INHIBITION OF DEGRANULATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES BY COMPLEMENT-FACTOR-D

BALKE N, HOLTKAMP U, HORL WH, Tschesche H (1995)
FEBS LETTERS 371(3): 300-302.

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Abstract
A degranulation inhibiting protein could be isolated from human plasma ultrafiltrate by a three-step purification method including ion-exchange chromatography gelfiltration and affinity-chromatography. The protein was identified as complement factor D by means of sequence analysis, Its degranulation inhibiting activity was determined with regard to its effect on the FNLPNTL-induced lactoferrin secretion of human polymorphonuclear leukocytes. Complement factor D caused a dose-dependent decrease of the FNLPNTL-stimulated lactoferrin degranulation down to 34% of stimulated controls.
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BALKE N, HOLTKAMP U, HORL WH, Tschesche H. INHIBITION OF DEGRANULATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES BY COMPLEMENT-FACTOR-D. FEBS LETTERS. 1995;371(3):300-302.
BALKE, N., HOLTKAMP, U., HORL, W. H., & Tschesche, H. (1995). INHIBITION OF DEGRANULATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES BY COMPLEMENT-FACTOR-D. FEBS LETTERS, 371(3), 300-302.
BALKE, N., HOLTKAMP, U., HORL, W. H., and Tschesche, H. (1995). INHIBITION OF DEGRANULATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES BY COMPLEMENT-FACTOR-D. FEBS LETTERS 371, 300-302.
BALKE, N., et al., 1995. INHIBITION OF DEGRANULATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES BY COMPLEMENT-FACTOR-D. FEBS LETTERS, 371(3), p 300-302.
N. BALKE, et al., “INHIBITION OF DEGRANULATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES BY COMPLEMENT-FACTOR-D”, FEBS LETTERS, vol. 371, 1995, pp. 300-302.
BALKE, N., HOLTKAMP, U., HORL, W.H., Tschesche, H.: INHIBITION OF DEGRANULATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES BY COMPLEMENT-FACTOR-D. FEBS LETTERS. 371, 300-302 (1995).
BALKE, N, HOLTKAMP, U, HORL, WH, and Tschesche, Harald. “INHIBITION OF DEGRANULATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES BY COMPLEMENT-FACTOR-D”. FEBS LETTERS 371.3 (1995): 300-302.
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