Transcriptional regulation of gene expression in Corynebacterium glutamicum: the role of global, master and local regulators in the modular and hierarchical gene regulatory network

Schröder J, Tauch A (2010)
FEMS Microbiology Reviews 34(5): 685-737.

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Zeitschriftenaufsatz | Veröffentlicht | Englisch
Abstract / Bemerkung
The genus Corynebacterium belongs to the taxonomic class Actinobacteria representing the high G+C branch of gram-positive bacteria. Among the most prominent members of this genus is Corynebacterium glutamicum, which is used by the biotechnological industry for the fermentative production of l-amino acids. Because of its industrial importance, C. glutamicum is one of the best-studied gram-positive bacteria and an emerging model for the suborder Corynebacterineae. Over the past years, the transcriptional regulation of gene expression was intensively studied in C. glutamicum to gain insights into the regulatory gene composition and the architecture of the transcriptional regulatory network. Therefore, we have achieved considerable improvements in understanding the regulatory roles of the various transcription regulators and the topology of the gene-regulatory network. This review summarizes the current knowledge of the regulatory gene repertoire and the reconstruction of the transcriptional regulatory network. We describe the functional classification of the detected transcription regulators and their interactions in the gene-regulatory network. Moreover, we provide an overview of the molecular features of transcription regulators and their regulons to integrate these data into the gene-regulatory network and to unravel the flow of information from the environment toward the gene level.
Erscheinungsjahr
Zeitschriftentitel
FEMS Microbiology Reviews
Band
34
Zeitschriftennummer
5
Seite
685-737
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eISSN
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Schröder J, Tauch A. Transcriptional regulation of gene expression in Corynebacterium glutamicum: the role of global, master and local regulators in the modular and hierarchical gene regulatory network. FEMS Microbiology Reviews. 2010;34(5):685-737.
Schröder, J., & Tauch, A. (2010). Transcriptional regulation of gene expression in Corynebacterium glutamicum: the role of global, master and local regulators in the modular and hierarchical gene regulatory network. FEMS Microbiology Reviews, 34(5), 685-737. doi:10.1111/j.1574-6976.2010.00228.x
Schröder, J., and Tauch, A. (2010). Transcriptional regulation of gene expression in Corynebacterium glutamicum: the role of global, master and local regulators in the modular and hierarchical gene regulatory network. FEMS Microbiology Reviews 34, 685-737.
Schröder, J., & Tauch, A., 2010. Transcriptional regulation of gene expression in Corynebacterium glutamicum: the role of global, master and local regulators in the modular and hierarchical gene regulatory network. FEMS Microbiology Reviews, 34(5), p 685-737.
J. Schröder and A. Tauch, “Transcriptional regulation of gene expression in Corynebacterium glutamicum: the role of global, master and local regulators in the modular and hierarchical gene regulatory network”, FEMS Microbiology Reviews, vol. 34, 2010, pp. 685-737.
Schröder, J., Tauch, A.: Transcriptional regulation of gene expression in Corynebacterium glutamicum: the role of global, master and local regulators in the modular and hierarchical gene regulatory network. FEMS Microbiology Reviews. 34, 685-737 (2010).
Schröder, Jasmin, and Tauch, Andreas. “Transcriptional regulation of gene expression in Corynebacterium glutamicum: the role of global, master and local regulators in the modular and hierarchical gene regulatory network”. FEMS Microbiology Reviews 34.5 (2010): 685-737.

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Jungwirth B, Sala C, Kohl TA, Uplekar S, Baumbach J, Cole ST, Pühler A, Tauch A., Microbiology 159(pt 1), 2013
PMID: 23103979
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Pátek M, Holátko J, Busche T, Kalinowski J, Nešvera J., Microb Biotechnol 6(2), 2013
PMID: 23305350
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PMID: 22803796
Construction of in vitro transcription system for Corynebacterium glutamicum and its use in the recognition of promoters of different classes.
Holátko J, Silar R, Rabatinová A, Sanderová H, Halada P, Nešvera J, Krásný L, Pátek M., Appl Microbiol Biotechnol 96(2), 2012
PMID: 22885668
Tools for genetic manipulations in Corynebacterium glutamicum and their applications.
Nešvera J, Pátek M., Appl Microbiol Biotechnol 90(5), 2011
PMID: 21519933
Comparative analysis of two complete Corynebacterium ulcerans genomes and detection of candidate virulence factors.
Trost E, Al-Dilaimi A, Papavasiliou P, Schneider J, Viehoever P, Burkovski A, Soares SC, Almeida SS, Dorella FA, Miyoshi A, Azevedo V, Schneider MP, Silva A, Santos CS, Santos LS, Sabbadini P, Dias AA, Hirata R, Mattos-Guaraldi AL, Tauch A., BMC Genomics 12(), 2011
PMID: 21801446
The complete genome sequence of Corynebacterium pseudotuberculosis FRC41 isolated from a 12-year-old girl with necrotizing lymphadenitis reveals insights into gene-regulatory networks contributing to virulence.
Trost E, Ott L, Schneider J, Schröder J, Jaenicke S, Goesmann A, Husemann P, Stoye J, Dorella FA, Rocha FS, Soares Sde C, D'Afonseca V, Miyoshi A, Ruiz J, Silva A, Azevedo V, Burkovski A, Guiso N, Join-Lambert OF, Kayal S, Tauch A., BMC Genomics 11(), 2010
PMID: 21192786

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