Photoswitchable DNA-binding properties of a photochromic spirooxazine derivative

Ihmels H, Mattay J, May F, Thomas L (2013)
Organic & Biomolecular Chemistry 11(31): 5184-5188.

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Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Abstract / Bemerkung
An N-methylphenanthrolinium-annelated spirooxazine derivative 2(SO) whose DNA-intercalating properties are reversibly changed by a photochromic reaction was prepared. Upon irradiation at 350 nm the spirooxazine is transformed to the corresponding photomerocyanine 2(PM) that binds to DNA. After irradiation with visible light the spirooxazine 2(SO), which exhibits no significant DNA-binding properties, is regained. The association of 2(PM) with DNA was examined by CD and absorption spectroscopy, fluorescent intercalator displacement and viscometric titration.
Erscheinungsjahr
Zeitschriftentitel
Organic & Biomolecular Chemistry
Band
11
Zeitschriftennummer
31
Seite
5184-5188
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Ihmels H, Mattay J, May F, Thomas L. Photoswitchable DNA-binding properties of a photochromic spirooxazine derivative. Organic & Biomolecular Chemistry. 2013;11(31):5184-5188.
Ihmels, H., Mattay, J., May, F., & Thomas, L. (2013). Photoswitchable DNA-binding properties of a photochromic spirooxazine derivative. Organic & Biomolecular Chemistry, 11(31), 5184-5188. doi:10.1039/c3ob40930a
Ihmels, H., Mattay, J., May, F., and Thomas, L. (2013). Photoswitchable DNA-binding properties of a photochromic spirooxazine derivative. Organic & Biomolecular Chemistry 11, 5184-5188.
Ihmels, H., et al., 2013. Photoswitchable DNA-binding properties of a photochromic spirooxazine derivative. Organic & Biomolecular Chemistry, 11(31), p 5184-5188.
H. Ihmels, et al., “Photoswitchable DNA-binding properties of a photochromic spirooxazine derivative”, Organic & Biomolecular Chemistry, vol. 11, 2013, pp. 5184-5188.
Ihmels, H., Mattay, J., May, F., Thomas, L.: Photoswitchable DNA-binding properties of a photochromic spirooxazine derivative. Organic & Biomolecular Chemistry. 11, 5184-5188 (2013).
Ihmels, Heiko, Mattay, Jochen, May, Florian, and Thomas, Laura. “Photoswitchable DNA-binding properties of a photochromic spirooxazine derivative”. Organic & Biomolecular Chemistry 11.31 (2013): 5184-5188.

7 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

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