Elevated expression of membrane type I metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system

Rathke-Hartlieb S, Budde P, Ewert S, Schlomann U, Staege MS, Jockusch H, Bartsch JW, Frey J (2000)
FEBS LETTERS 481(3): 227-234.

Download
Es wurde kein Volltext hochgeladen. Nur Publikationsnachweis!
Zeitschriftenaufsatz | Veröffentlicht | Englisch
Autor
; ; ; ; ; ; ;
Abstract / Bemerkung
Reactive astrocytes occurring in response to neurodegeneration are thought to play an important role in neuronal regeneration by upregulating the expression of extracellular matrix (ECM) components as well as the ECM degrading metalloproteinases (MMPs). We examined the mRNA levels and cellular distribution of membrane type matrix metalloproteinase 1 (MT1-MMP) and tissue inhibitors 1-4 of MMPs (TIMPs) in brain stem and spinal cord of wobbler (WR) mutant mice affected by progressive neurodegeneration and astrogliosis. MT1-MMP, TIMP-1 and TIMP-3 mRNA levels were elevated, whereas TIMP-2 and TIMP-4 expression was not affected. MT1-MMP was expressed in reactive astrocytes of WR. In primary astrocyte cultures, MT1-MMP mRNA was upregulated by exogeneous tumor necrosis factor alpha. Increased plasma membrane and secreted MMP activities were found in primary WR astrocytes. (C) 2000 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.
Erscheinungsjahr
Zeitschriftentitel
FEBS LETTERS
Band
481
Ausgabe
3
Seite(n)
227-234
ISSN
PUB-ID

Zitieren

Rathke-Hartlieb S, Budde P, Ewert S, et al. Elevated expression of membrane type I metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system. FEBS LETTERS. 2000;481(3):227-234.
Rathke-Hartlieb, S., Budde, P., Ewert, S., Schlomann, U., Staege, M. S., Jockusch, H., Bartsch, J. W., et al. (2000). Elevated expression of membrane type I metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system. FEBS LETTERS, 481(3), 227-234. doi:10.1016/S0014-5793(00)02011-1
Rathke-Hartlieb, S., Budde, P., Ewert, S., Schlomann, U., Staege, M. S., Jockusch, H., Bartsch, J. W., and Frey, J. (2000). Elevated expression of membrane type I metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system. FEBS LETTERS 481, 227-234.
Rathke-Hartlieb, S., et al., 2000. Elevated expression of membrane type I metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system. FEBS LETTERS, 481(3), p 227-234.
S. Rathke-Hartlieb, et al., “Elevated expression of membrane type I metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system”, FEBS LETTERS, vol. 481, 2000, pp. 227-234.
Rathke-Hartlieb, S., Budde, P., Ewert, S., Schlomann, U., Staege, M.S., Jockusch, H., Bartsch, J.W., Frey, J.: Elevated expression of membrane type I metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system. FEBS LETTERS. 481, 227-234 (2000).
Rathke-Hartlieb, S, Budde, P, Ewert, S, Schlomann, U, Staege, MS, Jockusch, Harald, Bartsch, JW, and Frey, Jürgen. “Elevated expression of membrane type I metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system”. FEBS LETTERS 481.3 (2000): 227-234.

20 Zitationen in Europe PMC

Daten bereitgestellt von Europe PubMed Central.

