Single-molecule force spectroscopy of supramolecular heterodimeric capsules

Schröder T, Geisler T, Walhorn V, Schnatwinkel B, Anselmetti D, Mattay J (2010)
Physical Chemistry Chemical Physics 12(36): 10981-10987.

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Abstract
The specific interaction of a supramolecular binding motif was quantitatively evaluated by dynamic single-molecule force spectroscopy (SMFS) using an atomic force microscope (AFM). The supramolecular capsule forms by two different cavitands stitched together by four hydrogen bonds between carboxylic acid and pyridyl groups. The tetra(carboxyl) cavitand is monofunctionalized at the lower rim with a flexible poly(ethylene glycol) linker and attached to the AFM sensor tip. Single-molecule association experiments are accomplished using a diluted self-assembled monolayer (SAM) of the tetra(pyridyl) cavitand on a gold substrate. The measured single-molecule dissociation forces of the heterodimeric capsule represent the mechanical stability of the supramolecular system and allow a quantitative evaluation of the interaction according to the Bell-Evans model yielding dissociation rate constant k(off) = (0.14 +/- 0.14) s(-1), reaction length x(beta) = (0.56 +/- 0.076) nm and an estimated value of Delta G(0) = -27 kJ mol(-1).
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Schröder T, Geisler T, Walhorn V, Schnatwinkel B, Anselmetti D, Mattay J. Single-molecule force spectroscopy of supramolecular heterodimeric capsules. Physical Chemistry Chemical Physics. 2010;12(36):10981-10987.
Schröder, T., Geisler, T., Walhorn, V., Schnatwinkel, B., Anselmetti, D., & Mattay, J. (2010). Single-molecule force spectroscopy of supramolecular heterodimeric capsules. Physical Chemistry Chemical Physics, 12(36), 10981-10987.
Schröder, T., Geisler, T., Walhorn, V., Schnatwinkel, B., Anselmetti, D., and Mattay, J. (2010). Single-molecule force spectroscopy of supramolecular heterodimeric capsules. Physical Chemistry Chemical Physics 12, 10981-10987.
Schröder, T., et al., 2010. Single-molecule force spectroscopy of supramolecular heterodimeric capsules. Physical Chemistry Chemical Physics, 12(36), p 10981-10987.
T. Schröder, et al., “Single-molecule force spectroscopy of supramolecular heterodimeric capsules”, Physical Chemistry Chemical Physics, vol. 12, 2010, pp. 10981-10987.
Schröder, T., Geisler, T., Walhorn, V., Schnatwinkel, B., Anselmetti, D., Mattay, J.: Single-molecule force spectroscopy of supramolecular heterodimeric capsules. Physical Chemistry Chemical Physics. 12, 10981-10987 (2010).
Schröder, Tobias, Geisler, Thomas, Walhorn, Volker, Schnatwinkel, Bjoern, Anselmetti, Dario, and Mattay, Jochen. “Single-molecule force spectroscopy of supramolecular heterodimeric capsules”. Physical Chemistry Chemical Physics 12.36 (2010): 10981-10987.
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Data provided by Europe PubMed Central.

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PMID: 25863062
Molecular modeling of enzyme attachment on AFM probes.
Oliveira GS, Leite FL, Amarante AM, Franca EF, Cunha RA, Briggs JM, Freitas LC., J. Mol. Graph. Model. 45(), 2013
PMID: 24029365
Hidden multiple bond effects in dynamic force spectroscopy.
Getfert S, Reimann P., Biophys. J. 102(5), 2012
PMID: 22404941
Mechanical control of nanomaterials and nanosystems.
Ariga K, Mori T, Hill JP., Adv. Mater. Weinheim 24(2), 2012
PMID: 21953700
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PMID: 22009325
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92 References

Data provided by Europe PubMed Central.

Single-molecule experiments to elucidate the minimal requirement for DNA recognition by transcription factor epitopes.
Wollschlager K, Gaus K, Kornig A, Eckel R, Wilking SD, McIntosh M, Majer Z, Becker A, Ros R, Anselmetti D, Sewald N., Small 5(4), 2009
PMID: 19199332
Mechanically interlocked calix[4]arene dimers display reversible bond breakage under force.
Janke M, Rudzevich Y, Molokanova O, Metzroth T, Mey I, Diezemann G, Marszalek PE, Gauss J, Bohmer V, Janshoff A., Nat Nanotechnol 4(4), 2009
PMID: 19350031
Light powered molecular machines.
Balzani V, Credi A, Venturi M., Chem Soc Rev 38(6), 2009
PMID: 19587950
A molecular force probe.
Yang QZ, Huang Z, Kucharski TJ, Khvostichenko D, Chen J, Boulatov R., Nat Nanotechnol 4(5), 2009
PMID: 19421215
Interconversion between molecular polyhedra and metal-organic frameworks.
Li JR, Timmons DJ, Zhou HC., J. Am. Chem. Soc. 131(18), 2009
PMID: 19374418
First principles dynamics and minimum energy pathways for mechanochemical ring opening of cyclobutene.
Ong MT, Leiding J, Tao H, Virshup AM, Martinez TJ., J. Am. Chem. Soc. 131(18), 2009
PMID: 19378993
Functional Molecular Flasks: New Properties and Reactions within Discrete, Self-Assembled Hosts
Yoshizawa, Angewandte Chemie International Edition 48(19), 2009
Metal-organic macrocycles, metal-organic polyhedra and metal-organic frameworks.
Prakash MJ, Lah MS., Chem. Commun. (Camb.) (23), 2009
PMID: 19503863
Understanding Covalent Mechanochemistry
Ribas-Arino, Angewandte Chemie International Edition 48(23), 2009
Binding Mechanisms in Supramolecular Complexes
Schneider, Angewandte Chemie International Edition 48(22), 2009
Self-organization in coordination-driven self-assembly.
Northrop BH, Zheng YR, Chi KW, Stang PJ., Acc. Chem. Res. 42(10), 2009
PMID: 19555073
Constitutional Adaptation of Dynamic Polymers: Hydrophobically Driven Sequence Selection in Dynamic Covalent Polyacylhydrazones
Folmer-Andersen, Angewandte Chemie International Edition 48(41), 2009
Multiresponsive supramolecular nanogated ensembles.
Liu R, Zhang Y, Feng P., J. Am. Chem. Soc. 131(42), 2009
PMID: 19746981
White phosphorus is air-stable within a self-assembled tetrahedral capsule.
Mal P, Breiner B, Rissanen K, Nitschke JR., Science 324(5935), 2009
PMID: 19556504
High-symmetry coordination cages via self-assembly.
Seidel SR, Stang PJ., Acc. Chem. Res. 35(11), 2002
PMID: 12437322

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