INTERLEUKIN-8 SYNTHESIS AND THE ONSET OF LABOR

OSMERS RGW, BLASER J, KUHN W, Tschesche H (1995)
OBSTETRICS AND GYNECOLOGY 86(2): 223-229.

Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Autor
; ; ;
Abstract / Bemerkung
Objective: To examine the role of cytokines in cervical dilation. Methods: In 55 patients undergoing cesarean delivery, we took samples from the lower uterine segment, the decidua, and the membranes. We determined the concentrations of interleukin (IL)-2, IL-8, tumor necrosis factor-alpha, matrix metalloproteinase (MMP)-8, and MMP-9 in the different tissues. Results: Depending on the state of labor, we observed a significant increase (P < .001) in IL-8 concentrations in the lower uterine segment. The leukocyte enzymes MMP-8 and MMP-9 were highly significantly correlated with the IL-8 concentrations. Conclusion: Interleukin-8 is critically involved in the process of parturition in humans. Interleukin-6 concentrations in the myometrium, decidua, and membranes correlated strongly with the observed MMP-8 and MMP-9 concentrations.
Erscheinungsjahr
Zeitschriftentitel
OBSTETRICS AND GYNECOLOGY
Band
86
Zeitschriftennummer
2
Seite
223-229
ISSN
PUB-ID

Zitieren

OSMERS RGW, BLASER J, KUHN W, Tschesche H. INTERLEUKIN-8 SYNTHESIS AND THE ONSET OF LABOR. OBSTETRICS AND GYNECOLOGY. 1995;86(2):223-229.
OSMERS, R. G. W., BLASER, J., KUHN, W., & Tschesche, H. (1995). INTERLEUKIN-8 SYNTHESIS AND THE ONSET OF LABOR. OBSTETRICS AND GYNECOLOGY, 86(2), 223-229. doi:10.1016/0029-7844(95)93704-4
OSMERS, R. G. W., BLASER, J., KUHN, W., and Tschesche, H. (1995). INTERLEUKIN-8 SYNTHESIS AND THE ONSET OF LABOR. OBSTETRICS AND GYNECOLOGY 86, 223-229.
OSMERS, R.G.W., et al., 1995. INTERLEUKIN-8 SYNTHESIS AND THE ONSET OF LABOR. OBSTETRICS AND GYNECOLOGY, 86(2), p 223-229.
R.G.W. OSMERS, et al., “INTERLEUKIN-8 SYNTHESIS AND THE ONSET OF LABOR”, OBSTETRICS AND GYNECOLOGY, vol. 86, 1995, pp. 223-229.
OSMERS, R.G.W., BLASER, J., KUHN, W., Tschesche, H.: INTERLEUKIN-8 SYNTHESIS AND THE ONSET OF LABOR. OBSTETRICS AND GYNECOLOGY. 86, 223-229 (1995).
OSMERS, RGW, BLASER, J, KUHN, W, and Tschesche, Harald. “INTERLEUKIN-8 SYNTHESIS AND THE ONSET OF LABOR”. OBSTETRICS AND GYNECOLOGY 86.2 (1995): 223-229.

110 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

The importance of extracellular matrix in the induction of preterm delivery.
Rath W, Winkler M, Kemp B., J Perinat Med 26(6), 1998
PMID: 10224599
Pathogenesis of preterm labor and preterm premature rupture of membranes associated with intraamniotic infection.
Gomez R, Romero R, Edwin SS, David C., Infect Dis Clin North Am 11(1), 1997
PMID: 9067790
Maternal serum granulocyte-colony stimulating factor in preterm birth with subclinical chorioamnionitis.
Boggess KA, Greig PC, Murtha AP, Jimmerson CE, Herbert WN., J Reprod Immunol 33(1), 1997
PMID: 9185076
Interleukin-8 is a mediator of the final cervical ripening in humans.
Sennström MK, Brauner A, Lu Y, Granström LM, Malmström AL, Ekman GE., Eur J Obstet Gynecol Reprod Biol 74(1), 1997
PMID: 9243210
The inhibition of synthesis of a beta-chemokine, monocyte chemotactic protein-1 (MCP-1) by progesterone.
Kelly RW, Carr GG, Riley SC., Biochem Biophys Res Commun 239(2), 1997
PMID: 9344869
Inflammatory cytokine mRNA in human gestational tissues: implications for term and preterm labor.
Dudley DJ, Collmer D, Mitchell MD, Trautman MS., J Soc Gynecol Investig 3(6), 1996
PMID: 8923417
Regulation of cultured human chorion cell chemokine production by group B streptococci and purified bacterial products.
Dudley DJ, Edwin SS, Dangerfield A, Van Waggoner J, Mitchell MD., Am J Reprod Immunol 36(5), 1996
PMID: 8955503
Mechanical stretching induces interleukin-8 gene expression in fetal membranes: a possible role for the initiation of human parturition.
Maehara K, Kanayama N, Maradny EE, Uezato T, Fujita M, Terao T., Eur J Obstet Gynecol Reprod Biol 70(2), 1996
PMID: 9119102

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 7617353
PubMed | Europe PMC

Suchen in

Google Scholar