Forest alignment with affine gaps and anchors, applied in RNA structure comparison

Schirmer S, Giegerich R (2013)
Theoretical Computer Science 483: 51-67.

Journal Article | Published | English

No fulltext has been uploaded

Abstract
We present two enhancements to Jiang's tree alignment algorithm, motivated by experience with its use for RNA structure alignment. One enhancement is the introduction of an affine gap model, which can be accommodated with a runtime increase by a constant factor. The second enhancement is a speed-up of the alignment algorithm when certain nodes in the trees are pre-aligned by a so-called anchoring. Both enhancements are included in a new implementation of the tool RNAFORESTER. We evaluate the new algorithm with two applications related to RNA secondary structure analysis. Based on our experience, we suggest a new formulation of the tree alignment model, based on regular tree languages and rewrite rules. (C) 2012 Elsevier B.V. All rights reserved.
Publishing Year
ISSN
PUB-ID

Cite this

Schirmer S, Giegerich R. Forest alignment with affine gaps and anchors, applied in RNA structure comparison. Theoretical Computer Science. 2013;483:51-67.
Schirmer, S., & Giegerich, R. (2013). Forest alignment with affine gaps and anchors, applied in RNA structure comparison. Theoretical Computer Science, 483, 51-67.
Schirmer, S., and Giegerich, R. (2013). Forest alignment with affine gaps and anchors, applied in RNA structure comparison. Theoretical Computer Science 483, 51-67.
Schirmer, S., & Giegerich, R., 2013. Forest alignment with affine gaps and anchors, applied in RNA structure comparison. Theoretical Computer Science, 483, p 51-67.
S. Schirmer and R. Giegerich, “Forest alignment with affine gaps and anchors, applied in RNA structure comparison”, Theoretical Computer Science, vol. 483, 2013, pp. 51-67.
Schirmer, S., Giegerich, R.: Forest alignment with affine gaps and anchors, applied in RNA structure comparison. Theoretical Computer Science. 483, 51-67 (2013).
Schirmer, Stefanie, and Giegerich, Robert. “Forest alignment with affine gaps and anchors, applied in RNA structure comparison”. Theoretical Computer Science 483 (2013): 51-67.
This data publication is cited in the following publications:
This publication cites the following data publications:

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Search this title in

Google Scholar