Amides from the Stem Bark of Fagara macrophylla

Wansi J, Nwozo SO, Mbaze LM'a, Devkota KP, Moladje SMD, Fornum ZT, Sewald N (2009)
PLANTA MEDICA 75(05): 517-521.

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Zeitschriftenaufsatz | Veröffentlicht | Englisch
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Abstract / Bemerkung
Five new amide alkaloids, N-(4-hydroxyphenethyl)octacosanamide (1), N-(4-hydroxyphenethyl)hexacosanamide (2), N-(4-hydroxyphenethyl)decanamide (3), N-vanilloyltyramine (4), and N-[O-docosanoylvanilloyl]tyramine (5), were isolated from Fagara macrophylla, together with 15 known compounds. Their structures were established by using spectroscopic techniques, chemical reactions, and comparison with previously known analogues. A cytotoxicity assay was performed with the isolates, in which compounds 4, 8, and 9 were found to possess moderate to weak activity, with IC50 values of 30.5, 11.5, and 13.5 mu g/mL, respectively.
Erscheinungsjahr
Zeitschriftentitel
PLANTA MEDICA
Band
75
Zeitschriftennummer
05
Seite
517-521
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Wansi J, Nwozo SO, Mbaze LM'a, et al. Amides from the Stem Bark of Fagara macrophylla. PLANTA MEDICA. 2009;75(05):517-521.
Wansi, J., Nwozo, S. O., Mbaze, L. M. 'a, Devkota, K. P., Moladje, S. M. D., Fornum, Z. T., & Sewald, N. (2009). Amides from the Stem Bark of Fagara macrophylla. PLANTA MEDICA, 75(05), 517-521. doi:10.1055/s-0029-1185327
Wansi, J., Nwozo, S. O., Mbaze, L. M. 'a, Devkota, K. P., Moladje, S. M. D., Fornum, Z. T., and Sewald, N. (2009). Amides from the Stem Bark of Fagara macrophylla. PLANTA MEDICA 75, 517-521.
Wansi, J., et al., 2009. Amides from the Stem Bark of Fagara macrophylla. PLANTA MEDICA, 75(05), p 517-521.
J. Wansi, et al., “Amides from the Stem Bark of Fagara macrophylla”, PLANTA MEDICA, vol. 75, 2009, pp. 517-521.
Wansi, J., Nwozo, S.O., Mbaze, L.M.'a, Devkota, K.P., Moladje, S.M.D., Fornum, Z.T., Sewald, N.: Amides from the Stem Bark of Fagara macrophylla. PLANTA MEDICA. 75, 517-521 (2009).
Wansi, Jean, Nwozo, Sarah Onyenibe, Mbaze, Luc Meva'a, Devkota, Krishna Prasad, Moladje, Suzye Mireille Donkwe, Fornum, Zacharias Tanee, and Sewald, Norbert. “Amides from the Stem Bark of Fagara macrophylla”. PLANTA MEDICA 75.05 (2009): 517-521.

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Mehmood R, Imran M, Safder M, Anjum S, Malik A., J Asian Nat Prod Res 12(8), 2010
PMID: 20706901

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