Novelty and familiarity activations in PET studies of memory encoding and retrieval

Tulving E, Markowitsch HJ, Craik FIM, Habib R, Houle S (1996)
CEREBRAL CORTEX 6(1): 71-79.

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Nine young right-handed men viewed colored pictures of people, scenes, and landscapes. Then, 24 hr later while undergoing PET scanning, they viewed previously studied (OLD) pictures in one type of scan, and previously not seen (NEW) pictures in another. The OLD-NEW subtraction of PET images indicates familiarity, and the NEW-OLD indicates novelty. Familiarity activations, signalling aspects of retrieval, were observed in the left and right frontal areas, and posterior regions bilaterally. Novelty activations were in the right limbic regions, and bilaterally in temporal and parietal regions, including area 37. These latter activations were located similarly to novelty activations in previous PET studies using visual words and auditory sentences, suggesting the existence of brain regions specializing in transmodal novelty assessment. The effects of novelty are seen both behaviorally and in replicable patterns of cortical and subcortical activation. We propose a ''novelty/encoding hypothesis'': (1) novelty assessment represents an early stage of long-term memory encoding; (2) elaborate, meaning-based encoding processes operate on the incoming information to the extent of its novelty, and therefore (3) the probability of long-term storage of information varies directly with the novelty of the information.
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Tulving E, Markowitsch HJ, Craik FIM, Habib R, Houle S. Novelty and familiarity activations in PET studies of memory encoding and retrieval. CEREBRAL CORTEX. 1996;6(1):71-79.
Tulving, E., Markowitsch, H. J., Craik, F. I. M., Habib, R., & Houle, S. (1996). Novelty and familiarity activations in PET studies of memory encoding and retrieval. CEREBRAL CORTEX, 6(1), 71-79. doi:10.1093/cercor/6.1.71
Tulving, E., Markowitsch, H. J., Craik, F. I. M., Habib, R., and Houle, S. (1996). Novelty and familiarity activations in PET studies of memory encoding and retrieval. CEREBRAL CORTEX 6, 71-79.
Tulving, E., et al., 1996. Novelty and familiarity activations in PET studies of memory encoding and retrieval. CEREBRAL CORTEX, 6(1), p 71-79.
E. Tulving, et al., “Novelty and familiarity activations in PET studies of memory encoding and retrieval”, CEREBRAL CORTEX, vol. 6, 1996, pp. 71-79.
Tulving, E., Markowitsch, H.J., Craik, F.I.M., Habib, R., Houle, S.: Novelty and familiarity activations in PET studies of memory encoding and retrieval. CEREBRAL CORTEX. 6, 71-79 (1996).
Tulving, E, Markowitsch, Hans J., Craik, FIM, Habib, R, and Houle, S. “Novelty and familiarity activations in PET studies of memory encoding and retrieval”. CEREBRAL CORTEX 6.1 (1996): 71-79.
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Associative encoding of pictures activates the medial temporal lobes.
Montaldi D, Mayes AR, Barnes A, Pirie H, Hadley DM, Patterson J, Wyper DJ., Hum Brain Mapp 6(2), 1998
PMID: 9673665
Analysis of fMRI data by blind separation into independent spatial components.
McKeown MJ, Makeig S, Brown GG, Jung TP, Kindermann SS, Bell AJ, Sejnowski TJ., Hum Brain Mapp 6(3), 1998
PMID: 9673671
Cortico-limbic circuits and novelty: a review of EEG and blood flow data.
Knight RT, Nakada T., Rev Neurosci 9(1), 1998
PMID: 9683327
Human hippocampus establishes associations in memory.
Henke K, Buck A, Weber B, Wieser HG., Hippocampus 7(3), 1997
PMID: 9228523
Modulation of human medial temporal lobe activity by form, meaning, and experience.
Martin A, Wiggs CL, Weisberg J., Hippocampus 7(6), 1997
PMID: 9443055
Imaging Cognition: An Empirical Review of PET Studies with Normal Subjects.
Cabeza R, Nyberg L., J Cogn Neurosci 9(1), 1997
PMID: 23968177
Functional Neuroanatomy of Recall and Recognition: A PET Study of Episodic Memory.
Cabeza R, Kapur S, Craik FI, McIntosh AR, Houle S, Tulving E., J Cogn Neurosci 9(2), 1997
PMID: 23962015
Memory beyond the hippocampus.
Tulving E, Markowitsch HJ., Curr Opin Neurobiol 7(2), 1997
PMID: 9142753
Event-related brain potential correlates of two states of conscious awareness in memory.
Düzel E, Yonelinas AP, Mangun GR, Heinze HJ, Tulving E., Proc Natl Acad Sci U S A 94(11), 1997
PMID: 9159185
Factors that influence effect size in 15O PET studies: a meta-analytic review.
Gold S, Arndt S, Johnson D, O'Leary DS, Andreasen NC., Neuroimage 5(4 pt 1), 1997
PMID: 9345557
A PET Study of Persistent Psychogenic Amnesia Covering the Whole Life Span.
Markowitsch HJ, Fink GR, Thone A, Kessler J, Heiss WD., Cogn Neuropsychiatry 2(2), 1997
PMID: 25420201
Positron-emission tomography imaging of long-term shape recognition challenges.
Rosier A, Cornette L, Dupont P, Bormans G, Michiels J, Mortelmans L, Orban GA., Proc Natl Acad Sci U S A 94(14), 1997
PMID: 9207143
A dynamic role of the medial temporal lobe during retrieval of declarative memory in man.
Petersson KM, Elfgren C, Ingvar M., Neuroimage 6(1), 1997
PMID: 9245651
Dissociating prefrontal and hippocampal function in episodic memory encoding.
Dolan RJ, Fletcher PC., Nature 388(6642), 1997
PMID: 9252188
A trial-based experimental design for fMRI.
Zarahn E, Aguirre G, D'Esposito M., Neuroimage 6(2), 1997
PMID: 9299386
Brain regions differentially involved in remembering what and when: a PET study.
Cabeza R, Mangels J, Nyberg L, Habib R, Houle S, McIntosh AR, Tulving E., Neuron 19(4), 1997
PMID: 9354332
Hippocampal synaptic plasticity: role in spatial learning or the automatic recording of attended experience?
Morris RG, Frey U., Philos Trans R Soc Lond B Biol Sci 352(1360), 1997
PMID: 9368938
Semantic aspects of novelty detection in humans.
Mecklinger A, Opitz B, Friederici AD., Neurosci Lett 235(1-2), 1997
PMID: 9389597
Right temporofrontal cortex as critical locus for the ecphory of old episodic memories.
Calabrese P, Markowitsch HJ, Durwen HF, Widlitzek H, Haupts M, Holinka B, Gehlen W., J Neurol Neurosurg Psychiatry 61(3), 1996
PMID: 8795604
General and specific brain regions involved in encoding and retrieval of events: what, where, and when.
Nyberg L, McIntosh AR, Cabeza R, Habib R, Houle S, Tulving E., Proc Natl Acad Sci U S A 93(20), 1996
PMID: 8855347

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