DIFFERENTIAL SYNTHESIS BY CULTURED ATRIAL AND VENTRICULAR RAT CARDIAC MYOCYTES OF MYOSIN LIGHT CHAIN ISOFORMS

BRAND T, MILTING H, ZIPPEL M, Jockusch H (1991)
FEBS LETTERS 283(2): 289-290.

Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Autor
; ; ;
Abstract / Bemerkung
Dissociated cells from neonatal rat atria and ventricles were cultured in monolayers for 3 days. Newly synthesized S-35-methionine labeled myosin light chain isoforms ALC-1 ALC-2 (atrial) and VLC-1, VLC-2 (ventricular) were identified on 2D gels, and their pattern of synthesis was compared to that of myocard fragments immediately after explanatation. ALCs were synthesized in 5- to 10-fold excess over VLCs by atrial cultures, whereas the converse was true for ventricular cultures, with two exceptions: one third of the LC-1 synthesized by ventricular fragments was ALC-1, and dissociated atrial cells synthesized very little LC-2 of either isoform. The former finding corresponds to the relatively high proportion of ALC-1 in neonatal ventricular tissue. We conclude that the regional programme of LC isoform expression is basically retained after tissue explanation and even after dissociation and culturing of cardiac myocytes.
Erscheinungsjahr
Zeitschriftentitel
FEBS LETTERS
Band
283
Zeitschriftennummer
2
Seite
289-290
ISSN
PUB-ID

Zitieren

BRAND T, MILTING H, ZIPPEL M, Jockusch H. DIFFERENTIAL SYNTHESIS BY CULTURED ATRIAL AND VENTRICULAR RAT CARDIAC MYOCYTES OF MYOSIN LIGHT CHAIN ISOFORMS. FEBS LETTERS. 1991;283(2):289-290.
BRAND, T., MILTING, H., ZIPPEL, M., & Jockusch, H. (1991). DIFFERENTIAL SYNTHESIS BY CULTURED ATRIAL AND VENTRICULAR RAT CARDIAC MYOCYTES OF MYOSIN LIGHT CHAIN ISOFORMS. FEBS LETTERS, 283(2), 289-290. doi:10.1016/0014-5793(91)80610-F
BRAND, T., MILTING, H., ZIPPEL, M., and Jockusch, H. (1991). DIFFERENTIAL SYNTHESIS BY CULTURED ATRIAL AND VENTRICULAR RAT CARDIAC MYOCYTES OF MYOSIN LIGHT CHAIN ISOFORMS. FEBS LETTERS 283, 289-290.
BRAND, T., et al., 1991. DIFFERENTIAL SYNTHESIS BY CULTURED ATRIAL AND VENTRICULAR RAT CARDIAC MYOCYTES OF MYOSIN LIGHT CHAIN ISOFORMS. FEBS LETTERS, 283(2), p 289-290.
T. BRAND, et al., “DIFFERENTIAL SYNTHESIS BY CULTURED ATRIAL AND VENTRICULAR RAT CARDIAC MYOCYTES OF MYOSIN LIGHT CHAIN ISOFORMS”, FEBS LETTERS, vol. 283, 1991, pp. 289-290.
BRAND, T., MILTING, H., ZIPPEL, M., Jockusch, H.: DIFFERENTIAL SYNTHESIS BY CULTURED ATRIAL AND VENTRICULAR RAT CARDIAC MYOCYTES OF MYOSIN LIGHT CHAIN ISOFORMS. FEBS LETTERS. 283, 289-290 (1991).
BRAND, T, MILTING, H, ZIPPEL, M, and Jockusch, Harald. “DIFFERENTIAL SYNTHESIS BY CULTURED ATRIAL AND VENTRICULAR RAT CARDIAC MYOCYTES OF MYOSIN LIGHT CHAIN ISOFORMS”. FEBS LETTERS 283.2 (1991): 289-290.

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 2044768
PubMed | Europe PMC

Suchen in

Google Scholar