Adaptive servoventilation in diastolic heart failure and Cheyne-Stokes respiration

Bitter T, Westerheide N, Faber L, Hering D, Prinz C, Langer C, Horstkotte D, Oldenburg O (2010)
EUROPEAN RESPIRATORY JOURNAL 36(2): 385-392.

Download
No fulltext has been uploaded. References only!
Journal Article | Original Article | Published | English

No fulltext has been uploaded

Author
; ; ; ; ; ; ;
Abstract
A high prevalence of nocturnal Cheyne-Stokes respiration (CSR) has been documented in patients with heart failure with normal left ventricular ejection fraction (HFNEF). The aim of the present study was to investigate the effects of adaptive servoventilation (ASV) for treatment of CSR in these patients. In 60 patients with HFNEF, defined according to current European Society of Cardiology guidelines, CSR was documented by polysomnography (apnoea/hypopnoea index (AHI) of >15 events.h(-1)). ASV treatment was offered to all patients; 21 initially rejected treatment, withdrew from treatment or presented noncompliant during follow-up (controls), whereas ongoing ASV therapy was initiated in 39 patients (ASV group). Echocardiography, cardiopulmonary exercise testing and measurement of N-terminal-pro-brain natriuretic peptide were performed at baseline and follow-up (11.6 +/- 3 months). ASV therapy led to a significant reduction in AHI, longest apnoea and hypopnoea length, maximum and mean oxygen desaturation by pulse oximetry, percentage of study time with an oxygen saturation of <90% and arousal index. In addition, significant positive effects could be confirmed on absolute and predicted peak oxygen consumption, oxygen consumption at the individual aerobic-anaerobic threshold, oxygen pulse, as well as left atrial size, and transmitral flow patterns (mean early diastolic lengthening velocity and the ratio of peak early Doppler mitral inflow velocity to this lengthening velocity). ASV effectively attenuates CSR in patients with HFNEF and improves heart failure symptoms and cardiac function. Whether or not this is accompanied by an improved prognosis remains to be determined.
Publishing Year
ISSN
eISSN
PUB-ID

Cite this

Bitter T, Westerheide N, Faber L, et al. Adaptive servoventilation in diastolic heart failure and Cheyne-Stokes respiration. EUROPEAN RESPIRATORY JOURNAL. 2010;36(2):385-392.
Bitter, T., Westerheide, N., Faber, L., Hering, D., Prinz, C., Langer, C., Horstkotte, D., et al. (2010). Adaptive servoventilation in diastolic heart failure and Cheyne-Stokes respiration. EUROPEAN RESPIRATORY JOURNAL, 36(2), 385-392. doi:10.1183/09031936.00045609
Bitter, T., Westerheide, N., Faber, L., Hering, D., Prinz, C., Langer, C., Horstkotte, D., and Oldenburg, O. (2010). Adaptive servoventilation in diastolic heart failure and Cheyne-Stokes respiration. EUROPEAN RESPIRATORY JOURNAL 36, 385-392.
Bitter, T., et al., 2010. Adaptive servoventilation in diastolic heart failure and Cheyne-Stokes respiration. EUROPEAN RESPIRATORY JOURNAL, 36(2), p 385-392.
T. Bitter, et al., “Adaptive servoventilation in diastolic heart failure and Cheyne-Stokes respiration”, EUROPEAN RESPIRATORY JOURNAL, vol. 36, 2010, pp. 385-392.
Bitter, T., Westerheide, N., Faber, L., Hering, D., Prinz, C., Langer, C., Horstkotte, D., Oldenburg, O.: Adaptive servoventilation in diastolic heart failure and Cheyne-Stokes respiration. EUROPEAN RESPIRATORY JOURNAL. 36, 385-392 (2010).
Bitter, T., Westerheide, Nina, Faber, L., Hering, D., Prinz, C., Langer, C., Horstkotte, D., and Oldenburg, O. “Adaptive servoventilation in diastolic heart failure and Cheyne-Stokes respiration”. EUROPEAN RESPIRATORY JOURNAL 36.2 (2010): 385-392.
This data publication is cited in the following publications:
This publication cites the following data publications:

38 Citations in Europe PMC

Data provided by Europe PubMed Central.

Biomarkers in Sleep Apnea and Heart Failure.
Zhao YY, Mehra R., Curr Heart Fail Rep 14(4), 2017
PMID: 28667490
Sleep-Disordered Breathing and Arrhythmia in Heart Failure Patients.
Fox H, Bitter T, Horstkotte D, Oldenburg O., Sleep Med Clin 12(2), 2017
PMID: 28477777
Whom are we treating with adaptive servo-ventilation? A clinical post hoc analysis.
Malfertheiner MV, Lerzer C, Kolb L, Heider K, Zeman F, Gfullner F, Maier LS, Pfeifer M, Arzt M., Clin Res Cardiol 106(9), 2017
PMID: 28417254
Management of Sleep Apnea Syndromes in Heart Failure.
Selim BJ, Ramar K., Sleep Med Clin 12(1), 2017
PMID: 28159090
Noninvasive ventilation improves cardiac function in patients with chronic heart failure.
Cheng J, Liu Y, Li G, Zhang Z, Ma L, Yang X, Yang J, Zhang K, Kong J, Dong M, Zhang M, Xu X, Sui W, Wang J, Shang R, Ji X, Zhang Y, Zhang C, Hao P., Oncotarget 7(31), 2016
PMID: 27391436
Sleep-disordered Breathing in Heart Failure - Current State of the Art.
Cowie MR, Woehrle H, Oldenburg O, Damy T, van der Meer P, Erdman E, Metra M, Zannad F, Trochu JN, Gullestad L, Fu M, Bohm M, Auricchio A, Levy P., Card Fail Rev 1(1), 2015
PMID: 28785426
Acute hemodynamic effects of adaptive servoventilation in patients with pre-capillary and post-capillary pulmonary hypertension.
Olsson KM, Frank A, Fuge J, Welte T, Hoeper MM, Bitter T., Respir. Res. 16(), 2015
PMID: 26538143
Nocturnal non-invasive ventilation for cardio-respiratory disorders in adults.
Wahab R, Basner RC., Expert Rev Respir Med 7(6), 2013
PMID: 24175738

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 20032021
PubMed | Europe PMC

Search this title in

Google Scholar