A Hybrid System for Cell Detection in Digital Micrographs

Nattkemper TW, Schubert W, Hermann T, Ritter H (2004)
In: Biomedical Engineering, Proc. Tilg B (Ed);417. Innsbruck, Austria: ACTA Press.

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Conference Paper | Published | English
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Tilg, B.
Abstract
To analyze large sets of digital micrographs from high-throughput screening studies with constant accuracy, advanced image processing algorithms are necessary. In the literature, systems have been proposed applying modelbased fitting algorithms, morphological operators and artificial neural networks (ANN). Because single approaches show limited performance, we propose a hybrid system that combines the Hough transform with a multi-layer perceptron (MLP) network. Our results show, that the combination of both approaches improves the performance and the positions of cell bodies are obtained with increased sensitivity and positive predictive value.
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Nattkemper TW, Schubert W, Hermann T, Ritter H. A Hybrid System for Cell Detection in Digital Micrographs. In: Tilg B, ed. Biomedical Engineering, Proc. Vol 417. Innsbruck, Austria: ACTA Press; 2004.
Nattkemper, T. W., Schubert, W., Hermann, T., & Ritter, H. (2004). A Hybrid System for Cell Detection in Digital Micrographs. In B. Tilg (Ed.), Biomedical Engineering, Proc. (Vol. 417). Innsbruck, Austria: ACTA Press.
Nattkemper, T. W., Schubert, W., Hermann, T., and Ritter, H. (2004). “A Hybrid System for Cell Detection in Digital Micrographs” in Biomedical Engineering, Proc., ed. B. Tilg, vol. 417, (Innsbruck, Austria: ACTA Press).
Nattkemper, T.W., et al., 2004. A Hybrid System for Cell Detection in Digital Micrographs. In B. Tilg, ed. Biomedical Engineering, Proc. no.417 Innsbruck, Austria: ACTA Press.
T.W. Nattkemper, et al., “A Hybrid System for Cell Detection in Digital Micrographs”, Biomedical Engineering, Proc., B. Tilg, ed., vol. 417, Innsbruck, Austria: ACTA Press, 2004.
Nattkemper, T.W., Schubert, W., Hermann, T., Ritter, H.: A Hybrid System for Cell Detection in Digital Micrographs. In: Tilg, B. (ed.) Biomedical Engineering, Proc. 417, ACTA Press, Innsbruck, Austria (2004).
Nattkemper, Tim Wilhelm, Schubert, Walter, Hermann, Thomas, and Ritter, Helge. “A Hybrid System for Cell Detection in Digital Micrographs”. Biomedical Engineering, Proc. Ed. B. Tilg. Innsbruck, Austria: ACTA Press, 2004.Vol. 417.
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