Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions

Stoye J, Evers D, Meyer F (1997)
In: Proc. of ISMB 1997. 303-306.

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Konferenzbeitrag | Veröffentlicht | Englisch
Autor
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Abstract / Bemerkung
We present a new probabilistic model of evolution of RNA-, DNA-, or protein-like sequences and a tool rose that implements this model. By insertion, deletion and substitution of characters, a family of sequences is created from a common ancestor. During this artificial evolutionary process, the "true" history is logged and the "correct" multiple sequence alignment is created simultaneously. We also allow for varying rates of mutation within the sequences making it possible to establish so-called sequence motifs. The results are suitable for the evaluation of methods in multiple sequence alignment computation and the prediction of phylogenetic relationships.
Erscheinungsjahr
Titel des Konferenzbandes
Proc. of ISMB 1997
Seite
303-306
Konferenz
ISMB 1997
Konferenzort
Halkidiki, Greece
ISSN
PUB-ID

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Stoye J, Evers D, Meyer F. Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions. In: Proc. of ISMB 1997. 1997: 303-306.
Stoye, J., Evers, D., & Meyer, F. (1997). Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions. Proc. of ISMB 1997, 303-306.
Stoye, J., Evers, D., and Meyer, F. (1997). “Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions” in Proc. of ISMB 1997 303-306.
Stoye, J., Evers, D., & Meyer, F., 1997. Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions. In Proc. of ISMB 1997. pp. 303-306.
J. Stoye, D. Evers, and F. Meyer, “Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions”, Proc. of ISMB 1997, 1997, pp.303-306.
Stoye, J., Evers, D., Meyer, F.: Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions. Proc. of ISMB 1997. p. 303-306. (1997).
Stoye, Jens, Evers, Dirk, and Meyer, Folker. “Generating benchmarks for multiple sequence alignments and phylogenetic reconstructions”. Proc. of ISMB 1997. 1997. 303-306.

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