Rose: generating sequence families

Stoye J, Evers D, Meyer F (1998)
BIOINFORMATICS 14(2): 157-163.

Download
OA
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Autor
; ;
Abstract / Bemerkung
Motivation: We present a new probabilistic model of the evolution of RNA-, DNA-, ol protein-like sequences and a software tool, Rose, that implements this model. Guided by an evolutionary tree, a family of related sequences is created from a common ancestor sequence by insertion, deletion and substitution of characters. During this artificial evolutionary process, the 'true' history is logged and the 'correct' multiple sequence alignment is created simultaneously The model also allows for varying rates of mutation within the sequences, making it possible to establish so-called sequence motifs. Results: The data created by Rose are suitable for the evaluation of methods in multiple sequence alignment computation and the prediction of phylogenetic relationships. It can also be useful when reaching courses in or developing models of sequence evolution and in the study of evolutionary processes.
Erscheinungsjahr
Zeitschriftentitel
BIOINFORMATICS
Band
14
Zeitschriftennummer
2
Seite
157-163
ISSN
eISSN
PUB-ID

Zitieren

Stoye J, Evers D, Meyer F. Rose: generating sequence families. BIOINFORMATICS. 1998;14(2):157-163.
Stoye, J., Evers, D., & Meyer, F. (1998). Rose: generating sequence families. BIOINFORMATICS, 14(2), 157-163. doi:10.1093/bioinformatics/14.2.157
Stoye, J., Evers, D., and Meyer, F. (1998). Rose: generating sequence families. BIOINFORMATICS 14, 157-163.
Stoye, J., Evers, D., & Meyer, F., 1998. Rose: generating sequence families. BIOINFORMATICS, 14(2), p 157-163.
J. Stoye, D. Evers, and F. Meyer, “Rose: generating sequence families”, BIOINFORMATICS, vol. 14, 1998, pp. 157-163.
Stoye, J., Evers, D., Meyer, F.: Rose: generating sequence families. BIOINFORMATICS. 14, 157-163 (1998).
Stoye, Jens, Evers, Dirk, and Meyer, Folker. “Rose: generating sequence families”. BIOINFORMATICS 14.2 (1998): 157-163.
Alle Dateien verfügbar unter der/den folgenden Lizenz(en):
Copyright Statement:
This Item is protected by copyright and/or related rights. [...]
Volltext(e)
Access Level
OA Open Access
Zuletzt Hochgeladen
1970-01-01T00:00:00Z

108 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

ThurGood: evaluating assembly-to-assembly mapping.
Shatkay H, Miller J, Mobarry C, Flanigan M, Yooseph S, Sutton G., J Comput Biol 11(5), 2004
PMID: 15700403
Benchmarking tools for the alignment of functional noncoding DNA.
Pollard DA, Bergman CM, Stoye J, Celniker SE, Eisen MB., BMC Bioinformatics 5(), 2004
PMID: 14736341
Fast and sensitive multiple alignment of large genomic sequences.
Brudno M, Chapman M, Göttgens B, Batzoglou S, Morgenstern B., BMC Bioinformatics 4(), 2003
PMID: 14693042
Algorithms for phylogenetic footprinting.
Blanchette M, Schwikowski B, Tompa M., J Comput Biol 9(2), 2002
PMID: 12015878
Quality assessment of multiple alignment programs.
Lassmann T, Sonnhammer EL., FEBS Lett 529(1), 2002
PMID: 12354624

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 9545448
PubMed | Europe PMC

Suchen in

Google Scholar