Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions

Stoye J, Evers D, Meyer F (1997)
In: Proc. of ISMB 1997. 303-306.

Conference Paper | Published | English

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Abstract
We present a new probabilistic model of evolution of RNA-, DNA-, or protein-like sequences and a tool rose that implements this model. By insertion, deletion and substitution of characters, a family of sequences is created from a common ancestor. During this artificial evolutionary process, the "true" history is logged and the "correct" multiple sequence alignment is created simultaneously. We also allow for varying rates of mutation within the sequences making it possible to establish so-called sequence motifs. The results are suitable for the evaluation of methods in multiple sequence alignment computation and the prediction of phylogenetic relationships.
Publishing Year
Conference
ISMB 1997
Location
Halkidiki, Greece
ISSN
PUB-ID

Cite this

Stoye J, Evers D, Meyer F. Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions. In: Proc. of ISMB 1997. 1997: 303-306.
Stoye, J., Evers, D., & Meyer, F. (1997). Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions. Proc. of ISMB 1997, 303-306.
Stoye, J., Evers, D., and Meyer, F. (1997). “Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions” in Proc. of ISMB 1997 303-306.
Stoye, J., Evers, D., & Meyer, F., 1997. Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions. In Proc. of ISMB 1997. pp. 303-306.
J. Stoye, D. Evers, and F. Meyer, “Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions”, Proc. of ISMB 1997, 1997, pp.303-306.
Stoye, J., Evers, D., Meyer, F.: Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions. Proc. of ISMB 1997. p. 303-306. (1997).
Stoye, Jens, Evers, Dirk, and Meyer, Folker. “Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions”. Proc. of ISMB 1997. 1997. 303-306.
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