Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate

Kato O, Youn J-W, Stansen KC, Matsui D, Oikawa T, Wendisch VF (2010)
BMC Microbiology 10(1): 321.

Download
OA
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Volltext vorhanden für diesen Nachweis
Autor
; ; ; ; ;
Abstract / Bemerkung
Background: Corynebacterium glutamicum is able to grow with lactate as sole or combined carbon and energy source. Quinone-dependent L-lactate dehydrogenase LldD is known to be essential for utilization of L-lactate by C. glutamicum. D-lactate also serves as sole carbon source for C. glutamicum ATCC 13032. Results: Here, the gene cg1027 was shown to encode the quinone-dependent D-lactate dehydrogenase (Dld) by enzymatic analysis of the protein purified from recombinant E. coli. The absorption spectrum of purified Dld indicated the presence of FAD as bound cofactor. Inactivation of dld resulted in the loss of the ability to grow with D-lactate, which could be restored by plasmid-borne expression of dld. Heterologous expression of dld from C. glutamicum ATCC 13032 in C. efficiens enabled this species to grow with D-lactate as sole carbon source. Homologs of dld of C. glutamicum ATCC 13032 are not encoded in the sequenced genomes of other corynebacteria and mycobacteria. However, the dld locus of C. glutamicum ATCC 13032 shares 2367 bp of 2372 bp identical nucleotides with the dld locus of Propionibacterium freudenreichii subsp. shermanii, a bacterium used in Swiss-type cheese making. Both loci are flanked by insertion sequences of the same family suggesting a possible event of horizontal gene transfer. Conclusions: Cg1067 encodes quinone-dependent D-lactate dehydrogenase Dld of Corynebacterium glutamicum. Dld is essential for growth with D-lactate as sole carbon source. The genomic region of dld likely has been acquired by horizontal gene transfer.
Erscheinungsjahr
Zeitschriftentitel
BMC Microbiology
Band
10
Zeitschriftennummer
1
Seite
321
ISSN
Finanzierungs-Informationen
Article Processing Charge funded by the Deutsche Forschungsgemeinschaft and the Open Access Publication Fund of Bielefeld University.
PUB-ID

Zitieren

Kato O, Youn J-W, Stansen KC, Matsui D, Oikawa T, Wendisch VF. Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate. BMC Microbiology. 2010;10(1):321.
Kato, O., Youn, J. - W., Stansen, K. C., Matsui, D., Oikawa, T., & Wendisch, V. F. (2010). Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate. BMC Microbiology, 10(1), 321. doi:10.1186/1471-2180-10-321
Kato, O., Youn, J. - W., Stansen, K. C., Matsui, D., Oikawa, T., and Wendisch, V. F. (2010). Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate. BMC Microbiology 10, 321.
Kato, O., et al., 2010. Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate. BMC Microbiology, 10(1), p 321.
O. Kato, et al., “Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate”, BMC Microbiology, vol. 10, 2010, pp. 321.
Kato, O., Youn, J.-W., Stansen, K.C., Matsui, D., Oikawa, T., Wendisch, V.F.: Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate. BMC Microbiology. 10, 321 (2010).
Kato, Osamu, Youn, Jung-Won, Stansen, K. C., Matsui, Daisuke, Oikawa, Tadao, and Wendisch, Volker F. “Quinone-dependent D-lactate dehydrogenase Dld (Cg1027) is essential for growth of Corynebacterium glutamicum on D-lactate”. BMC Microbiology 10.1 (2010): 321.
Alle Dateien verfügbar unter der/den folgenden Lizenz(en):
Copyright Statement:
This Item is protected by copyright and/or related rights. [...]
Volltext(e)
Access Level
OA Open Access
Zuletzt Hochgeladen
2015-12-11T14:05:27Z

