Expression of the potassium channel KV3.4 in mouse skeletal muscle parallels fiber type maturation and depends on excitation pattern

Vullhorst D, Klocke R, Bartsch JW, Jockusch H (1998)
FEBS letters 421(3): 259-262.

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Abstract
We report the detailed expression pattern of the voltage-dependent potassium channel KV3.4 (rat homologue, Raw3) in mouse skeletal muscle, Using semi-quantitative RT-PCR, we show that its expression is detectable at embryonic day 17 and rises to adult levels within 2 weeks after birth, Expression is fiber type-dependent, with mRNA levels being 5-6-fold lower in the mixed slow/fast soleus muscle than in the fast tibialis anterior and extensor digitorum longus muscles, Fast muscles from myotonic mice exhibit low KV3.4 mRNA levels similar to those of wild-type soleus, In denervated extensor digitorum longus, KV3.4 expression declines to perinatal levels. We conclude that KV3.4 expression in mouse skeletal muscle is regulated by the pattern of excitation. (C) 1998 Federation of European Biochemical Societies.
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Vullhorst D, Klocke R, Bartsch JW, Jockusch H. Expression of the potassium channel KV3.4 in mouse skeletal muscle parallels fiber type maturation and depends on excitation pattern. FEBS letters. 1998;421(3):259-262.
Vullhorst, D., Klocke, R., Bartsch, J. W., & Jockusch, H. (1998). Expression of the potassium channel KV3.4 in mouse skeletal muscle parallels fiber type maturation and depends on excitation pattern. FEBS letters, 421(3), 259-262.
Vullhorst, D., Klocke, R., Bartsch, J. W., and Jockusch, H. (1998). Expression of the potassium channel KV3.4 in mouse skeletal muscle parallels fiber type maturation and depends on excitation pattern. FEBS letters 421, 259-262.
Vullhorst, D., et al., 1998. Expression of the potassium channel KV3.4 in mouse skeletal muscle parallels fiber type maturation and depends on excitation pattern. FEBS letters, 421(3), p 259-262.
D. Vullhorst, et al., “Expression of the potassium channel KV3.4 in mouse skeletal muscle parallels fiber type maturation and depends on excitation pattern”, FEBS letters, vol. 421, 1998, pp. 259-262.
Vullhorst, D., Klocke, R., Bartsch, J.W., Jockusch, H.: Expression of the potassium channel KV3.4 in mouse skeletal muscle parallels fiber type maturation and depends on excitation pattern. FEBS letters. 421, 259-262 (1998).
Vullhorst, D, Klocke, R, Bartsch, JW, and Jockusch, Harald. “Expression of the potassium channel KV3.4 in mouse skeletal muscle parallels fiber type maturation and depends on excitation pattern”. FEBS letters 421.3 (1998): 259-262.
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