Prevalence and risk factors of syphilis infection among drug addicts

Scherbaum N, Baune BT, Mikolajczyk RT, Kuhlmann T, Reymann G, Reker M (2005)
BMC Infectious Diseases 5(1).

Download
OA
Journal Article | Published | English
Author
; ; ; ; ;
Abstract
Background: Recent epidemiological data show an increased trend of official estimates for syphilis infection in the general population. Many of the infected cases remain undetected leaving an underestimation of the true prevalence of syphilis in the general population, but also among subpopulations such as illicit drug users. There is limited epidemiological data published on the proportion and risk factors of syphilis infections associated with illicit drug abuse. Methods: Illicit drug addicts (n = 1223) in inpatients units in Germany were screened (2000-01) for syphilis and interviewed regarding patterns of drug use and sexual behaviour. TPHA-test for initial screening and FTA-ABS-IgM test in TPHA-positive patients were used. Results: In total, TPHA-tests were positive in 39 (3.3%) and 7 patients (0.6%) were IgM positive. The prevalence rate for syphilis in males was 1.9% and for women it was 8.5%. Female patients were 4.56 (CI 95% 2.37-8.78) times more likely to have a positive TPHA test than males. Sexual behaviours such as high number of sexual partners, sex for drugs/money, sex on the first day were associated with syphilis infection only in women. Females with frequent sex for drugs or money had 4.31 (CI 95% 2.32-8.52) times more likely a reactive TPHA test than remaining patients. Neither the sociodemographic factors nor sexual behaviour were statistically significant associated with syphilis infection among men at all. Conclusion: Our data suggest the need for screening for syphilis among these illicit drug users in inpatient settings, in particular among sexual active women. This conclusion is corroborated by the finding of increasing numbers of syphilis infections in the general population. The identification of syphilis cases among drug addicts would give treatment options to these individuals and would help to reduce the spread of infection in this population, but also a spread into heterosexual populations related to prostitution.
Publishing Year
ISSN
PUB-ID

Cite this

Scherbaum N, Baune BT, Mikolajczyk RT, Kuhlmann T, Reymann G, Reker M. Prevalence and risk factors of syphilis infection among drug addicts. BMC Infectious Diseases. 2005;5(1).
Scherbaum, N., Baune, B. T., Mikolajczyk, R. T., Kuhlmann, T., Reymann, G., & Reker, M. (2005). Prevalence and risk factors of syphilis infection among drug addicts. BMC Infectious Diseases, 5(1).
Scherbaum, N., Baune, B. T., Mikolajczyk, R. T., Kuhlmann, T., Reymann, G., and Reker, M. (2005). Prevalence and risk factors of syphilis infection among drug addicts. BMC Infectious Diseases 5.
Scherbaum, N., et al., 2005. Prevalence and risk factors of syphilis infection among drug addicts. BMC Infectious Diseases, 5(1).
N. Scherbaum, et al., “Prevalence and risk factors of syphilis infection among drug addicts”, BMC Infectious Diseases, vol. 5, 2005.
Scherbaum, N., Baune, B.T., Mikolajczyk, R.T., Kuhlmann, T., Reymann, G., Reker, M.: Prevalence and risk factors of syphilis infection among drug addicts. BMC Infectious Diseases. 5, (2005).
Scherbaum, Norbert, Baune, Bernhard T., Mikolajczyk, Rafael T., Kuhlmann, Thomas, Reymann, Gerhard, and Reker, Martin. “Prevalence and risk factors of syphilis infection among drug addicts”. BMC Infectious Diseases 5.1 (2005).
Main File(s)
Access Level
OA Open Access

This data publication is cited in the following publications:
This publication cites the following data publications:

2 Citations in Europe PMC

Data provided by Europe PubMed Central.