18 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

CRP Regulates D-Lactate Oxidation in Shewanella oneidensis MR-1.
Kasai T, Kouzuma A, Watanabe K., Front Microbiol 8(), 2017
PMID: 28559887
Coexistence of two d-lactate-utilizing systems in Pseudomonas putida KT2440.
Zhang Y, Jiang T, Sheng B, Long Y, Gao C, Ma C, Xu P., Environ Microbiol Rep 8(5), 2016
PMID: 27264531
Utilization of D-Lactate as an Energy Source Supports the Growth of Gluconobacter oxydans.
Sheng B, Xu J, Zhang Y, Jiang T, Deng S, Kong J, Gao C, Ma C, Xu P., Appl Environ Microbiol 81(12), 2015
PMID: 25862219
Engineering of Corynebacterium glutamicum for growth and L-lysine and lycopene production from N-acetyl-glucosamine.
Matano C, Uhde A, Youn JW, Maeda T, Clermont L, Marin K, Krämer R, Wendisch VF, Seibold GM., Appl Microbiol Biotechnol 98(12), 2014
PMID: 24668244
Microbial lactate utilization: enzymes, pathogenesis, and regulation.
Jiang T, Gao C, Ma C, Xu P., Trends Microbiol 22(10), 2014
PMID: 24950803
Accelerated pentose utilization by Corynebacterium glutamicum for accelerated production of lysine, glutamate, ornithine and putrescine.
Meiswinkel TM, Gopinath V, Lindner SN, Nampoothiri KM, Wendisch VF., Microb Biotechnol 6(2), 2013
PMID: 23164409
Conversion of Corynebacterium glutamicum from an aerobic respiring to an aerobic fermenting bacterium by inactivation of the respiratory chain.
Koch-Koerfges A, Pfelzer N, Platzen L, Oldiges M, Bott M., Biochim Biophys Acta 1827(6), 2013
PMID: 23416842
Corynebacterium glutamicum as a potent biocatalyst for the bioconversion of pentose sugars to value-added products.
Gopinath V, Murali A, Dhar KS, Nampoothiri KM., Appl Microbiol Biotechnol 93(1), 2012
PMID: 22094976
Engineering Corynebacterium glutamicum for the production of pyruvate.
Wieschalka S, Blombach B, Eikmanns BJ., Appl Microbiol Biotechnol 94(2), 2012
PMID: 22228312
NAD-independent L-lactate dehydrogenase is required for L-lactate utilization in Pseudomonas stutzeri SDM.
Gao C, Jiang T, Dou P, Ma C, Li L, Kong J, Xu P., PLoS One 7(5), 2012
PMID: 22574176
Metabolic engineering of Corynebacterium glutamicum aimed at alternative carbon sources and new products.
Zahoor A, Lindner SN, Wendisch VF., Comput Struct Biotechnol J 3(), 2012
PMID: 24688664
Amino acid production from rice straw and wheat bran hydrolysates by recombinant pentose-utilizing Corynebacterium glutamicum.
Gopinath V, Meiswinkel TM, Wendisch VF, Nampoothiri KM., Appl Microbiol Biotechnol 92(5), 2011
PMID: 21796382

64 References

Daten bereitgestellt von Europe PubMed Central.

Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product.
Duncan SH, Louis P, Flint HJ., Appl. Environ. Microbiol. 70(10), 2004
PMID: 15466518
D-lactate dehydrogenase of Desulfovibrio vulgaris.
Ogata M, Arihara K, Yagi T., J. Biochem. 89(5), 1981
PMID: 7275946
D-lactic acidosis: pathologic consequence of saprophytism.
Vella A, Farrugia G., Mayo Clin. Proc. 73(5), 1998
PMID: 9581587
The biosynthesis and functionality of the cell-wall of lactic acid bacteria.
Delcour J, Ferain T, Deghorain M, Palumbo E, Hols P., Antonie Van Leeuwenhoek 76(1-4), 1999
PMID: 10532377
Lactate racemization as a rescue pathway for supplying D-lactate to the cell wall biosynthesis machinery in Lactobacillus plantarum.
Goffin P, Deghorain M, Mainardi JL, Tytgat I, Champomier-Verges MC, Kleerebezem M, Hols P., J. Bacteriol. 187(19), 2005
PMID: 16166538
Scission of the lactyl ether bond of N-acetylmuramic acid by Escherichia coli "etherase".
Jaeger T, Arsic M, Mayer C., J. Biol. Chem. 280(34), 2005
PMID: 15983044
Transport of L-Lactate, D-Lactate, and glycolate by the LldP and GlcA membrane carriers of Escherichia coli.
Nunez MF, Kwon O, Wilson TH, Aguilar J, Baldoma L, Lin EC., Biochem. Biophys. Res. Commun. 290(2), 2002
PMID: 11785976
The L-lysine Story: From metabolic pathways to industrial production
AUTHOR UNKNOWN, 2007
Ethanol catabolism in Corynebacterium glutamicum.
Arndt A, Auchter M, Ishige T, Wendisch VF, Eikmanns BJ., J. Mol. Microbiol. Biotechnol. 15(4), 2007
PMID: 17693703
Genome-wide investigation of aromatic acid transporters in Corynebacterium glutamicum.
Chaudhry MT, Huang Y, Shen XH, Poetsch A, Jiang CY, Liu SJ., Microbiology (Reading, Engl.) 153(Pt 3), 2007
PMID: 17322206
Acetate metabolism and its regulation in Corynebacterium glutamicum.
Gerstmeir R, Wendisch VF, Schnicke S, Ruan H, Farwick M, Reinscheid D, Eikmanns BJ., J. Biotechnol. 104(1-3), 2003
PMID: 12948633
Vanillate metabolism in Corynebacterium glutamicum.
Merkens H, Beckers G, Wirtz A, Burkovski A., Curr. Microbiol. 51(1), 2005
PMID: 15971090
Characterization of citrate utilization in Corynebacterium glutamicum by transcriptome and proteome analysis.
Polen T, Schluesener D, Poetsch A, Bott M, Wendisch VF., FEMS Microbiol. Lett. 273(1), 2007
PMID: 17559405
Characterization of a Corynebacterium glutamicum lactate utilization operon induced during temperature-triggered glutamate production.
Stansen C, Uy D, Delaunay S, Eggeling L, Goergen JL, Wendisch VF., Appl. Environ. Microbiol. 71(10), 2005
PMID: 16204505
Structural and functional characterization of the LldR from Corynebacterium glutamicum: a transcriptional repressor involved in L-lactate and sugar utilization.
Gao YG, Suzuki H, Itou H, Zhou Y, Tanaka Y, Wachi M, Watanabe N, Tanaka I, Yao M., Nucleic Acids Res. 36(22), 2008
PMID: 18988622
Production of D-lactic acid by Corynebacterium glutamicum under oxygen deprivation.
Okino S, Suda M, Fujikura K, Inui M, Yukawa H., Appl. Microbiol. Biotechnol. 78(3), 2008
PMID: 18188553
Molecular Cloning
AUTHOR UNKNOWN, 1989
The lactic dehydrogenase of Propionibacterium pentosaceum.
MOLINARI R, LARA FJ., Biochem. J. 75(), 1960
PMID: 14423361
Studies on transformation of Escherichia coli with plasmids.
Hanahan D., J. Mol. Biol. 166(4), 1983
PMID: 6345791
Efficient electrotransformation of corynebacterium diphtheriae with a mini-replicon derived from the Corynebacterium glutamicum plasmid pGA1.
Tauch A, Kirchner O, Loffler B, Gotker S, Puhler A, Kalinowski J., Curr. Microbiol. 45(5), 2002
PMID: 12232668
Pyruvate carboxylase is a major bottleneck for glutamate and lysine production by Corynebacterium glutamicum.
Peters-Wendisch PG, Schiel B, Wendisch VF, Katsoulidis E, Mockel B, Sahm H, Eikmanns BJ., J. Mol. Microbiol. Biotechnol. 3(2), 2001
PMID: 11321586
The phosphate starvation stimulon of Corynebacterium glutamicum determined by DNA microarray analyses.
Ishige T, Krause M, Bott M, Wendisch VF, Sahm H., J. Bacteriol. 185(15), 2003
PMID: 12867461
Global expression profiling and physiological characterization of Corynebacterium glutamicum grown in the presence of L-valine.
