The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins

Kalinowski J, Bathe B, Bartels D, Bischoff N, Bott M, Burkovski A, Dusch N, Eggeling L, Eikmanns BJ, Gaigalat L, Goesmann A, et al. (2003)
Journal of Biotechnology 104(1-3): 5-25.

Journal Article | Published | English

No fulltext has been uploaded

Author
; ; ; ; ; ; ; ; ; ; ;
All
Abstract
The complete genomic sequence of Corynebacterium glutainicum ATCC 13032, well-known in industry for the production of amino acids, e.g. of L-glutamate and L-lysine was determined. The C glutamician genome was found to consist of a single circular chromosome comprising 3 282 708 base pairs. Several DNA regions of unusual composition were identified that were potentially acquired by horizontal gene transfer, e.g. a segment of DNA from C diphtheriae and a prophage-containing region. After automated and manual annotation, 3002 protein-coding genes have been identified, and to 2489 of these, functions were assigned by homologies to known proteins. These analyses confirm the taxonomic position of C glutamicum as related to Mycobacteria and show a broad metabolic diversity as expected for a bacterium living in the soil. As an example for biotechnological application the complete genome sequence was used to reconstruct the metabolic flow of carbon into a number of industrially important products derived from the amino acid L-aspartate. (C) 2003 Elsevier B.V. All rights reserved.
Publishing Year
ISSN
PUB-ID

Cite this

Kalinowski J, Bathe B, Bartels D, et al. The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. Journal of Biotechnology. 2003;104(1-3):5-25.
Kalinowski, J., Bathe, B., Bartels, D., Bischoff, N., Bott, M., Burkovski, A., Dusch, N., et al. (2003). The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. Journal of Biotechnology, 104(1-3), 5-25.
Kalinowski, J., Bathe, B., Bartels, D., Bischoff, N., Bott, M., Burkovski, A., Dusch, N., Eggeling, L., Eikmanns, B. J., Gaigalat, L., et al. (2003). The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. Journal of Biotechnology 104, 5-25.
Kalinowski, J., et al., 2003. The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. Journal of Biotechnology, 104(1-3), p 5-25.
J. Kalinowski, et al., “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins”, Journal of Biotechnology, vol. 104, 2003, pp. 5-25.
Kalinowski, J., Bathe, B., Bartels, D., Bischoff, N., Bott, M., Burkovski, A., Dusch, N., Eggeling, L., Eikmanns, B.J., Gaigalat, L., Goesmann, A., Hartmann, M., Huthmacher, K., Kramer, R., Linke, B., McHardy, A.C., Meyer, F., Mockel, B., Pfefferle, W., Pühler, A., Rey, D.A., Rückert, C., Rupp, O., Sahm, H., Wendisch, V.F., Wiegrabe, I., Tauch, A.: The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. Journal of Biotechnology. 104, 5-25 (2003).
Kalinowski, Jörn, Bathe, B., Bartels, D., Bischoff, N., Bott, M., Burkovski, A., Dusch, N., Eggeling, L., Eikmanns, B. J., Gaigalat, L., Goesmann, Alexander, Hartmann, M., Huthmacher, K., Kramer, R., Linke, Burkhard, McHardy, A. C., Meyer, F., Mockel, B., Pfefferle, W., Pühler, Alfred, Rey, D. A., Rückert, Christian, Rupp, O., Sahm, H., Wendisch, Volker F., Wiegrabe, I., and Tauch, Andreas. “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins”. Journal of Biotechnology 104.1-3 (2003): 5-25.
This data publication is cited in the following publications:
This publication cites the following data publications:

375 Citations in Europe PMC

Data provided by Europe PubMed Central.

Co-production of S-adenosyl-L-methionine and L-isoleucine in Corynebacterium glutamicum.
Han G, Hu X, Wang X., Enzyme Microb. Technol. 78(), 2015
PMID: 26215341
Identification of axillary Staphylococcus sp. involved in the production of the malodorous thioalcohol 3-methyl-3-sufanylhexan-1-ol.
Bawdon D, Cox DS, Ashford D, James AG, Thomas GH., FEMS Microbiol. Lett. 362(16), 2015
PMID: 26163522
Complete genome sequence of Corynebacterium glutamicum B253, a Chinese lysine-producing strain.
Wu Y, Li P, Zheng P, Zhou W, Chen N, Sun J., J. Biotechnol. 207(), 2015
PMID: 25953304
A prophage-encoded actin-like protein required for efficient viral DNA replication in bacteria.
Donovan C, Heyer A, Pfeifer E, Polen T, Wittmann A, Kramer R, Frunzke J, Bramkamp M., Nucleic Acids Res. 43(10), 2015
PMID: 25916847
The mannitol utilization system of the marine bacterium Zobellia galactanivorans.
Groisillier A, Labourel A, Michel G, Tonon T., Appl. Environ. Microbiol. 81(5), 2015
PMID: 25548051
Interaction between phage BFK20 helicase gp41 and its host Brevibacterium flavum primase DnaG.
Solteszova B, Halgasova N, Bukovska G., Virus Res. 196(), 2015
PMID: 25463056
Monitoring the enzyme expression in a respiratory chain of Corynebacterium glutamicum in a copper ion-supplemented culture medium.
Kusumoto T, Aoyagi M, Sugiyama T, Sakamoto J., Biosci. Biotechnol. Biochem. 79(2), 2015
PMID: 25338939
Metabolic engineering of Corynebacterium glutamicum strain ATCC13032 to produce L-methionine.
Qin T, Hu X, Hu J, Wang X., Biotechnol. Appl. Biochem. 62(4), 2015
PMID: 25196586
Efficient hydroxyproline production from glucose in minimal media by Corynebacterium glutamicum.
Falcioni F, Buhler B, Schmid A., Biotechnol. Bioeng. 112(2), 2015
PMID: 25163732
Improved production of poly(lactic acid)-like polyester based on metabolite analysis to address the rate-limiting step.
Matsumoto K, Tobitani K, Aoki S, Song Y, Ooi T, Taguchi S., AMB Express 4(1), 2014
PMID: 26267112
Analysis of cepA encoding an efflux pump-like protein in Corynebacterium glutamicum.
Sim SY, Hong EJ, Kim Y, Lee HS., J. Microbiol. 52(4), 2014
PMID: 24535744
Proteome response of Corynebacterium glutamicum to high concentration of industrially relevant C₄ and C₅ dicarboxylic acids.
Vasco-Cardenas MF, Banos S, Ramos A, Martin JF, Barreiro C., J Proteomics 85(), 2013
PMID: 23624027
Formation and metabolism of methylmalonyl coenzyme A in Corynebacterium glutamicum.
Botella L, Lindley ND, Eggeling L., J. Bacteriol. 191(8), 2009
PMID: 19233926
Crystallization and preliminary crystallographic analysis of cgHle, a homoserine acetyltransferase homologue, from Corynebacterium glutamicum.
Tolzer C, Pal S, Watzlawick H, Altenbuchner J, Niefind K., Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65(Pt 1), 2009
PMID: 19153452

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 12948626
PubMed | Europe PMC

Search this title in

Google Scholar