High-quality genome sequence of Pichia pastoris CBS7435

Küberl A, Schneider J, Thallinger GG, Anderl I, Wibberg D, Hajek T, Jaenicke S, Brinkrolf K, Goesmann A, Szczepanowski R, Pühler A, et al. (2011)
Journal of Biotechnology 154(4): 312-320.

Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Autor
Abstract / Bemerkung
The methylotrophic yeast Pichia pastoris (Komagataella phaffii) CBS7435 is the parental strain of commonly used P. pastoris recombinant protein production hosts making it well suited for improving the understanding of associated genomic features. Here, we present a 9.35Mbp high-quality genome sequence of P. pastoris CBS7435 established by a combination of 454 and Illumina sequencing. An automatic annotation of the genome sequence yielded 5007 protein-coding genes, 124 tRNAs and 29 rRNAs. Moreover, we report the complete DNA sequence of the first mitochondrial genome of a methylotrophic yeast. Fifteen genes encoding proteins, 2 rRNA and 25 tRNA loci were identified on the 35.7kbp circular, mitochondrial DNA. Furthermore, the architecture of the putative alpha mating factor protein of P. pastoris CBS7435 turned out to be more complex than the corresponding protein of Saccharomyces cerevisiae. Copyright 2011 Elsevier B.V. All rights reserved.
Erscheinungsjahr
Zeitschriftentitel
Journal of Biotechnology
Band
154
Zeitschriftennummer
4
Seite
312-320
ISSN
PUB-ID

Zitieren

Küberl A, Schneider J, Thallinger GG, et al. High-quality genome sequence of Pichia pastoris CBS7435. Journal of Biotechnology. 2011;154(4):312-320.
Küberl, A., Schneider, J., Thallinger, G. G., Anderl, I., Wibberg, D., Hajek, T., Jaenicke, S., et al. (2011). High-quality genome sequence of Pichia pastoris CBS7435. Journal of Biotechnology, 154(4), 312-320. doi:10.1016/j.jbiotec.2011.04.014
Küberl, A., Schneider, J., Thallinger, G. G., Anderl, I., Wibberg, D., Hajek, T., Jaenicke, S., Brinkrolf, K., Goesmann, A., Szczepanowski, R., et al. (2011). High-quality genome sequence of Pichia pastoris CBS7435. Journal of Biotechnology 154, 312-320.
Küberl, A., et al., 2011. High-quality genome sequence of Pichia pastoris CBS7435. Journal of Biotechnology, 154(4), p 312-320.
A. Küberl, et al., “High-quality genome sequence of Pichia pastoris CBS7435”, Journal of Biotechnology, vol. 154, 2011, pp. 312-320.
Küberl, A., Schneider, J., Thallinger, G.G., Anderl, I., Wibberg, D., Hajek, T., Jaenicke, S., Brinkrolf, K., Goesmann, A., Szczepanowski, R., Pühler, A., Schwab, H., Glieder, A., Pichler, H.: High-quality genome sequence of Pichia pastoris CBS7435. Journal of Biotechnology. 154, 312-320 (2011).
Küberl, Andreas, Schneider, Jessica, Thallinger, Gerhard G., Anderl, Ingund, Wibberg, Daniel, Hajek, Tanja, Jaenicke, Sebastian, Brinkrolf, Karina, Goesmann, Alexander, Szczepanowski, Rafael, Pühler, Alfred, Schwab, Helmut, Glieder, Anton, and Pichler, Harald. “High-quality genome sequence of Pichia pastoris CBS7435”. Journal of Biotechnology 154.4 (2011): 312-320.

66 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Lipidome and proteome of lipid droplets from the methylotrophic yeast Pichia pastoris.
Ivashov VA, Grillitsch K, Koefeler H, Leitner E, Baeumlisberger D, Karas M, Daum G., Biochim Biophys Acta 1831(2), 2013
PMID: 23041514
Biotechnology of non-Saccharomyces yeasts--the ascomycetes.
Johnson EA., Appl Microbiol Biotechnol 97(2), 2013
PMID: 23184219
Complete DNA sequence of Kuraishia capsulata illustrates novel genomic features among budding yeasts (Saccharomycotina).
Morales L, Noel B, Porcel B, Marcet-Houben M, Hullo MF, Sacerdot C, Tekaia F, Leh-Louis V, Despons L, Khanna V, Aury JM, Barbe V, Couloux A, Labadie K, Pelletier E, Souciet JL, Boekhout T, Gabaldon T, Wincker P, Dujon B., Genome Biol Evol 5(12), 2013
PMID: 24317973
Metabolic reconstruction and flux analysis of industrial Pichia yeasts.
Chung BK, Lakshmanan M, Klement M, Ching CB, Lee DY., Appl Microbiol Biotechnol 97(5), 2013
PMID: 23339015
Pichia pastoris: protein production host and model organism for biomedical research.
Gasser B, Prielhofer R, Marx H, Maurer M, Nocon J, Steiger M, Puxbaum V, Sauer M, Mattanovich D., Future Microbiol 8(2), 2013
PMID: 23374125
New opportunities by synthetic biology for biopharmaceutical production in Pichia pastoris.
Vogl T, Hartner FS, Glieder A., Curr Opin Biotechnol 24(6), 2013
PMID: 23522654
Identification of triacylglycerol and steryl ester synthases of the methylotrophic yeast Pichia pastoris.
Ivashov VA, Zellnig G, Grillitsch K, Daum G., Biochim Biophys Acta 1831(6), 2013
PMID: 23524242
The secretory pathway: exploring yeast diversity.
Delic M, Valli M, Graf AB, Pfeffer M, Mattanovich D, Gasser B., FEMS Microbiol Rev 37(6), 2013
PMID: 23480475
Protein secretion in Pichia pastoris and advances in protein production.
Damasceno LM, Huang CJ, Batt CA., Appl Microbiol Biotechnol 93(1), 2012
PMID: 22057543
Mitochondrial genomes of yeasts of the Yarrowia clade.
Gaillardin C, Neuvéglise C, Kerscher S, Nicaud JM., FEMS Yeast Res 12(3), 2012
PMID: 22188421
Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway.
Krainer FW, Dietzsch C, Hajek T, Herwig C, Spadiut O, Glieder A., Microb Cell Fact 11(), 2012
PMID: 22330134
Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology.
Näätsaari L, Mistlberger B, Ruth C, Hajek T, Hartner FS, Glieder A., PLoS One 7(6), 2012
PMID: 22768112

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 21575661
PubMed | Europe PMC

Suchen in

Google Scholar