasting plasma glucose (FPG) level, these patients were classified as known diabetics, undiagnosed diabetics (FPG ≥126 mg/dL), or as nondiabetics (FPG <126 mg/dL) and were compared in terms of their preoperative, intraoperative, and postoperative characteristics. Among the patients with coronary bypass that we examined, we found a prevalence of diagnosed diabetics of 29.6%. The prevalence of patients with undiagnosed DM (FPG ≥126 mg/dL) was 5.2%. In comparison with the other groups (non-DM versus undiagnosed DM versus known DM), the undiagnosed diabetics more frequently required resuscitation (1.7% versus 4.2% versus 1.5%; P<0.01) and reintubation (2.1% versus 5.0% versus 3.5%; P<0.01) and often showed a longer period of ventilation >1 day (5.6% versus 10.5% versus 7.4%; P<0.01). Perioperative mortality rate was highest in this group (0.9% versus 2.4% versus 1.4%; P<0.01). Conclusions— This study is the first to publish the prevalence of undiagnosed diabetes mellitus in cardiac surgery. During the perioperative and postoperative courses, these patients displayed a substantially higher morbidity and mortality rate.
Publishing Year
PUB-ID

Cite this

Lauruschkat AH, Arnrich B, Albert AA, et al. Prevalence and risks of undiagnosed diabetes mellitus in patients undergoing coronary artery bypass grafting. Circulation. 2005;112(16):2397-2402.
Lauruschkat, A. H., Arnrich, B., Albert, A. A., Walter, J. A., Amann, B., Rosendahl, U. P., Alexander, T., et al. (2005). Prevalence and risks of undiagnosed diabetes mellitus in patients undergoing coronary artery bypass grafting. Circulation, 112(16), 2397-2402. doi:10.1161/CIRCULATIONAHA.105.534545
Lauruschkat, A. H., Arnrich, B., Albert, A. A., Walter, J. A., Amann, B., Rosendahl, U. P., Alexander, T., and Ennker, J. (2005). Prevalence and risks of undiagnosed diabetes mellitus in patients undergoing coronary artery bypass grafting. Circulation 112, 2397-2402.
Lauruschkat, A.H., et al., 2005. Prevalence and risks of undiagnosed diabetes mellitus in patients undergoing coronary artery bypass grafting. Circulation, 112(16), p 2397-2402.
A.H. Lauruschkat, et al., “Prevalence and risks of undiagnosed diabetes mellitus in patients undergoing coronary artery bypass grafting”, Circulation, vol. 112, 2005, pp. 2397-2402.
Lauruschkat, A.H., Arnrich, B., Albert, A.A., Walter, J.A., Amann, B., Rosendahl, U.P., Alexander, T., Ennker, J.: Prevalence and risks of undiagnosed diabetes mellitus in patients undergoing coronary artery bypass grafting. Circulation. 112, 2397-2402 (2005).
Lauruschkat, Achim H., Arnrich, Bert, Albert, Alexander A., Walter, Jörg A., Amann, Berthold, Rosendahl, Ulrich P., Alexander, Tejas, and Ennker, Jürgen. “Prevalence and risks of undiagnosed diabetes mellitus in patients undergoing coronary artery bypass grafting”. Circulation 112.16 (2005): 2397-2402.
This data publication is cited in the following publications:
This publication cites the following data publications:

41 Citations in Europe PMC

Data provided by Europe PubMed Central.

Effect of glycaemic control on complications following cardiac surgery: literature review.
Navaratnarajah M, Rea R, Evans R, Gibson F, Antoniades C, Keiralla A, Demosthenous M, Kassimis G, Krasopoulos G., J Cardiothorac Surg 13(1), 2018
PMID: 29343294
[Evaluation and perioperative management of patients with diabetes mellitus. A challenge for the anesthesiologist].
Pontes JPJ, Mendes FF, Vasconcelos MM, Batista NR., Rev Bras Anestesiol 68(1), 2018
PMID: 28571661
Management of Hyperglycemia and Diabetes in Orthopedic Surgery.
Akiboye F, Rayman G., Curr. Diab. Rep. 17(2), 2017
PMID: 28265893
Meta-Analysis on the Association of ALDH2 Polymorphisms and Type 2 Diabetic Mellitus, Diabetic Retinopathy.
Li GY, Li ZB, Li F, Dong LP, Tang L, Xiang J, Li JM, Bao MH., Int J Environ Res Public Health 14(2), 2017
PMID: 28208752
Severity of coronary artery disease and retinal microvascular signs in patients with diagnosed versus undiagnosed diabetes: cross-sectional study.
Phan K, Mitchell P, Liew G, Plant AJ, Wang SB, Xu J, Chiha J, Thiagalingam A, Burlutsky G, Gopinath B., J Thorac Dis 8(7), 2016
PMID: 27499940
Awareness, treatment and control of cardiometabolic disorders in Chinese adults with diabetes: a national representative population study.
Wang T, Xu Y, Xu M, Wang W, Bi Y, Lu J, Dai M, Zhang D, Ding L, Xu B, Sun J, Zhao W, Jiang Y, Wang L, Li Y, Zhang M, Lai S, Wang L, Ning G., Cardiovasc Diabetol 14(), 2015
PMID: 25848699
Preparation for percutaneous ablation procedures.
Brennan IM, Faintuch S, Ahmed M., Tech Vasc Interv Radiol 16(4), 2013
PMID: 24238376
High incidence of insulin resistance and dysglycemia amongst nondiabetic cardiac surgical patients.
Hofferberth SC, Newcomb AE, Ryan MC, Yii MY, Nixon IK, Rosalion A, Boston RC, Ward GM, Wilson AM., Ann. Thorac. Surg. 94(1), 2012
PMID: 22503851
Perioperative mortality in diabetic patients undergoing coronary artery bypass graft surgery.
Sa MP, Soares EF, Santos CA, Figueiredo OJ, Lima RO, Escobar RR, Rueda FG, Lima Rde C., Rev Col Bras Cir 39(1), 2012
PMID: 22481702
[Perioperative management of long-term medication].
Vogel Kahmann I, Ruppen W, Lurati Buse G, Tsakiris DA, Bruggisser M., Internist (Berl) 52(1), 2011
PMID: 21088954
Evidence-based guidelines for perioperative management of diabetes in cardiac and vascular surgery.
Wong J, Zoungas S, Wright C, Teede H., World J Surg 34(3), 2010
PMID: 20076958
Preoperative evaluation and preparation of the patient for cardiac surgery.
Weisberg AD, Weisberg EL, Wilson JM, Collard CD., Anesthesiol Clin 27(4), 2009
PMID: 19942171
Optimizing perioperative glycemic control.
Sharma S, Canos M, Falciglia M., Int Anesthesiol Clin 47(4), 2009
PMID: 19820481
Preoperative evaluation and preparation of the patient for cardiac surgery.
Weisberg AD, Weisberg EL, Wilson JM, Collard CD., Med. Clin. North Am. 93(5), 2009
PMID: 19665615

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 16230496
PubMed | Europe PMC

Search this title in

Google Scholar