DIRECT ACTIVATION OF HUMAN NEUTROPHIL PROCOLLAGENASE BY RECOMBINANT STROMELYSIN

KNAUPER V, WILHELM SM, SEPERACK PK, DECLERCK YA, LANGLEY KE, OSTHUES A, Tschesche H (1993)
BIOCHEMICAL JOURNAL 295: 581-586.

Download
No fulltext has been uploaded. References only!
Journal Article | Original Article | Published | English

No fulltext has been uploaded

Author
; ; ; ; ; ;
Abstract
Human neutrophil procollagenase was activated by incubation with recombinant active stromelysin. Activation was achieved by cleavage of the Gly78-Phe79 peptide bond at the end of the propeptide domain in a single-step activation mechanism. In addition, accelerated activation was achieved when N-terminally truncated, latent collagenase (with Phe49 as its N-terminal residue) was incubated with recombinant active stromelysin. Determination of the specific activity of recombinant-stromelysin-activated neutrophil collagenase with dinitrophenyl-octapeptide or type I collagen demonstrated the generation of high specific activity. The specific activity of stromelysin-activated enzyme was considerably higher than that of trypsin- or HgCl2-activated collagenase. Thus human neutrophil collagenase is superactivated, like the homologous fibroblast collagenase [Murphy, Cockett, Stephens, Smith and Docherty (1987) Biochem. J. 248, 265-268]. The occurrence of Phe79 at the N-terminus of the neutrophil collagenase seemed to be critical for superactivation, which is in agreement with data published Suzuki. Enghild, Morodomi, Salvesen and Nagase [(1990) Biochemistry 29. 10261-10270] on fibroblast collagenase.
Publishing Year
ISSN
PUB-ID

Cite this

KNAUPER V, WILHELM SM, SEPERACK PK, et al. DIRECT ACTIVATION OF HUMAN NEUTROPHIL PROCOLLAGENASE BY RECOMBINANT STROMELYSIN. BIOCHEMICAL JOURNAL. 1993;295:581-586.
KNAUPER, V., WILHELM, S. M., SEPERACK, P. K., DECLERCK, Y. A., LANGLEY, K. E., OSTHUES, A., & Tschesche, H. (1993). DIRECT ACTIVATION OF HUMAN NEUTROPHIL PROCOLLAGENASE BY RECOMBINANT STROMELYSIN. BIOCHEMICAL JOURNAL, 295, 581-586.
KNAUPER, V., WILHELM, S. M., SEPERACK, P. K., DECLERCK, Y. A., LANGLEY, K. E., OSTHUES, A., and Tschesche, H. (1993). DIRECT ACTIVATION OF HUMAN NEUTROPHIL PROCOLLAGENASE BY RECOMBINANT STROMELYSIN. BIOCHEMICAL JOURNAL 295, 581-586.
KNAUPER, V., et al., 1993. DIRECT ACTIVATION OF HUMAN NEUTROPHIL PROCOLLAGENASE BY RECOMBINANT STROMELYSIN. BIOCHEMICAL JOURNAL, 295, p 581-586.
V. KNAUPER, et al., “DIRECT ACTIVATION OF HUMAN NEUTROPHIL PROCOLLAGENASE BY RECOMBINANT STROMELYSIN”, BIOCHEMICAL JOURNAL, vol. 295, 1993, pp. 581-586.
KNAUPER, V., WILHELM, S.M., SEPERACK, P.K., DECLERCK, Y.A., LANGLEY, K.E., OSTHUES, A., Tschesche, H.: DIRECT ACTIVATION OF HUMAN NEUTROPHIL PROCOLLAGENASE BY RECOMBINANT STROMELYSIN. BIOCHEMICAL JOURNAL. 295, 581-586 (1993).
KNAUPER, V, WILHELM, SM, SEPERACK, PK, DECLERCK, YA, LANGLEY, KE, OSTHUES, A, and Tschesche, Harald. “DIRECT ACTIVATION OF HUMAN NEUTROPHIL PROCOLLAGENASE BY RECOMBINANT STROMELYSIN”. BIOCHEMICAL JOURNAL 295 (1993): 581-586.
This data publication is cited in the following publications:
This publication cites the following data publications:

71 Citations in Europe PMC

Data provided by Europe PubMed Central.

