Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications

Ros R, Eckel R, Bartels FW, Sischka A, Baumgarth B, Wilking SD, Pühler A, Sewald N, Becker A, Anselmetti D (2004)
Journal of Biotechnology 112(1-2): 5-12.

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Abstract
Recent developments in single molecule force spectroscopy (SMFS) allow direct observation and measurements of forces that hold protein-DNA complexes together. Furthermore, the mechanics of double-stranded (ds) DNA molecules in the presence of small binding ligands can be detected. The results elucidate molecular binding mechanisms and open the way for ultra sensitive and powerful biosensor applications.
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Ros R, Eckel R, Bartels FW, et al. Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. Journal of Biotechnology. 2004;112(1-2):5-12.
Ros, R., Eckel, R., Bartels, F. W., Sischka, A., Baumgarth, B., Wilking, S. D., Pühler, A., et al. (2004). Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. Journal of Biotechnology, 112(1-2), 5-12. doi:10.1016/j.jbiotec.2004.04.029
Ros, R., Eckel, R., Bartels, F. W., Sischka, A., Baumgarth, B., Wilking, S. D., Pühler, A., Sewald, N., Becker, A., and Anselmetti, D. (2004). Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. Journal of Biotechnology 112, 5-12.
Ros, R., et al., 2004. Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. Journal of Biotechnology, 112(1-2), p 5-12.
R. Ros, et al., “Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications”, Journal of Biotechnology, vol. 112, 2004, pp. 5-12.
Ros, R., Eckel, R., Bartels, F.W., Sischka, A., Baumgarth, B., Wilking, S.D., Pühler, A., Sewald, N., Becker, A., Anselmetti, D.: Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications. Journal of Biotechnology. 112, 5-12 (2004).
Ros, Robert, Eckel, Rainer, Bartels, Frank Wilco, Sischka, Andy, Baumgarth, Birgit, Wilking, Sven David, Pühler, Alfred, Sewald, Norbert, Becker, Anke, and Anselmetti, Dario. “Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications”. Journal of Biotechnology 112.1-2 (2004): 5-12.
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