Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum

Kulis-Horn R, Persicke M, Kalinowski J (2014)
Microbial Biotechnology 7(1): 5-25.

Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Abstract / Bemerkung
l-Histidine biosynthesis is an ancient metabolic pathway present in bacteria, archaea, lower eukaryotes, and plants. For decades l-histidine biosynthesis has been studied mainly in Escherichia coli and Salmonella typhimurium, revealing fundamental regulatory processes in bacteria. Furthermore, in the last 15 years this pathway has been also investigated intensively in the industrial amino acid-producing bacterium Corynebacterium glutamicum, revealing similarities to E.coli and S.typhimurium, as well as differences. This review summarizes the current knowledge of l-histidine biosynthesis in C.glutamicum. The genes involved and corresponding enzymes are described, in particular focusing on the imidazoleglycerol-phosphate synthase (HisFH) and the histidinol-phosphate phosphatase (HisN). The transcriptional organization of his genes in C.glutamicum is also reported, including the four histidine operons and their promoters. Knowledge of transcriptional regulation during stringent response and by histidine itself is summarized and a translational regulation mechanism is discussed, as well as clues about a histidine transport system. Finally, we discuss the potential of using this knowledge to create or improve C.glutamicum strains for the industrial l-histidine production.
Erscheinungsjahr
Zeitschriftentitel
Microbial Biotechnology
Band
7
Zeitschriftennummer
1
Seite
5-25
ISSN
PUB-ID

Zitieren

Kulis-Horn R, Persicke M, Kalinowski J. Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum. Microbial Biotechnology. 2014;7(1):5-25.
Kulis-Horn, R., Persicke, M., & Kalinowski, J. (2014). Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum. Microbial Biotechnology, 7(1), 5-25. doi:10.1111/1751-7915.12055
Kulis-Horn, R., Persicke, M., and Kalinowski, J. (2014). Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum. Microbial Biotechnology 7, 5-25.
Kulis-Horn, R., Persicke, M., & Kalinowski, J., 2014. Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum. Microbial Biotechnology, 7(1), p 5-25.
R. Kulis-Horn, M. Persicke, and J. Kalinowski, “Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum”, Microbial Biotechnology, vol. 7, 2014, pp. 5-25.
Kulis-Horn, R., Persicke, M., Kalinowski, J.: Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum. Microbial Biotechnology. 7, 5-25 (2014).
Kulis-Horn, Robert, Persicke, Marcus, and Kalinowski, Jörn. “Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum”. Microbial Biotechnology 7.1 (2014): 5-25.

