The first aminoacylase-catalyzed enantioselective synthesis of aromatic beta-amino acids

Gröger H, Trauthwein H, Buchholz S, Drauz K, Sacherer C, Godfrin S, Werner H (2004)
Org. Biomol. Chemistry 2(14): 1977-1978.

Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Autor
; ; ; ; ; ;
Abstract / Bemerkung
The first aminoacylase-catalyzed enantioselective synthesis of aromatic beta-amino acids is reported. The presence of an N-chloroacetyl group as acyl group in the substrate as well as the use of porcine kidney acylase I as a suitable enzyme component are prerequisites for this resolution process whereby optically active beta-amino acids are formed with high enantioselectivities of >98% ee.
Erscheinungsjahr
Zeitschriftentitel
Org. Biomol. Chemistry
Band
2
Zeitschriftennummer
14
Seite
1977-1978
ISSN
eISSN
PUB-ID

Zitieren

Gröger H, Trauthwein H, Buchholz S, et al. The first aminoacylase-catalyzed enantioselective synthesis of aromatic beta-amino acids. Org. Biomol. Chemistry. 2004;2(14):1977-1978.
Gröger, H., Trauthwein, H., Buchholz, S., Drauz, K., Sacherer, C., Godfrin, S., & Werner, H. (2004). The first aminoacylase-catalyzed enantioselective synthesis of aromatic beta-amino acids. Org. Biomol. Chemistry, 2(14), 1977-1978. doi:10.1039/b406380e
Gröger, H., Trauthwein, H., Buchholz, S., Drauz, K., Sacherer, C., Godfrin, S., and Werner, H. (2004). The first aminoacylase-catalyzed enantioselective synthesis of aromatic beta-amino acids. Org. Biomol. Chemistry 2, 1977-1978.
Gröger, H., et al., 2004. The first aminoacylase-catalyzed enantioselective synthesis of aromatic beta-amino acids. Org. Biomol. Chemistry, 2(14), p 1977-1978.
H. Gröger, et al., “The first aminoacylase-catalyzed enantioselective synthesis of aromatic beta-amino acids”, Org. Biomol. Chemistry, vol. 2, 2004, pp. 1977-1978.
Gröger, H., Trauthwein, H., Buchholz, S., Drauz, K., Sacherer, C., Godfrin, S., Werner, H.: The first aminoacylase-catalyzed enantioselective synthesis of aromatic beta-amino acids. Org. Biomol. Chemistry. 2, 1977-1978 (2004).
Gröger, Harald, Trauthwein, Harald, Buchholz, Stefan, Drauz, Karlheinz, Sacherer, Christiane, Godfrin, Sylvie, and Werner, Helge. “The first aminoacylase-catalyzed enantioselective synthesis of aromatic beta-amino acids”. Org. Biomol. Chemistry 2.14 (2004): 1977-1978.

11 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Enzymatic synthesis of chiral γ-amino acids using ω-transaminase.
Shon M, Shanmugavel R, Shin G, Mathew S, Lee SH, Yun H., Chem Commun (Camb) 50(84), 2014
PMID: 25207334
Bacterial β-aminopeptidases: structural insights and applications for biocatalysis.
Heck T, Geueke B, Kohler HP., Chem Biodivers 9(11), 2012
PMID: 23161625
Kinetic resolution of aromatic β-amino acids by ω-transaminase.
Bea HS, Park HJ, Lee SH, Yun H., Chem Commun (Camb) 47(20), 2011
PMID: 21487615
Kinetic resolution of aliphatic beta-amino acid amides by beta-aminopeptidases.
Heck T, Seebach D, Osswald S, Ter Wiel MK, Kohler HP, Geueke B., Chembiochem 10(9), 2009
PMID: 19449346

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 15254623
PubMed | Europe PMC

Suchen in

Google Scholar