DIFFERENT BINDING-CAPACITIES OF INFLUENZA-A AND SENDAI VIRUSES TO GANGLIOSIDES FROM HUMAN GRANULOCYTES

Müthing J, UNLAND F, HEITMANN D, ORLICH M, HANISCH FG, PETERKATALINIC J, KNAUPER V, Tschesche H, KELM S, SCHAUER R, LEHMANN J (1993)
GLYCOCONJUGATE JOURNAL 10(1): 120-126.

Journal Article | Published | English

No fulltext has been uploaded

Author
; ; ; ; ; ; ; ; ; ;
Abstract
The structures of gangliosides from human granulocytes were elucidated by fast atom bombardment mass spectrometry and by gas chromatography/mass spectrometry as their partially methylated alditol acetates. In human granulocytes besides G(M3) (II3Neu5Ac-LacCer), neolacto-series gangliosides (IV3Neu5Ac-nLcOse4Cer, IV6Neu5Ac-nLcOse4Cer and VI3Neu5Ac-nLcOse6Cer) containing C24:1, and to some extent C22:0; and C-16:0 fatty acid in their respective ceramide portions, were identified as major components. In this study we demonstrate that gangliosides from human granulocytes, the second most abundant cells in peripheral blood, can serve as receptors for influenza viruses A/PR/8/34 (H1N1), A/X-31 (H3N2), and a parainfluenza virus Sendai virus (HNF1, Z-strain). Viruses were found to exhibit specific adhesion to terminal Neu5Acalpha2-3Gal and/or Neu5Acalpha2-6Gal sequences as well as depending on the chain length of ganglioside carbohydrate backbones from human granulocytes, these important effector cells which represent the first line of defence in immunologically mediated reactions.
Publishing Year
ISSN
eISSN
PUB-ID

Cite this

Müthing J, UNLAND F, HEITMANN D, et al. DIFFERENT BINDING-CAPACITIES OF INFLUENZA-A AND SENDAI VIRUSES TO GANGLIOSIDES FROM HUMAN GRANULOCYTES. GLYCOCONJUGATE JOURNAL. 1993;10(1):120-126.
Müthing, J., UNLAND, F., HEITMANN, D., ORLICH, M., HANISCH, F. G., PETERKATALINIC, J., KNAUPER, V., et al. (1993). DIFFERENT BINDING-CAPACITIES OF INFLUENZA-A AND SENDAI VIRUSES TO GANGLIOSIDES FROM HUMAN GRANULOCYTES. GLYCOCONJUGATE JOURNAL, 10(1), 120-126.
Müthing, J., UNLAND, F., HEITMANN, D., ORLICH, M., HANISCH, F. G., PETERKATALINIC, J., KNAUPER, V., Tschesche, H., KELM, S., SCHAUER, R., et al. (1993). DIFFERENT BINDING-CAPACITIES OF INFLUENZA-A AND SENDAI VIRUSES TO GANGLIOSIDES FROM HUMAN GRANULOCYTES. GLYCOCONJUGATE JOURNAL 10, 120-126.
Müthing, J., et al., 1993. DIFFERENT BINDING-CAPACITIES OF INFLUENZA-A AND SENDAI VIRUSES TO GANGLIOSIDES FROM HUMAN GRANULOCYTES. GLYCOCONJUGATE JOURNAL, 10(1), p 120-126.
J. Müthing, et al., “DIFFERENT BINDING-CAPACITIES OF INFLUENZA-A AND SENDAI VIRUSES TO GANGLIOSIDES FROM HUMAN GRANULOCYTES”, GLYCOCONJUGATE JOURNAL, vol. 10, 1993, pp. 120-126.
Müthing, J., UNLAND, F., HEITMANN, D., ORLICH, M., HANISCH, F.G., PETERKATALINIC, J., KNAUPER, V., Tschesche, H., KELM, S., SCHAUER, R., LEHMANN, J.: DIFFERENT BINDING-CAPACITIES OF INFLUENZA-A AND SENDAI VIRUSES TO GANGLIOSIDES FROM HUMAN GRANULOCYTES. GLYCOCONJUGATE JOURNAL. 10, 120-126 (1993).
Müthing, Johannes, UNLAND, F, HEITMANN, D, ORLICH, M, HANISCH, FG, PETERKATALINIC, J, KNAUPER, V, Tschesche, Harald, KELM, S, SCHAUER, R, and LEHMANN, J. “DIFFERENT BINDING-CAPACITIES OF INFLUENZA-A AND SENDAI VIRUSES TO GANGLIOSIDES FROM HUMAN GRANULOCYTES”. GLYCOCONJUGATE JOURNAL 10.1 (1993): 120-126.
This data publication is cited in the following publications:
This publication cites the following data publications:

17 Citations in Europe PMC

Data provided by Europe PubMed Central.

On-line nano-HPLC/ESI QTOF MS monitoring of alpha2-3 and alpha2-6 sialylation in granulocyte glycosphingolipidome.
Kirsch S, Muthing J, Peter-Katalinic J, Bindila L., Biol. Chem. 390(7), 2009
PMID: 19361287
Glycosphingolipids in vascular endothelial cells: relationship of heterogeneity in Gb3Cer/CD77 receptor expression with differential Shiga toxin 1 cytotoxicity.
Schweppe CH, Bielaszewska M, Pohlentz G, Friedrich AW, Buntemeyer H, Schmidt MA, Kim KS, Peter-Katalinic J, Karch H, Muthing J., Glycoconj. J. 25(4), 2008
PMID: 18176841
Oxygenation alters ganglioside expression in rat liver following partial hepatectomy.
Markotic A, Culic VC, Kurir TT, Meisen I, Buntemeyer H, Boraska V, Zemunik T, Petri N, Mesaric M, Peter-Katalinic J, Muthing J., Biochem. Biophys. Res. Commun. 330(1), 2005
PMID: 15781242
Preferential binding of the anticancer drug rViscumin (recombinant mistletoe lectin) to terminally alpha2-6-sialylated neolacto-series gangliosides.
Muthing J, Burg M, Mockel B, Langer M, Metelmann-Strupat W, Werner A, Neumann U, Peter-Katalinic J, Eck J., Glycobiology 12(8), 2002
PMID: 12145189
Ganglioside expression in tissues of mice lacking beta2-microglobulin.
Markotic A, Marusic A, Tomac J, Muthing J., Clin. Exp. Immunol. 128(1), 2002
PMID: 11982587
Anencephaly: structural characterization of gangliosides in defined brain regions.
Vukelic Z, Metelmann W, Muthing J, Kos M, Peter-Katalinic J., Biol. Chem. 382(2), 2001
PMID: 11308024
A strain of human influenza A virus binds to extended but not short gangliosides as assayed by thin-layer chromatography overlay.
Miller-Podraza H, Johansson L, Johansson P, Larsson T, Matrosovich M, Karlsson KA., Glycobiology 10(10), 2000
PMID: 11030743
Ganglioside expression in tissues of mice lacking the tumor necrosis factor receptor 1.
Markotic A, Lumen R, Marusic A, Jonjic S, Muthing J., Carbohydr. Res. 321(1-2), 1999
PMID: 10612003
High-resolution thin-layer chromatography of gangliosides.
Muthing J., J Chromatogr A 720(1-2), 1996
PMID: 8601198

26 References

Data provided by Europe PubMed Central.


G, Glycoconjugate J 5(), 1988

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 8395268
PubMed | Europe PMC

Search this title in

Google Scholar