15 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Determination of the small RNA GcvB regulon in the Gram-negative bacterial pathogen Pasteurella multocida and identification of the GcvB seed binding region.
Gulliver EL, Wright A, Lucas DD, Mégroz M, Kleifeld O, Schittenhelm RB, Powell DR, Seemann T, Bulitta JB, Harper M, Boyce JD., RNA 24(5), 2018
PMID: 29440476
Insights Into the Roles of Two Genes of the Histidine Biosynthesis Operon in Pathogenicity of Xanthomonas oryzae pv. oryzicola.
Su P, Song Z, Wu G, Zhao Y, Zhang Y, Wang B, Qian G, Fu ZQ, Liu F., Phytopathology 108(5), 2018
PMID: 29256829
Histidine Metabolism and IGPD Play a Key Role in Cefquinome Inhibiting Biofilm Formation of Staphylococcus xylosus.
Zhou YH, Xu CG, Yang YB, Xing XX, Liu X, Qu QW, Ding WY, Bello-Onaghise G, Li YH., Front Microbiol 9(), 2018
PMID: 29675012
The RamA regulon: complex regulatory interactions in relation to central metabolism in Corynebacterium glutamicum.
Shah A, Blombach B, Gauttam R, Eikmanns BJ., Appl Microbiol Biotechnol 102(14), 2018
PMID: 29804137
Allosteric Activation Shifts the Rate-Limiting Step in a Short-Form ATP Phosphoribosyltransferase.
Fisher G, Thomson CM, Stroek R, Czekster CM, Hirschi JS, da Silva RG., Biochemistry 57(29), 2018
PMID: 29940105
HisB as novel selection marker for gene targeting approaches in Aspergillus niger.
Fiedler MR, Gensheimer T, Kubisch C, Meyer V., BMC Microbiol 17(1), 2017
PMID: 28274204
Genome improvement of the acarbose producer Actinoplanes sp. SE50/110 and annotation refinement based on RNA-seq analysis.
Wolf T, Schneiker-Bekel S, Neshat A, Ortseifen V, Wibberg D, Zemke T, Pühler A, Kalinowski J., J Biotechnol 251(), 2017
PMID: 28427920
Independent catalysis of the short form HisG from Lactococcus lactis.
Livingstone EK, Mittelstädt G, Given FM, Parker EJ., FEBS Lett 590(16), 2016
PMID: 27393206
Characterization and molecular mechanism of AroP as an aromatic amino acid and histidine transporter in Corynebacterium glutamicum.
Shang X, Zhang Y, Zhang G, Chai X, Deng A, Liang Y, Wen T., J Bacteriol 195(23), 2013
PMID: 24056108
Comprehensive analysis of the Corynebacterium glutamicum transcriptome using an improved RNAseq technique.
Pfeifer-Sancar K, Mentz A, Rückert C, Kalinowski J., BMC Genomics 14(), 2013
PMID: 24341750

121 References

Daten bereitgestellt von Europe PubMed Central.

