Synthesis and reduction of endothiodipeptides containing malonic acid derivatives

Krumme D, Tschesche H (1999)
TETRAHEDRON 55(10): 3007-3018.

Journal Article | Published | English

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Amides of malonic acid derivatives and protected dipeptides containing amino malonic acid have been synthesized and converted into the corresponding monothio analoga and endothiodipeptides. By reduction of the thioamides terminal protected beta-carboxy amino derivatives were obtained. Reduction of endothiodipeptides containing amino malonic acid as the carboxy component resulted in protected Psi[CH2NH] pseudodipeptides for the use as dipeptide substitutes with proteolytic resistance. (C) 1999 Elsevier Science Ltd. All rights reserved.
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Krumme D, Tschesche H. Synthesis and reduction of endothiodipeptides containing malonic acid derivatives. TETRAHEDRON. 1999;55(10):3007-3018.
Krumme, D., & Tschesche, H. (1999). Synthesis and reduction of endothiodipeptides containing malonic acid derivatives. TETRAHEDRON, 55(10), 3007-3018.
Krumme, D., and Tschesche, H. (1999). Synthesis and reduction of endothiodipeptides containing malonic acid derivatives. TETRAHEDRON 55, 3007-3018.
Krumme, D., & Tschesche, H., 1999. Synthesis and reduction of endothiodipeptides containing malonic acid derivatives. TETRAHEDRON, 55(10), p 3007-3018.
D. Krumme and H. Tschesche, “Synthesis and reduction of endothiodipeptides containing malonic acid derivatives”, TETRAHEDRON, vol. 55, 1999, pp. 3007-3018.
Krumme, D., Tschesche, H.: Synthesis and reduction of endothiodipeptides containing malonic acid derivatives. TETRAHEDRON. 55, 3007-3018 (1999).
Krumme, D, and Tschesche, Harald. “Synthesis and reduction of endothiodipeptides containing malonic acid derivatives”. TETRAHEDRON 55.10 (1999): 3007-3018.
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