Seroprevalence of certain bacterial and viral infections among the Irula tribal population of Marakkanam, Tamil Nadu state, India.
Gnanasekaran A, Paramasivam R, Mohan K, Daniel JC, Murugasan K, Perumal Kannabiran U, Selvaraj S, Chockalingam M, Moorthy S, Melani R, Nivedha R., Prim Health Care Res Dev 14(2), 2013
PMID: 23174132
Managing congenital syphilis again? The more things change ...
Chakraborty R, Luck S., Curr. Opin. Infect. Dis. 20(3), 2007
PMID: 17471033

20 References

Data provided by Europe PubMed Central.

Prevalence of HIV, syphilis and genital chlamydial infection among women in north-west Ethiopia.
Aseffa A, Ishak A, Stevens R, Fergussen E, Giles M, Yohannes G, Kidan KG., Epidemiol. Infect. 120(2), 1998
PMID: 9593487
Syphilis in Murewa District, Zimbabwe: an old problem that rages on.
Kambarami RA, Manyame B, Macq J., Cent Afr J Med 44(9), 1998
PMID: 10101428
[The epidemiology of neurosyphilis (author's transl)]
Prange H, Ritter G., Nervenarzt 52(1), 1981
PMID: 7219611
[Current data and information on infectious diseases: current implications]
AUTHOR UNKNOWN, 1997
[Current data and information on infectious diseases and Public Health: Syphilis in Germany in 2002]
AUTHOR UNKNOWN, 2003
A prospective study of syphilis and HIV infection among injection drug users receiving methadone in the Bronx, NY.
Gourevitch MN, Hartel D, Schoenbaum EE, Selwyn PA, Davenny K, Friedland GH, Klein RS., Am J Public Health 86(8), 1996
PMID: 8712270
[Cost-effectiveness of syphilis screening in a clinical for general psychiatry]
Banger M, Olbrich HM, Fuchs S, Gastpar M., Nervenarzt 66(1), 1995
PMID: 7885513
[Economic aspects of serologic syphilis tests in routine screening in Viennese hospital facilities]
Luger A, Gschnait F, Niebauer G., Wien. Klin. Wochenschr. 99(23), 1987
PMID: 3124355
Infectious disease working group of the German Society of Urology: Guidelines for the diagnostic and treatment of STDs
Schneede P, Hofstetter A., 0
Guidelines Revision Group. UK national guidelines on the management of late syphilis 2002
French P, Syphilis ., 0
Sensitivity and specificity of TPHA test
Egglestone St, Ashley I., 1995
SPSS for Windows, Release 11.01
AUTHOR UNKNOWN, 0
Prevalence of sexually transmitted infections and associated risk factors among populations of drug abusers.
Hwang LY, Ross MW, Zack C, Bull L, Rickman K, Holleman M., Clin. Infect. Dis. 31(4), 2000
PMID: 11049771
Syphilis in injecting drug users: clues for high-risk sexual behaviour in female IDUs.
Muga R, Roca J, Tor J, Pigem C, Rodriguez R, Egea JM, Vlahov D, Munoz A., Int J STD AIDS 8(4), 1997
PMID: 9147154
Injecting drug users in Bangladesh: prevalence of syphilis, hepatitis, HIV and HIV subtypes.
Azim T, Bogaerts J, Yirrell DL, Banerjea AC, Sarker MS, Ahmed G, Amin MM, Rahman AS, Hussain AM., AIDS 16(1), 2002
PMID: 11741170
Social change and HIV in the former USSR: the making of a new epidemic.
Atlani L, Carael M, Brunet JB, Frasca T, Chaika N., Soc Sci Med 50(11), 2000
PMID: 10795962
Risk factors for syphilis: cocaine use and prostitution.
Rolfs RT, Goldberg M, Sharrar RG., Am J Public Health 80(7), 1990
PMID: 2356911
No positive tests for syphilis in 6 years of observation among heroin drug users in north-eastern Italy.
Lugoboni F, Quaglio G, Mezzelani P, Lechi A., Addiction 97(1), 2002
PMID: 11895263

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 15904501
PubMed | Europe PMC

Search this title in

Google Scholar