The enzymatic synthesis of histidine from histidinol.
ADAMS E., J. Biol. Chem. 209(2), 1954
PMID: 13192138
Arabinan-deficient mutants of Corynebacterium glutamicum and the consequent flux in decaprenylmonophosphoryl-D-arabinose metabolism.
Alderwick LJ, Dover LG, Seidel M, Gande R, Sahm H, Eggeling L, Besra GS., Glycobiology 16(11), 2006
PMID: 16891347
Processing of a polycistronic mRNA requires a 5' cis element and active translation.
Alifano P, Piscitelli C, Blasi V, Rivellini F, Nappo AG, Bruni CB, Carlomagno MS., Mol. Microbiol. 6(6), 1992
PMID: 1374148
Histidine biosynthetic pathway and genes: structure, regulation, and evolution.
Alifano P, Fani R, Lio P, Lazcano A, Bazzicalupo M, Carlomagno MS, Bruni CB., Microbiol. Rev. 60(1), 1996
PMID: 8852895
Structural elements in IGP synthase exclude water to optimize ammonia transfer.
Amaro RE, Myers RS, Davisson VJ, Luthey-Schulten ZA., Biophys. J. 89(1), 2005
PMID: 15849257
Histidine and aromatic permeases of Salmonella typhimurim.
Ames GF, Roth JR., J. Bacteriol. 96(5), 1968
PMID: 4882022
Studies on histidine fermentation: Part I. l-histidine production by histidine analog-resistant mutants from several bacteria
Araki K, Nakayama K., 1971
Feedback-resistant phosphoribosyl-ATP pyrophosphorylase in l-histidine-producing mutants of Corynebacterium glutamicum
Araki K, Nakayama K., 1974
Cloning and characterization of a bifunctional RelA/SpoT homologue from Mycobacterium tuberculosis.
Avarbock D, Salem J, Li LS, Wang ZM, Rubin H., Gene 233(1-2), 1999
PMID: 10375643
Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Barbosa JA, Sivaraman J, Li Y, Larocque R, Matte A, Schrag JD, Cygler M., Proc. Natl. Acad. Sci. U.S.A. 99(4), 2002
PMID: 11842181
Systems and synthetic metabolic engineering for amino acid production – the heartbeat of industrial strain development
Becker J, Wittmann C., 2011
From zero to hero--design-based systems metabolic engineering of Corynebacterium glutamicum for L-lysine production.
Becker J, Zelder O, Hafner S, Schroder H, Wittmann C., Metab. Eng. 13(2), 2011
PMID: 21241816
Expression control and specificity of the basic amino acid exporter LysE of Corynebacterium glutamicum.
Bellmann A, Vrljic M, Patek M, Sahm H, Kramer R, Eggeling L., Microbiology (Reading, Engl.) 147(Pt 7), 2001
PMID: 11429454
Corynebacterium glutamicum tailored for efficient isobutanol production.
Blombach B, Riester T, Wieschalka S, Ziert C, Youn JW, Wendisch VF, Eikmanns BJ., Appl. Environ. Microbiol. 77(10), 2011
PMID: 21441331
Proteobacterial histidine-biosynthetic pathways are paraphyletic.
Bond JP, Francklyn C., J. Mol. Evol. 50(4), 2000
PMID: 10795825
The histidine operon and its regulation
Brenner M, Ames BN., 1971
Molecular evolution of hisB genes.
Brilli M, Fani R., J. Mol. Evol. 58(2), 2004
PMID: 15042344
Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv.
Camus JC, Pryor MJ, Medigue C, Cole ST., Microbiology (Reading, Engl.) 148(Pt 10), 2002
PMID: 12368430
Structure and function of the Salmonella typhimurium and Escherichia coli K-12 histidine operons.
Carlomagno MS, Chiariotti L, Alifano P, Nappo AG, Bruni CB., J. Mol. Biol. 203(3), 1988
PMID: 3062174
Regulation of bacterial ppGpp and pppGpp.
Cashel M., Annu. Rev. Microbiol. 29(), 1975
PMID: 170852
Gene-enzyme relationships in histidine biosynthesis in Bacillus subtilis.
Chapman LF, Nester EW., J. Bacteriol. 97(3), 1969
PMID: 4975750
Revisiting the stringent response, ppGpp and starvation signaling.
Chatterji D, Ojha AK., Curr. Opin. Microbiol. 4(2), 2001
PMID: 11282471
Crystal structure of ATP phosphoribosyltransferase from Mycobacterium tuberculosis.
Cho Y, Sharma V, Sacchettini JC., J. Biol. Chem. 278(10), 2003
PMID: 12511575
Bisubstrate specificity in histidine/tryptophan biosynthesis isomerase from Mycobacterium tuberculosis by active site metamorphosis.
Due AV, Kuper J, Geerlof A, von Kries JP, Wilmanns M., Proc. Natl. Acad. Sci. U.S.A. 108(9), 2011
PMID: 21321225

AUTHOR UNKNOWN, 2005
Lysine secretion by wild-type Corynebacterium glutamicum triggered by dipeptide uptake
Erdmann A, Weil B, Krämer R., 1993
The role of gene fusions in the evolution of metabolic pathways: the histidine biosynthesis case.
Fani R, Brilli M, Fondi M, Lio P., BMC Evol. Biol. 7 Suppl 2(), 2007
PMID: 17767732