Comparison of rapid MMP-8 and interleukin-6 point-of-care tests to identify intra-amniotic inflammation/infection and impending preterm delivery in patients with preterm labor and intact membranes.
Chaemsaithong P, Romero R, Docheva N, Chaiyasit N, Bhatti G, Pacora P, Hassan SS, Yeo L, Erez O., J. Matern. Fetal. Neonatal. Med. 31(2), 2018
PMID: 28081646
Chitosan enriched three-dimensional matrix reduces inflammatory and catabolic mediators production by human chondrocytes.
Oprenyeszk F, Sanchez C, Dubuc JE, Maquet V, Henrist C, Compere P, Henrotin Y., PLoS ONE 10(5), 2015
PMID: 26020773
MMP-1 and -3 haplotype is associated with congenital anomalies of the kidney and urinary tract.
Djuric T, Zivkovic M, Milosevic B, Andjelevski M, Cvetkovic M, Kostic M, Stankovic A., Pediatr. Nephrol. 29(5), 2014
PMID: 24414606
Ovarian expression and regulation of the stromelysins during the periovulatory period in the human and the rat.
McCord LA, Li F, Rosewell KL, Brannstrom M, Curry TE., Biol. Reprod. 86(3), 2012
PMID: 22116802
Collagen I regulates matrix metalloproteinase-2 activation in osteosarcoma cells independent of S100A4.
Elenjord R, Allen JB, Johansen HT, Kildalsen H, Svineng G, Maelandsmo GM, Loennechen T, Winberg JO., FEBS J. 276(18), 2009
PMID: 19682073
Immunological investigation of the hepatic tissue from infants with biliary atresia.
Baba H, Ohtsuka Y, Fujii T, Haruna H, Nagata S, Kobayashi H, Yamataka A, Shimizu T, Miyano T, Yamashiro Y., Pediatr. Surg. Int. 25(2), 2009
PMID: 19089432
Spontaneous metastasis in matrix metalloproteinase 3-deficient mice.
Juncker-Jensen A, Romer J, Pennington CJ, Lund LR, Almholt K., Mol. Carcinog. 48(7), 2009
PMID: 19058297
Effect of collagen turnover and matrix metalloproteinase activity on healing of venous leg ulcers.
Meyer FJ, Burnand KG, Abisi S, Tekoppele JM, van Els B, Smith A., Br J Surg 95(3), 2008
PMID: 17854113
Dysregulation of renal MMP-3 and MMP-7 in canine X-linked Alport syndrome.
Rao VH, Lees GE, Kashtan CE, Delimont DC, Singh R, Meehan DT, Bhattacharya G, Berridge BR, Cosgrove D., Pediatr. Nephrol. 20(6), 2005
PMID: 15782307
Structure, expression, and developmental function of early divergent forms of metalloproteinases in hydra.
Sarras MP Jr, Yan L, Leontovich A, Zhang JS., Cell Res. 12(3-4), 2002
PMID: 12296376
Association of trypsin-2 with activation of gelatinase B and collagenase-2 in human bronchoalveolar lavage fluid in vivo.
Prikk K, Maisi P, Sepper R, Stenman UH, Salo T, Sorsa T., Ann. Med. 33(6), 2001
PMID: 11585105
The cleavage of pro-urokinase type plasminogen activator by stromelysin-1.
Orgel D, Schroder W, Hecker-Kia A, Weithmann KU, Kolkenbrock H, Ulbrich N., Clin. Chem. Lab. Med. 36(9), 1998
PMID: 9804393
Mast cells in bronchiectasis.
Sepper R, Konttinen YT, Kemppinen P, Sorsa T, Eklund KK., Ann. Med. 30(3), 1998
PMID: 9677018
A matrix metalloproteinase proenzyme activator produced by articular cartilage.
Towle CA, Wright M, Hecht AC, Kuong SJ, Papanicolas LE, Totkovic R, Mankin HJ, Treadwell BV., Biochem. Biophys. Res. Commun. 247(2), 1998
PMID: 9642125
Neutrophil procollagenase can be activated by stromelysin-2.
Knauper V, Murphy G, Tschesche H., Ann. N. Y. Acad. Sci. 732(), 1994
PMID: 7978810

Export

0 Marked Publications

Open Data PUB

Web of Science

View record in Web of Science®

Sources

PMID: 8240261
PubMed | Europe PMC

Search this title in

Google Scholar