Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine

Miech C, Dierks T, Selmer T, Figura von K, Schmidt B (1998)
JOURNAL OF BIOLOGICAL CHEMISTRY 273(9): 4835-4837.

Download
No fulltext has been uploaded. References only!
Journal Article | Published | English

No fulltext has been uploaded

Author
; ; ; ;
Abstract
Eukaryotic sulfatases share an unusual posttranslational protein modification, which converts a cysteine into alpha-formylglycine. The alpha-formylglycine is essential for the catalytic activity. Klebsiella pneumoniae expresses an inducible arylsulfatase for which the DNA predicts a serine at the position occupied by the alpha-formylglycine residue in eukaryotic sulfatases. Structural analysis showed that the majority of the arylsulfatase polypeptides from K. pneumoniae carries the alpha-formylglycine, whereas the remaining arylsulfatase polypeptides contain the predicted serine residue. This demonstrates the evolutionary conservation between prokaryotes and eukaryotes of this novel protein modification that so far has been found only in sulfatases. alpha-Formylglycine in Klebsiella is generated from a serine and not from a cysteine as in eukaryotes.
Publishing Year
ISSN
PUB-ID

Cite this

Miech C, Dierks T, Selmer T, Figura von K, Schmidt B. Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine. JOURNAL OF BIOLOGICAL CHEMISTRY. 1998;273(9):4835-4837.
Miech, C., Dierks, T., Selmer, T., Figura von, K., & Schmidt, B. (1998). Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine. JOURNAL OF BIOLOGICAL CHEMISTRY, 273(9), 4835-4837. doi:10.1074/jbc.273.9.4835
Miech, C., Dierks, T., Selmer, T., Figura von, K., and Schmidt, B. (1998). Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine. JOURNAL OF BIOLOGICAL CHEMISTRY 273, 4835-4837.
Miech, C., et al., 1998. Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine. JOURNAL OF BIOLOGICAL CHEMISTRY, 273(9), p 4835-4837.
C. Miech, et al., “Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine”, JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, 1998, pp. 4835-4837.
Miech, C., Dierks, T., Selmer, T., Figura von, K., Schmidt, B.: Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine. JOURNAL OF BIOLOGICAL CHEMISTRY. 273, 4835-4837 (1998).
Miech, C, Dierks, Thomas, Selmer, T, Figura von, K, and Schmidt, B. “Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine”. JOURNAL OF BIOLOGICAL CHEMISTRY 273.9 (1998): 4835-4837.
This data publication is cited in the following publications:
This publication cites the following data publications:

34 Citations in Europe PMC

Data provided by Europe PubMed Central.

Structural distortions due to missense mutations in human formylglycine-generating enzyme leading to multiple sulfatase deficiency.
Meshach Paul D, Chadah T, Senthilkumar B, Sethumadhavan R, Rajasekaran R., J. Biomol. Struct. Dyn. (), 2017
PMID: 29048999
Characterization of an arylsulfatase from a mutant library of Pseudoalteromonas carrageenovora arylsulfatase.
Zhu Y, Liu H, Qiao C, Li L, Jiang Z, Xiao A, Ni H., Int. J. Biol. Macromol. 96(), 2017
PMID: 27940339
Detection, production, and application of microbial arylsulfatases.
Stressler T, Seitl I, Kuhn A, Fischer L., Appl. Microbiol. Biotechnol. 100(21), 2016
PMID: 27654655
Enzymatic desulfation of the red seaweeds agar by Marinomonas arylsulfatase.
Wang X, Duan D, Fu X., Int. J. Biol. Macromol. 93(Pt A), 2016
PMID: 27521846
Mucopolysaccharidosis enzyme production by bone marrow and dental pulp derived human mesenchymal stem cells.
Jackson M, Derrick Roberts A, Martin E, Rout-Pitt N, Gronthos S, Byers S., Mol. Genet. Metab. 114(4), 2015
PMID: 25748347
Deep Genotyping of the IDS Gene in Colombian Patients with Hunter Syndrome.
Galvis J, Gonzalez J, Uribe A, Velasco H., JIMD Rep 19(), 2015
PMID: 25681085
Low-scale expression and purification of an active putative iduronate 2-sulfate sulfatase-Like enzyme from Escherichia coli K12.
Morales-Alvarez ED, Rivera-Hoyos CM, Baena-Moncada AM, Landazuri P, Poutou-Pinales RA, Saenz-Suarez H, Barrera LA, Echeverri-Pena OY., J. Microbiol. 51(2), 2013
PMID: 23625223
Evaluation of sulfatase-directed quinone methide traps for proteomics.
Lenger J, Schroder M, Ennemann EC, Muller B, Wong CH, Noll T, Dierks T, Hanson SR, Sewald N., Bioorg. Med. Chem. 20(2), 2012
PMID: 21570853

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 9478923
PubMed | Europe PMC

Search this title in

Google Scholar