Angiogenin plasma levels during pregnancy

Kolben M, Blaser J, Ulm K, Schmitt M, Schneider KTM, Tschesche H, Graeff H (1997)
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 176(1): 37-41.

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Abstract
OBJECTIVE: Our purpose was to determine the levels in plasma of angiogenin in healthy pregnant women and to examine whether there are differences between uncomplicated pregnancies and patients with the syndrome of hemolysis, elevated liver enzymes, and low platelets, preeclampsia-eclampsia, and highly pathologic Doppler flow findings without additional complications. STUDY DESIGN: Angiogenin was measured with a novel enzyme-linked immunosorbent assay. A case control and observational study was conducted in 68 healthy women from the tenth to fortieth weeks of pregnancy and in 18 patients with the syndrome of hemolysis, elevated liver enzymes, and low platelets, 21 with preeclampsia/eclampsia and 13 with highly pathologic Doppler flow findings at admission for delivery. RESULTS: Between the tenth and fortieth weeks of uncomplicated pregnancy angiogenin plasma levels rose from 150 to 250 ng/ml (significant correlation). In patients with highly pathologic Doppler flow findings angiogenin is significantly reduced compared with healthy pregnant matched pairs (150 vs 219 ng/ml, p < 0.01). CONCLUSION: Rising plasma angiogenin levels in pregnancy may reflect persisting placental transformation and remodeling processes; in patients with highly pathologic Doppler flow findings these processes are disturbed and thus placental function is impaired.
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Kolben M, Blaser J, Ulm K, et al. Angiogenin plasma levels during pregnancy. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 1997;176(1):37-41.
Kolben, M., Blaser, J., Ulm, K., Schmitt, M., Schneider, K. T. M., Tschesche, H., & Graeff, H. (1997). Angiogenin plasma levels during pregnancy. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 176(1), 37-41.
Kolben, M., Blaser, J., Ulm, K., Schmitt, M., Schneider, K. T. M., Tschesche, H., and Graeff, H. (1997). Angiogenin plasma levels during pregnancy. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 176, 37-41.
Kolben, M., et al., 1997. Angiogenin plasma levels during pregnancy. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 176(1), p 37-41.
M. Kolben, et al., “Angiogenin plasma levels during pregnancy”, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, vol. 176, 1997, pp. 37-41.
Kolben, M., Blaser, J., Ulm, K., Schmitt, M., Schneider, K.T.M., Tschesche, H., Graeff, H.: Angiogenin plasma levels during pregnancy. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 176, 37-41 (1997).
Kolben, M, Blaser, J, Ulm, K, Schmitt, M, Schneider, KTM, Tschesche, Harald, and Graeff, H. “Angiogenin plasma levels during pregnancy”. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 176.1 (1997): 37-41.
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Angiogenin: a review of the pathophysiology and potential clinical applications.
Tello-Montoliu A, Patel JV, Lip GY., J. Thromb. Haemost. 4(9), 2006
PMID: 16961595
Circulating angiogenic factors in preeclampsia.
Levine RJ, Karumanchi SA., Clin Obstet Gynecol 48(2), 2005
PMID: 15805796
Angiogenin and vascular endothelial growth factor in pregnancies complicated by preeclampsia.
Shaarawy M, Al-Sokkary F, Sheba M, Wahba O, Kandil HO, Abdel-Mohsen I., Int J Gynaecol Obstet 88(2), 2005
PMID: 15694084
Aspects of human fetoplacental vasculogenesis and angiogenesis. III. Changes in complicated pregnancies.
Mayhew TM, Charnock-Jones DS, Kaufmann P., Placenta 25(2-3), 2004
PMID: 14972445
Angiogenin and gestational trophoblastic tumors, a promising prognostic marker.
Shaarawy M, El-Mallah SY, Sheiba M., Clin. Chem. Lab. Med. 41(3), 2003
PMID: 12705339
Expression and localization of angiogenin in placenta: enhanced levels at term over first trimester villi.
Rajashekhar G, Loganath A, Roy AC, Wong YC., Mol. Reprod. Dev. 62(2), 2002
PMID: 11984825
Postpartum curettage in patients with HELLP-syndrome does not result in accelerated recovery.
Schlenzig C, Maurer S, Goppelt M, Ulm K, Kolben M., Eur. J. Obstet. Gynecol. Reprod. Biol. 91(1), 2000
PMID: 10817874

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