Lange C, Rittmann D, Wendisch VF, Bott M, Sahm H., Appl. Environ. Microbiol. 69(5), 2003
PMID: 12732517
Genomewide expression analysis in amino acid-producing bacteria using DNA microarrays.
Polen T, Wendisch VF., Appl. Biochem. Biotechnol. 118(1-3), 2004
PMID: 15304751
The respiratory chain of Corynebacterium glutamicum.
Bott M, Niebisch A., J. Biotechnol. 104(1-3), 2003
PMID: 12948635
Corynebacterium efficiens sp. nov., a glutamic-acid-producing species from soil and vegetables.
Fudou R, Jojima Y, Seto A, Yamada K, Kimura E, Nakamatsu T, Hiraishi A, Yamanaka S., Int. J. Syst. Evol. Microbiol. 52(Pt 4), 2002
PMID: 12148616
Regulation of acetohydroxy acid synthase in Corynebacterium glutamicum during isoleucine formation from α-hydroxybutyric acid
AUTHOR UNKNOWN, 1987
The respiratory chain of Corynebacterium glutamicum.
Bott M, Niebisch A., J. Biotechnol. 104(1-3), 2003
PMID: 12948635
The crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzyme.
Dym O, Pratt EA, Ho C, Eisenberg D., Proc. Natl. Acad. Sci. U.S.A. 97(17), 2000
PMID: 10944213
Mapping the membrane proteome of Corynebacterium glutamicum.
Schluesener D, Fischer F, Kruip J, Rogner M, Poetsch A., Proteomics 5(5), 2005
PMID: 15717325
Dissimilatory pathways for sugars, polyols and carboxylates
AUTHOR UNKNOWN, 1996
Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R.
Yukawa H, Omumasaba CA, Nonaka H, Kos P, Okai N, Suzuki N, Suda M, Tsuge Y, Watanabe J, Ikeda Y, Vertes AA, Inui M., Microbiology (Reading, Engl.) 153(Pt 4), 2007
PMID: 17379713
The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.
Kalinowski J, Bathe B, Bartels D, Bischoff N, Bott M, Burkovski A, Dusch N, Eggeling L, Eikmanns BJ, Gaigalat L, Goesmann A, Hartmann M, Huthmacher K, Kramer R, Linke B, McHardy AC, Meyer F, Mockel B, Pfefferle W, Puhler A, Rey DA, Ruckert C, Rupp O, Sahm H, Wendisch VF, Wiegrabe I, Tauch A., J. Biotechnol. 104(1-3), 2003
PMID: 12948626
Microbial interactions in cheese: implications for cheese quality and safety.
Irlinger F, Mounier J., Curr. Opin. Biotechnol. 20(2), 2009
PMID: 19342218
Molecular analysis of human forearm superficial skin bacterial biota.
Gao Z, Tseng CH, Pei Z, Blaser MJ., Proc. Natl. Acad. Sci. U.S.A. 104(8), 2007
PMID: 17293459
A microbial factory for lactate-based polyesters using a lactate-polymerizing enzyme.
Taguchi S, Yamada M, Matsumoto K, Tajima K, Satoh Y, Munekata M, Ohno K, Kohda K, Shimamura T, Kambe H, Obata S., Proc. Natl. Acad. Sci. U.S.A. 105(45), 2008
PMID: 18978031
Genetically engineered wine yeast produces a high concentration of L-lactic acid of extremely high optical purity.
Saitoh S, Ishida N, Onishi T, Tokuhiro K, Nagamori E, Kitamoto K, Takahashi H., Appl. Environ. Microbiol. 71(5), 2005
PMID: 15870375
D-lactic acid production by metabolically engineered Saccharomyces cerevisiae.
Ishida N, Suzuki T, Tokuhiro K, Nagamori E, Onishi T, Saitoh S, Kitamoto K, Takahashi H., J. Biosci. Bioeng. 101(2), 2006
PMID: 16569615
Homofermentative production of D- or L-lactate in metabolically engineered Escherichia coli RR1.
Chang DE, Jung HC, Rhee JS, Pan JG., Appl. Environ. Microbiol. 65(4), 1999
PMID: 10103226
Production of optically pure D-lactic acid in mineral salts medium by metabolically engineered Escherichia coli W3110.
Zhou S, Causey TB, Hasona A, Shanmugam KT, Ingram LO., Appl. Environ. Microbiol. 69(1), 2003
PMID: 12514021
Conversion of aqueous ammonia-treated corn stover to lactic acid by simultaneous saccharification and cofermentation.
Zhu Y, Lee YY, Elander RT., Appl. Biochem. Biotechnol. 137-140(1-12), 2007
PMID: 18478429
Escherichia coli strains engineered for homofermentative production of D-lactic acid from glycerol.
Mazumdar S, Clomburg JM, Gonzalez R., Appl. Environ. Microbiol. 76(13), 2010
PMID: 20472739
Taxonomical studies on glutamic acid producing bacteria
AUTHOR UNKNOWN, 1967
PRODORIC: prokaryotic database of gene regulation.
Munch R, Hiller K, Barg H, Heldt D, Linz S, Wingender E, Jahn D., Nucleic Acids Res. 31(1), 2003
PMID: 12519998

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 21159175
PubMed | Europe PMC

Suchen in

Google Scholar