The development of new monometallic bifunctional catalysts with Lewis acid and Lewis base properties, and their application in asymmetric cyanation reactions

Gröger H (2001)
Chemistry 7(24): 5246-5251.

Journal Article | Published | English

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Abstract
Bifunctional catalysts can drastically improve the efficiency of asymmetric processes with respect to enantioselectivity and/or conversion rate. A new type of chiral bifunctional catalyst has been developed recently in the Shibasaki group that contains both Lewis acid and Lewis base moieties. These monometallic and bifunctional phosphinoyl-containing catalysts are able to coordinate both nucleophilic and electrophilic substrates in the transition state. Several successful applications of this new catalytic concept in the field of asymmetric cyanation reactions have already been reported, for example, the asymmetric hydrocyanation of aldehydes and imines as well as the asymmetric Reissert reaction. The development and principle of this catalytic concept as well as main applications thereof are reviewed in this article.
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Gröger H. The development of new monometallic bifunctional catalysts with Lewis acid and Lewis base properties, and their application in asymmetric cyanation reactions. Chemistry. 2001;7(24):5246-5251.
Gröger, H. (2001). The development of new monometallic bifunctional catalysts with Lewis acid and Lewis base properties, and their application in asymmetric cyanation reactions. Chemistry, 7(24), 5246-5251.
Gröger, H. (2001). The development of new monometallic bifunctional catalysts with Lewis acid and Lewis base properties, and their application in asymmetric cyanation reactions. Chemistry 7, 5246-5251.
Gröger, H., 2001. The development of new monometallic bifunctional catalysts with Lewis acid and Lewis base properties, and their application in asymmetric cyanation reactions. Chemistry, 7(24), p 5246-5251.
H. Gröger, “The development of new monometallic bifunctional catalysts with Lewis acid and Lewis base properties, and their application in asymmetric cyanation reactions”, Chemistry, vol. 7, 2001, pp. 5246-5251.
Gröger, H.: The development of new monometallic bifunctional catalysts with Lewis acid and Lewis base properties, and their application in asymmetric cyanation reactions. Chemistry. 7, 5246-5251 (2001).
Gröger, Harald. “The development of new monometallic bifunctional catalysts with Lewis acid and Lewis base properties, and their application in asymmetric cyanation reactions”. Chemistry 7.24 (2001): 5246-5251.
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44 References

Data provided by Europe PubMed Central.

Catalytic Asymmetric Cyanohydrin Synthesis
North, Synlett 1993(11), 1993
Synthesis and Reactions of Optically Active Cyanohydrins
Effenberger, Angewandte Chemie International Edition in English 33(1516), 1994
Polyoxometalate Chemistry: An Old Field with New Dimensions in Several Disciplines
Pope, Angewandte Chemie International Edition in English 30(1), 1991
A New Multifunctional Heterobimetallic Asymmetric Catalyst for Michael Additions and Tandem Michael–Aldol Reactions
Arai, Angewandte Chemie International Edition in English 35(1), 1996
Asymmetric Catalysis with Heterobimetallic Compounds
Shibasaki, Angewandte Chemie International Edition in English 36(12), 1997

Ito, Journal of the American Chemical Society 108(20), 1986
Enantioselective Total Synthesis of Epothilone A Using Multifunctional Asymmetric Catalyses
Sawada, Angewandte Chemie 112(1), 2000
A Catalytic Asymmetric Strecker-Type Reaction: Interesting Reactivity Difference between TMSCN and HCN
Takamura, Angewandte Chemie 112(9), 2000
Chemical Biology of Epothilones
Nicolaou, Angewandte Chemie International Edition 37(15), 1998
Neue Entwicklungen bei der katalytisch-asymmetrischen Strecker-Reaktion
Yet, Angewandte Chemie 113(5), 2001
Recent Developments in Catalytic Asymmetric Strecker-Type Reactions
Yet, Angewandte Chemie International Edition 40(5), 2001
A Practical Synthesis of threo-3-Amino-2-hydroxycarboxylic Acids.
Matsuda, Bulletin of the Chemical Society of Japan 65(2), 1992
Enantioselektive Addition von Organometallreagentien an Carbonylverbindungen: Übertragung, Vervielfältigung und Verstärkung der Chiralität
Noyori, Angewandte Chemie 103(1), 1991
Synthese und Reaktionen optisch aktiver Cyanhydrine
Effenberger, Angewandte Chemie 106(15-16), 1994
Ein neuartiger multifunktioneller asymmetrischer Hetero-Dimetall-Katalysator für Michael-Additionen und Tandem-Michael-Aldol-Reaktionen
Arai, Angewandte Chemie 108(1), 1996
Asymmetrische Zweizentren-Katalyse – von der Natur lernen
Steinhagen, Angewandte Chemie 108(20), 1996
Asymmetrische Katalyse mit Hetero-Dimetall-Verbindungen
Shibasaki, Angewandte Chemie 109(12), 1997
Chiral Heterobimetallic Lanthanoid Complexes: Highly Efficient Multifunctional Catalysts for the Asymmetric Formation of C-C, C-O, and C-P Bonds
Shibasaki, 1999

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