Highly Enantioselective Reduction of α-Methylated Nitroalkenes

Burda E, Reß T, Winkler T, Giese C, Kostrov X, Huber T, Hummel W, Gröger H (2013)
Angewandte Chemie (International ed. in English) 52(35): 9323-9326.

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Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Abstract / Bemerkung
Highly selective: The reduction of α-methyl-substituted nitroalkenes succeeds in a highly enantioselective fashion with an ene reductase from Gluconobacter oxydans. Under optimized reaction conditions the desired nitroalkanes are formed with enantiomeric excesses of up to 95% in these biotransformations.
Erscheinungsjahr
Zeitschriftentitel
Angewandte Chemie (International ed. in English)
Band
52
Zeitschriftennummer
35
Seite
9323-9326
ISSN
PUB-ID

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Burda E, Reß T, Winkler T, et al. Highly Enantioselective Reduction of α-Methylated Nitroalkenes. Angewandte Chemie (International ed. in English). 2013;52(35):9323-9326.
Burda, E., Reß, T., Winkler, T., Giese, C., Kostrov, X., Huber, T., Hummel, W., et al. (2013). Highly Enantioselective Reduction of α-Methylated Nitroalkenes. Angewandte Chemie (International ed. in English), 52(35), 9323-9326. doi:10.1002/anie.201301814
Burda, E., Reß, T., Winkler, T., Giese, C., Kostrov, X., Huber, T., Hummel, W., and Gröger, H. (2013). Highly Enantioselective Reduction of α-Methylated Nitroalkenes. Angewandte Chemie (International ed. in English) 52, 9323-9326.
Burda, E., et al., 2013. Highly Enantioselective Reduction of α-Methylated Nitroalkenes. Angewandte Chemie (International ed. in English), 52(35), p 9323-9326.
E. Burda, et al., “Highly Enantioselective Reduction of α-Methylated Nitroalkenes”, Angewandte Chemie (International ed. in English), vol. 52, 2013, pp. 9323-9326.
Burda, E., Reß, T., Winkler, T., Giese, C., Kostrov, X., Huber, T., Hummel, W., Gröger, H.: Highly Enantioselective Reduction of α-Methylated Nitroalkenes. Angewandte Chemie (International ed. in English). 52, 9323-9326 (2013).
Burda, Edyta, Reß, Tina, Winkler, Till, Giese, Carolin, Kostrov, Xenia, Huber, Tobias, Hummel, Werner, and Gröger, Harald. “Highly Enantioselective Reduction of α-Methylated Nitroalkenes”. Angewandte Chemie (International ed. in English) 52.35 (2013): 9323-9326.

4 Zitationen in Europe PMC

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Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes.
Knaus T, Paul CE, Levy CW, de Vries S, Mutti FG, Hollmann F, Scrutton NS., J Am Chem Soc 138(3), 2016
PMID: 26727612
Chemoselective biocatalytic reduction of conjugated nitroalkenes: new application for an Escherichia coli BL21(DE3) expression strain.
Jovanovic P, Jeremic S, Djokic L, Savic V, Radivojevic J, Maslak V, Ivkovic B, Vasiljevic B, Nikodinovic-Runic J., Enzyme Microb Technol 60(), 2014
PMID: 24835095

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