Goodfellow M, Kämpfer P, Busse H-J, Trujillo ME, Suzuki K-I, Ludwig W, Whitman WB., 2012
Binding of histidinal to histidinol dehydrogenase.
Gorisch H, Holke W., Eur. J. Biochem. 150(2), 1985
PMID: 3894023
L-histidinol dehydrogenase, a Zn2+-metalloenzyme.
Grubmeyer C, Skiadopoulos M, Senior AE., Arch. Biochem. Biophys. 272(2), 1989
PMID: 2665648
Biochemical features and functional implications of the RNA-based T-box regulatory mechanism.
Gutierrez-Preciado A, Henkin TM, Grundy FJ, Yanofsky C, Merino E., Microbiol. Mol. Biol. Rev. 73(1), 2009
PMID: 19258532
Fine structure mapping by complete transduction between histidine-requiring Salmonella mutants.
HARTMAN PE, LOPER JC, SERMAN D., J. Gen. Microbiol. 22(), 1960
PMID: 14400144
Glutamate is excreted across the cytoplasmic membrane through the NCgl1221 channel of Corynebacterium glutamicum by passive diffusion.
Hashimoto K, Murata J, Konishi T, Yabe I, Nakamatsu T, Kawasaki H., Biosci. Biotechnol. Biochem. 76(7), 2012
PMID: 22785475
tRNA-directed transcription antitermination.
Henkin TM., Mol. Microbiol. 13(3), 1994
PMID: 7527891
Prokaryotic transcription regulators: more than just the helix-turn-helix motif.
Huffman JL, Brennan RG., Curr. Opin. Struct. Biol. 12(1), 2002
PMID: 11839496
Amino acid production processes.
Ikeda M., Adv. Biochem. Eng. Biotechnol. 79(), 2003
PMID: 12523387
The Corynebacterium glutamicum genome: features and impacts on biotechnological processes.
Ikeda M, Nakagawa S., Appl. Microbiol. Biotechnol. 62(2-3), 2003
PMID: 12743753
ppGpp: stringent response and survival.
Jain V, Kumar M, Chatterji D., J. Microbiol. 44(1), 2006
PMID: 16554711
The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis.
Javid-Majd F, Yang D, Ioerger TR, Sacchettini JC., Acta Crystallogr. D Biol. Crystallogr. 64(Pt 6), 2008
PMID: 18560150
Model for regulation of the histidine operon of Salmonella.
Johnston HM, Barnes WM, Chumley FG, Bossi L, Roth JR., Proc. Natl. Acad. Sci. U.S.A. 77(1), 1980
PMID: 6987654
Transcriptional regulation of histidine biosynthesis genes in Corynebacterium glutamicum.
Jung S, Chun JY, Yim SH, Lee SS, Cheon CI, Song E, Lee MS., Can. J. Microbiol. 56(2), 2010
PMID: 20237580
Organization and analysis of the histidine biosynthetic genes from Corynebacterium glutamicum
Jung S-I, Chun JY, Yim S-H, Cheon C-I, Song E, Lee S-S, Lee M-S., 2009
The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.
Kalinowski J, Bathe B, Bartels D, Bischoff N, Bott M, Burkovski A, Dusch N, Eggeling L, Eikmanns BJ, Gaigalat L, Goesmann A, Hartmann M, Huthmacher K, Kramer R, Linke B, McHardy AC, Meyer F, Mockel B, Pfefferle W, Puhler A, Rey DA, Ruckert C, Rupp O, Sahm H, Wendisch VF, Wiegrabe I, Tauch A., J. Biotechnol. 104(1-3), 2003
PMID: 12948626
Molecular cloning and analysis of the hisH gene encoding glutamine amidotransferase from Corynebacterium glutamicum
