Incidence of maternal Toxoplasma infections in pregnancy in Upper Austria, 2000-2007

Sagel U, Krämer A, Mikolajczyk RT (2011)
BMC Infectious Diseases 11(1).

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UNLABELLED: ABSTRACT: BACKGROUND: Despite three decades of prenatal screening program for toxoplasmosis in Austria, population-based estimates for the incidence of maternal infections with Toxoplasma gondii during pregnancy are lacking. We studied the incidence of primary maternal infections during pregnancy in the Federal State of Upper Austria. METHODS: Screening tests for 63,416 women and over 90,000 pregnancies (more than 84.5% of pregnancies in the studied region) in the time period between 01.01.2000 and 31.12.2007 were analysed. The incidence of toxoplasmosis was estimated indirectly by binomial and directly by interval censored regression. RESULTS: During the studied period, 66 acute infections (risk of 0.07% per pregnancy) were detected, but only 29.8% of seronegative women were tested at least three times during their pregnancies. The seroprevalence of Toxoplasma antibodies among all tested women was 31%. Indirectly estimated incidence (from differences in prevalence by age) was 0.5% per pregnancy, while directly estimated incidence (interval censored regression) was 0.17% per pregnancy (95% confidence interval: 0.13-0.21%). CONCLUSIONS: Calculating incidence from observed infections results in severe underreporting due to many missed tests and potential diagnostic problems. Using statistical modelling, we estimated primary toxoplasmosis to occur in 0.17% (0.13-0.21%) of all pregnancies in Upper Austria.
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Sagel U, Krämer A, Mikolajczyk RT. Incidence of maternal Toxoplasma infections in pregnancy in Upper Austria, 2000-2007. BMC Infectious Diseases. 2011;11(1).
Sagel, U., Krämer, A., & Mikolajczyk, R. T. (2011). Incidence of maternal Toxoplasma infections in pregnancy in Upper Austria, 2000-2007. BMC Infectious Diseases, 11(1).
Sagel, U., Krämer, A., and Mikolajczyk, R. T. (2011). Incidence of maternal Toxoplasma infections in pregnancy in Upper Austria, 2000-2007. BMC Infectious Diseases 11.
Sagel, U., Krämer, A., & Mikolajczyk, R.T., 2011. Incidence of maternal Toxoplasma infections in pregnancy in Upper Austria, 2000-2007. BMC Infectious Diseases, 11(1).
U. Sagel, A. Krämer, and R.T. Mikolajczyk, “Incidence of maternal Toxoplasma infections in pregnancy in Upper Austria, 2000-2007”, BMC Infectious Diseases, vol. 11, 2011.
Sagel, U., Krämer, A., Mikolajczyk, R.T.: Incidence of maternal Toxoplasma infections in pregnancy in Upper Austria, 2000-2007. BMC Infectious Diseases. 11, (2011).
Sagel, Ulrich, Krämer, Alexander, and Mikolajczyk, Rafael T. “Incidence of maternal Toxoplasma infections in pregnancy in Upper Austria, 2000-2007”. BMC Infectious Diseases 11.1 (2011).
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Time patterns of recurrences and factors predisposing for a higher risk of recurrence of ocular toxoplasmosis.
Reich M, Ruppenstein M, Becker MD, Mackensen F., Retina (Philadelphia, Pa.) 35(4), 2015
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The Austrian Toxoplasmosis Register, 1992-2008.
Prusa AR, Kasper DC, Pollak A, Gleiss A, Waldhoer T, Hayde M., Clin. Infect. Dis. 60(2), 2015
PMID: 25216688
Survey of obstetrician-gynecologists in the United States about toxoplasmosis: 2012 update.
Davis SM, Anderson BL, Schulkin J, Jones K, Vanden Eng J, Jones JL., Arch. Gynecol. Obstet. 291(3), 2015
PMID: 25205181
Neglected parasitic infections in the United States: toxoplasmosis.
Jones JL, Parise ME, Fiore AE., Am. J. Trop. Med. Hyg. 90(5), 2014
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Epidemiology of Toxoplasma and CMV serology and of GBS colonization in pregnancy and neonatal outcome in a Sicilian population.
Puccio G, Cajozzo C, Canduscio LA, Cino L, Romano A, Schimmenti MG, Giuffre M, Corsello G., Ital J Pediatr 40(), 2014
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Age-associated prevalence of Toxoplasma gondii in 8281 pregnant women in Poland between 2004 and 2012.
Nowakowska D, Wujcicka W, Sobala W, Spiewak E, Gaj Z, Wilczynski J., Epidemiol. Infect. 142(3), 2014
PMID: 23721799
"Blind periods" in screening for toxoplasmosis in pregnancy in Austria - a debate.
Sagel U, Kramer A, Mikolajczyk RT., BMC Infect. Dis. 12(), 2012
PMID: 22591211

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