Squeezing red blood cells on an optical waveguide to monitor cell deformability during blood storage

Ahluwalia BS, McCourt P, Oteiza A, Wilkinson JS, Huser T, Helleso OG (2015)
Analyst 140(1): 223-229.

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Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Abstract / Bemerkung
Red blood cells squeeze through micro-capillaries as part of blood circulation in the body. The deformability of red blood cells is thus critical for blood circulation. In this work, we report a method to optically squeeze red blood cells using the evanescent field present on top of a planar waveguide chip. The optical forces from a narrow waveguide are used to squeeze red blood cells to a size comparable to the waveguide width. Optical forces and pressure distributions on the cells are numerically computed to explain the squeezing process. The proposed technique is used to quantify the loss of blood deformability that occurs during blood storage lesion. Squeezing red blood cells using waveguides is a sensitive technique and works simultaneously on several cells, making the method suitable for monitoring stored blood.
Erscheinungsjahr
Zeitschriftentitel
Analyst
Band
140
Zeitschriftennummer
1
Seite
223-229
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Ahluwalia BS, McCourt P, Oteiza A, Wilkinson JS, Huser T, Helleso OG. Squeezing red blood cells on an optical waveguide to monitor cell deformability during blood storage. Analyst. 2015;140(1):223-229.
Ahluwalia, B. S., McCourt, P., Oteiza, A., Wilkinson, J. S., Huser, T., & Helleso, O. G. (2015). Squeezing red blood cells on an optical waveguide to monitor cell deformability during blood storage. Analyst, 140(1), 223-229. doi:10.1039/c4an01181c
Ahluwalia, B. S., McCourt, P., Oteiza, A., Wilkinson, J. S., Huser, T., and Helleso, O. G. (2015). Squeezing red blood cells on an optical waveguide to monitor cell deformability during blood storage. Analyst 140, 223-229.
Ahluwalia, B.S., et al., 2015. Squeezing red blood cells on an optical waveguide to monitor cell deformability during blood storage. Analyst, 140(1), p 223-229.
B.S. Ahluwalia, et al., “Squeezing red blood cells on an optical waveguide to monitor cell deformability during blood storage”, Analyst, vol. 140, 2015, pp. 223-229.
Ahluwalia, B.S., McCourt, P., Oteiza, A., Wilkinson, J.S., Huser, T., Helleso, O.G.: Squeezing red blood cells on an optical waveguide to monitor cell deformability during blood storage. Analyst. 140, 223-229 (2015).
Ahluwalia, Balpreet Singh, McCourt, Peter, Oteiza, Ana, Wilkinson, James S., Huser, Thomas, and Helleso, Olav Gaute. “Squeezing red blood cells on an optical waveguide to monitor cell deformability during blood storage”. Analyst 140.1 (2015): 223-229.

2 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Nanophotonic trapping: precise manipulation and measurement of biomolecular arrays.
Baker JE, Badman RP, Wang MD., Wiley Interdiscip Rev Nanomed Nanobiotechnol 10(1), 2018
PMID: 28439980

38 References

Daten bereitgestellt von Europe PubMed Central.


Brevik, Phys. Rep. 52(), 1979

Brevik, J. Opt. Soc. Am. B 16(), 1999
Viscoelastic and biochemical properties of erythrocytes during storage with SAG-M at +4 degrees C.
Farges E, Grebe R, Baumann M., Clin. Hemorheol. Microcirc. 27(1), 2002
PMID: 12237485
Evolution of adverse changes in stored RBCs.
Bennett-Guerrero E, Veldman TH, Doctor A, Telen MJ, Ortel TL, Reid TS, Mulherin MA, Zhu H, Buck RD, Califf RM, McMahon TJ., Proc. Natl. Acad. Sci. U.S.A. 104(43), 2007
PMID: 17940021

Fontes, J. Opt. 13(), 2011

Cluitmans, Blood Transfusion 10(), 2012
Survival of red blood cells after transfusion: a comparison between red cells concentrates of different storage periods.
Luten M, Roerdinkholder-Stoelwinder B, Schaap NP, de Grip WJ, Bos HJ, Bosman GJ., Transfusion 48(7), 2008
PMID: 18482180
Laser-assisted optical rotational cell analyzer measurements reveal early changes in human RBC deformability induced by photodynamic treatment.
Hardeman MR, Besselink GA, Ebbing I, de Korte D, Ince C, Verhoeven AJ., Transfusion 43(11), 2003
PMID: 14617311

Lecklin, Pfluegers Arch. 432(), 1996
Proteomic analysis of RBC membrane protein degradation during blood storage.
D'Amici GM, Rinalducci S, Zolla L., J. Proteome Res. 6(8), 2007
PMID: 17585793
Refractive index maps and membrane dynamics of human red blood cells parasitized by Plasmodium falciparum.
Park Y, Diez-Silva M, Popescu G, Lykotrafitis G, Choi W, Feld MS, Suresh S., Proc. Natl. Acad. Sci. U.S.A. 105(37), 2008
PMID: 18772382

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