Kim J, Lee M-S., 2001
Taxonomic study of glutamic acid accumulating bacteria, Micrococcus glutamicusnov. sp
Kinoshita S, Nakayama S, Akita S., 1958
Cloning of the histidine biosynthetic genes from Corynebacterium glutamicum: organization and analysis of the hisG and hisE genes.
Kwon JH, Chun JY, Lee HS, Cheon CI, Song ES, Min KH, Lee MS., Can. J. Microbiol. 46(9), 2000
PMID: 11006846
spoT, a new genetic locus involved in the stringent response in E. coli
Laffler T, Gallant J., 1974
The structure of Escherichia coli ATP-phosphoribosyltransferase: identification of substrate binding sites and mode of AMP inhibition.
Lohkamp B, McDermott G, Campbell SA, Coggins JR, Lapthorn AJ., J. Mol. Biol. 336(1), 2004
PMID: 14741209
Genome-based analysis of biosynthetic aminotransferase genes of Corynebacterium glutamicum.
McHardy AC, Tauch A, Ruckert C, Puhler A, Kalinowski J., J. Biotechnol. 104(1-3), 2003
PMID: 12948641
CDD: a Conserved Domain Database for the functional annotation of proteins.
Marchler-Bauer A, Lu S, Anderson JB, Chitsaz F, Derbyshire MK, DeWeese-Scott C, Fong JH, Geer LY, Geer RC, Gonzales NR, Gwadz M, Hurwitz DI, Jackson JD, Ke Z, Lanczycki CJ, Lu F, Marchler GH, Mullokandov M, Omelchenko MV, Robertson CL, Song JS, Thanki N, Yamashita RA, Zhang D, Zhang N, Zheng C, Bryant SH., Nucleic Acids Res. 39(Database issue), 2010
PMID: 21109532
Functional analysis of all aminotransferase proteins inferred from the genome sequence of Corynebacterium glutamicum.
Marienhagen J, Kennerknecht N, Sahm H, Eggeling L., J. Bacteriol. 187(22), 2005
PMID: 16267288
Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum.
Marienhagen J, Sandalova T, Sahm H, Eggeling L, Schneider G., Acta Crystallogr. D Biol. Crystallogr. 64(Pt 6), 2008
PMID: 18560156
The first enzyme in histidine biosynthesis: the nature of feedback inhibition by histidine
Martin RG., 1963
The one operon-one messenger theory of transcription
Martin RG., 1963
[147] Enzymes and intermediates of histidine biosynthesis in Salmonella typhimurium
Martin RG, Berberich MA, Ames BN, Davis WW, Goldberger RF, Yourno JD., 1971
Cloning of the ATP phosphoribosyl transferase gene of Corynebacterium glutamicum and application of the gene to L-histidine production.
Mizukami T, Hamu A, Ikeda M, Oka T, Katsumata R., Biosci. Biotechnol. Biochem. 58(4), 1994
PMID: 7764856
Synergistic inhibition of ATP phosphoribosyltransferase by guanosine tetraphosphate and histidine.
Morton DP, Parsons SM., Biochem. Biophys. Res. Commun. 74(1), 1977
PMID: 319792
Molecular cloning, overexpression, purification, crystallization and preliminary X-ray diffraction studies of histidinol phosphate aminotransferase (HisC2) from Mycobacterium tuberculosis
Nasir N, Vyas R, Chugh C, Ahangar MS, Biswal BK., 2012

