A new xanthone derivative from twigs of Garcinia nobilis

Fouotsa H, Tatsimo SJN, Neumann B, Michalek C, Mbazoa CD, Nkengfack AE, Sewald N, Lannang AM (2014)
Natural Product Research 28(14): 1030-1036.

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Abstract
Phytochemical investigation of the twigs of Garcinia nobilis led to the isolation of a new xanthone, named l-hydroxy-2,5-dimethoxyxanthone (1), together with 15 known compounds (2-16). The structures of the new and known compounds were established by means of spectroscopic methods and by comparison with previously reported data. The structure of compound 1 was confirmed by X-ray diffraction data. Compounds 1-16 were tested for their cytotoxic activity against human cervix carcinoma cell line KB-3-1. Compounds 5 and 11 showed moderate activity while others showed weak biological activity in these cytotoxicity assays. Compounds 4 and 9 were found to be inactive.
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Fouotsa H, Tatsimo SJN, Neumann B, et al. A new xanthone derivative from twigs of Garcinia nobilis. Natural Product Research. 2014;28(14):1030-1036.
Fouotsa, H., Tatsimo, S. J. N., Neumann, B., Michalek, C., Mbazoa, C. D., Nkengfack, A. E., Sewald, N., et al. (2014). A new xanthone derivative from twigs of Garcinia nobilis. Natural Product Research, 28(14), 1030-1036.
Fouotsa, H., Tatsimo, S. J. N., Neumann, B., Michalek, C., Mbazoa, C. D., Nkengfack, A. E., Sewald, N., and Lannang, A. M. (2014). A new xanthone derivative from twigs of Garcinia nobilis. Natural Product Research 28, 1030-1036.
Fouotsa, H., et al., 2014. A new xanthone derivative from twigs of Garcinia nobilis. Natural Product Research, 28(14), p 1030-1036.
H. Fouotsa, et al., “A new xanthone derivative from twigs of Garcinia nobilis”, Natural Product Research, vol. 28, 2014, pp. 1030-1036.
Fouotsa, H., Tatsimo, S.J.N., Neumann, B., Michalek, C., Mbazoa, C.D., Nkengfack, A.E., Sewald, N., Lannang, A.M.: A new xanthone derivative from twigs of Garcinia nobilis. Natural Product Research. 28, 1030-1036 (2014).
Fouotsa, Hugues, Tatsimo, Simplice J. N., Neumann, Beate, Michalek, Carmela, Mbazoa, Celine Djama, Nkengfack, Augustin Ephrem, Sewald, Norbert, and Lannang, Alain Meli. “A new xanthone derivative from twigs of Garcinia nobilis”. Natural Product Research 28.14 (2014): 1030-1036.
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25 References

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AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0

AUTHOR UNKNOWN, 0
Antimalarial xanthones from Calophyllum caledonicum and Garcinia vieillardii.
Hay AE, Helesbeux JJ, Duval O, Labaied M, Grellier P, Richomme P., Life Sci. 75(25), 2004
PMID: 15474559

AUTHOR UNKNOWN, 0
Xanthones from Garcinia smeathmannii (Oliver) and their antimicrobial activity.
Komguem J, Meli AL, Manfouo RN, Lontsi D, Ngounou FN, Kuete V, Kamdem HW, Tane P, Ngadjui BT, Sondengam BL, Connolly JD., Phytochemistry 66(14), 2005
PMID: 15907961

Kuete, Pharmacology Online 3(), 2007

Li, J Chin Pharm Sci (), 2012
Xanthones from the roots of Cudrania fruticosa Wight.
Liang B, Li HR, Xu LZ, Yang SL., J Asian Nat Prod Res 9(3-5), 2007
PMID: 17613626

Locksley, J Chem Soc (), 1971
Xanthones and triterpenoids from the bark of Garcinia vilersiana.
Nguyen LH, Harrison LJ., Phytochemistry 53(1), 2000
PMID: 10656417
A sugar ester and an iridoid glycoside from Scrophularia ningpoensis.
Nguyen AT, Fontaine J, Malonne H, Claeys M, Luhmer M, Duez P., Phytochemistry 66(10), 2005
PMID: 15924924
Isolation and bioactivities of constitutents of the roots of Garcinia atroviridis.
Permana D, Lajis NH, Mackeen MM, Ali AM, Aimi N, Kitajima M, Takayama H., J. Nat. Prod. 64(7), 2001
PMID: 11473441

AUTHOR UNKNOWN, 0
Approaches for the synthesis of functionalized cryptophycins.
Sammet B, Bogner T, Nahrwold M, Weiss C, Sewald N., J. Org. Chem. 75(20), 2010
PMID: 20857920
Cytotoxic caged-polyprenylated xanthonoids and a xanthone from Garcinia cantleyana.
Shadid KA, Shaari K, Abas F, Israf DA, Hamzah AS, Syakroni N, Saha K, Lajis NH., Phytochemistry 68(20), 2007
PMID: 17602714

AUTHOR UNKNOWN, 0
Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana.
Suksamrarn S, Suwannapoch N, Phakhodee W, Thanuhiranlert J, Ratananukul P, Chimnoi N, Suksamrarn A., Chem. Pharm. Bull. 51(7), 2003
PMID: 12843596
Xanthones from Polygala karensium inhibit neuraminidases from influenza A viruses.
Dao TT, Dang TT, Nguyen PH, Kim E, Thuong PT, Oh WK., Bioorg. Med. Chem. Lett. 22(11), 2012
PMID: 22552195

AUTHOR UNKNOWN, 0
Phloroglucinols with prooxidant activity from Garcinia subelliptica.
Wu CC, Lu YH, Wei BL, Yang SC, Won SJ, Lin CN., J. Nat. Prod. 71(2), 2008
PMID: 18166016
Immunomodulatory and anticancer activities of phenolics from Garcinia mangostana fruit pericarp
Yu Limei, Zhao Mouming, Yang Bao, Bai Weidong., Food Chem 116(4), 2009
PMID: IND44214284

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