Nelson DL, Cox MM., 2009
Nucleotide sequence of the attenuator region of the histidine operon of Escherichia coli K-12.
Di Nocera PP, Blasi F, Di Lauro R, Frunzio R, Bruni CB., Proc. Natl. Acad. Sci. U.S.A. 75(9), 1978
PMID: 360215
Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosis hisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23).
Nunes JE, Ducati RG, Breda A, Rosado LA, de Souza BM, Palma MS, Santos DS, Basso LA., Arch. Biochem. Biophys. 512(2), 2011
PMID: 21672513
Sigma factors and promoters in Corynebacterium glutamicum.
Patek M, Nesvera J., J. Biotechnol. 154(2-3), 2011
PMID: 21277915
The catalytic triad of serine peptidases.
Polgar L., Cell. Mol. Life Sci. 62(19-20), 2005
PMID: 16003488
Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway.
Rangarajan ES, Proteau A, Wagner J, Hung MN, Matte A, Cygler M., J. Biol. Chem. 281(49), 2006
PMID: 16966333
On the structure of histidine and its role in enzyme active sites
Rebek J., 1990
Internal promoters of the his operon in Salmonella typhimurium.
Schmid MB, Roth JR., J. Bacteriol. 153(2), 1983
PMID: 6296044
Complete genome sequence, lifestyle, and multi-drug resistance of the human pathogen Corynebacterium resistens DSM 45100 isolated from blood samples of a leukemia patient.
Schroder J, Maus I, Meyer K, Wordemann S, Blom J, Jaenicke S, Schneider J, Trost E, Tauch A., BMC Genomics 13(), 2012
PMID: 22524407
Comparative analysis of RNA regulatory elements of amino acid metabolism genes in Actinobacteria.
Seliverstov AV, Putzer H, Gelfand MS, Lyubetsky VA., BMC Microbiol. 5(), 2005
PMID: 16202131
An aminoacyl-tRNA synthetase paralog with a catalytic role in histidine biosynthesis.
Sissler M, Delorme C, Bond J, Ehrlich SD, Renault P, Francklyn C., Proc. Natl. Acad. Sci. U.S.A. 96(16), 1999
PMID: 10430882
INTERMEDIATES IN THE EARLY STEPS OF HISTIDINE BIOSYNTHESIS.
SMITH DW, AMES BN., J. Biol. Chem. 239(), 1964
PMID: 14213364
Aromatic amino acids
Sprenger GA., 2007
Histidine biosynthesis in plants.
Stepansky A, Leustek T., Amino Acids 30(2), 2006
PMID: 16547652
Reduced folate supply as a key to enhanced L-serine production by Corynebacterium glutamicum.
Stolz M, Peters-Wendisch P, Etterich H, Gerharz T, Faurie R, Sahm H, Fersterra H, Eggeling L., Appl. Environ. Microbiol. 73(3), 2006
PMID: 17142381
Relaxed rrn expression and amino acid requirement of a Corynebacterium glutamicum rel mutant defective in (p)ppGpp metabolism.
Tauch A, Wehmeier L, Gotker S, Puhler A, Kalinowski J., FEMS Microbiol. Lett. 201(1), 2001
PMID: 11445167
Studies on the quaternary structure of the first enzyme for histidine biosynthesis.
Tebar AR, Fernandez VM, Martin Del Rio R, Ballesteros AO., Experientia 29(12), 1973
PMID: 4358959
Biochemical bases for the antimetabolite action of L-serine hydroxamate.
Tosa T, Pizer LI., J. Bacteriol. 106(3), 1971
PMID: 4934072
Analysis of the Corynebacterium glutamicum dapA promoter.
Vasicova P, Patek M, Nesvera J, Sahm H, Eikmanns B., J. Bacteriol. 181(19), 1999
PMID: 10498736
Kinetic characterization of 4-amino 4-deoxychorismate synthase from Escherichia coli.
Viswanathan VK, Green JM, Nichols BP., J. Bacteriol. 177(20), 1995
PMID: 7592344
Comparative genomic analysis of T-box regulatory systems in bacteria.
Vitreschak AG, Mironov AA, Lyubetsky VA, Gelfand MS., RNA 14(4), 2008
PMID: 18359782
The role of the Corynebacterium glutamicum rel gene in (p)ppGpp metabolism.
Wehmeier L, Schafer A, Burkovski A, Kramer R, Mechold U, Malke H, Puhler A, Kalinowski J., Microbiology (Reading, Engl.) 144 ( Pt 7)(), 1998
PMID: 9695918

AUTHOR UNKNOWN, 2007
Biosynthesis of histidine
Winkler M., 1996
Cloning and sequencing of a 29 kb region of the Bacillus subtilis genome containing the hut and wapA loci.
Yoshida K, Sano H, Seki S, Oda M, Fujimura M, Fujita Y., Microbiology (Reading, Engl.) 141 ( Pt 2)(), 1995
PMID: 7704263
Structural biology of the purine biosynthetic pathway.
Zhang Y, Morar M, Ealick SE., Cell. Mol. Life Sci. 65(23), 2008
PMID: 18712276
The ncgl1108 (PheP (Cg)) gene encodes a new L-Phe transporter in Corynebacterium glutamicum.
Zhao Z, Ding JY, Li T, Zhou NY, Liu SJ., Appl. Microbiol. Biotechnol. 90(6), 2011
PMID: 21468701
Identification and characterization of γ-aminobutyric acid uptake system GabPCg (NCgl0464) in Corynebacterium glutamicum.
Zhao Z, Ding JY, Ma WH, Zhou NY, Liu SJ., Appl. Environ. Microbiol. 78(8), 2012
PMID: 22307305

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 23617600
PubMed | Europe PMC

Suchen in

Google Scholar