Extracellular environment contribution to astrogliosis-lessons learned from a tissue engineered 3D model of the glial scar.
Rocha DN, Ferraz-Nogueira JP, Barrias CC, Relvas JB, Pêgo AP., Front Cell Neurosci 9(), 2015
PMID: 26483632
Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases.
Langenfurth A, Rinnenthal JL, Vinnakota K, Prinz V, Carlo AS, Stadelmann C, Siffrin V, Peaschke S, Endres M, Heppner F, Glass R, Wolf SA, Kettenmann H., J Neurosci Res 92(3), 2014
PMID: 24323769
Loss of vps54 function leads to vesicle traffic impairment, protein mis-sorting and embryonic lethality.
Karlsson P, Droce A, Moser JM, Cuhlmann S, Padilla CO, Heimann P, Bartsch JW, Füchtbauer A, Füchtbauer EM, Schmitt-John T., Int J Mol Sci 14(6), 2013
PMID: 23708095
The octadecaneuropeptide ODN protects astrocytes against hydrogen peroxide-induced apoptosis via a PKA/MAPK-dependent mechanism.
Hamdi Y, Kaddour H, Vaudry D, Bahdoudi S, Douiri S, Leprince J, Castel H, Vaudry H, Tonon MC, Amri M, Masmoudi-Kouki O., PLoS One 7(8), 2012
PMID: 22927932
Metalloproteinase alterations in the bone marrow of ALS patients.
Bossolasco P, Cova L, Calzarossa C, Servida F, Mencacci NE, Onida F, Polli E, Lambertenghi Deliliers G, Silani V., J Mol Med (Berl) 88(6), 2010
PMID: 20091292
ADAM8 is selectively up-regulated in endothelial cells and is associated with angiogenesis after spinal cord injury in adult mice.
Mahoney ET, Benton RL, Maddie MA, Whittemore SR, Hagg T., J Comp Neurol 512(2), 2009
PMID: 19003792
Matrix metalloproteinase-2 (MMP-2) regulates astrocyte motility in connection with the actin cytoskeleton and integrins.
Ogier C, Bernard A, Chollet AM, LE Diguardher T, Hanessian S, Charton G, Khrestchatisky M, Rivera S., Glia 54(4), 2006
PMID: 16845676
Astrocytes exert a pro-apoptotic effect on neurons in postnatal hippocampal cultures.
Shute AA, Cormier RJ, Moulder KL, Benz A, Isenberg KE, Zorumski CF, Mennerick S., Neuroscience 131(2), 2005
PMID: 15708478
The TIMPs tango with MMPs and more in the central nervous system.
Crocker SJ, Pagenstecher A, Campbell IL., J Neurosci Res 75(1), 2004
PMID: 14689443
The wobbler mouse: a neurodegeneration jigsaw puzzle.
Boillée S, Peschanski M, Junier MP., Mol Neurobiol 28(1), 2003
PMID: 14514986
Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia.
Suryadevara R, Holter S, Borgmann K, Persidsky R, Labenz-Zink C, Persidsky Y, Gendelman HE, Wu L, Ghorpade A., Glia 44(1), 2003
PMID: 12951656
Tissue inhibitor of metalloproteinase-3 is associated with neuronal death in reperfusion injury.
Wallace JA, Alexander S, Estrada EY, Hines C, Cunningham LA, Rosenberg GA., J Cereb Blood Flow Metab 22(11), 2002
PMID: 12439287
Membrane-type matrix metalloproteinases (MT-MMPs): expression and function during glioma invasion.
Fillmore HL, VanMeter TE, Broaddus WC., J Neurooncol 53(2), 2001
PMID: 11716070

41 References

Daten bereitgestellt von Europe PubMed Central.

Reactive astrocytes: cellular and molecular cues to biological function.
Ridet JL, Malhotra SK, Privat A, Gage FH., Trends Neurosci. 20(12), 1997
PMID: 9416670
Extracellular matrix degradation by metalloproteinases and central nervous system diseases.
Lukes A, Mun-Bryce S, Lukes M, Rosenberg GA., Mol. Neurobiol. 19(3), 1999
PMID: 10495107
Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.
Gomez DE, Alonso DF, Yoshiji H, Thorgeirsson UP., Eur. J. Cell Biol. 74(2), 1997
PMID: 9352216
Matrix metalloproteinase-2 activation modulates glioma cell migration.
Deryugina EI, Bourdon MA, Luo GX, Reisfeld RA, Strongin A., J. Cell. Sci. 110 ( Pt 19)(), 1997
PMID: 9410885
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.
Brooks PC, Stromblad S, Sanders LC, von Schalscha TL, Aimes RT, Stetler-Stevenson WG, Quigley JP, Cheresh DA., Cell 85(5), 1996
PMID: 8646777
Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate.
Lohi J, Lehti K, Westermarck J, Kahari VM, Keski-Oja J., Eur. J. Biochem. 239(2), 1996
PMID: 8706726
Wobbler, a mutation affecting motoneuron survival and gonadal functions in the mouse, maps to proximal chromosome 11.
Kaupmann K, Simon-Chazottes D, Guenet JL, Jockusch H., Genomics 13(1), 1992
PMID: 1349581
Spatiotemporal progression of neurodegeneration and glia activation in the wobbler neuropathy of the mouse.
Rathke-Hartlieb S, Schmidt VC, Jockusch H, Schmitt-John T, Bartsch JW., Neuroreport 10(16), 1999
PMID: 10599854
Transforming growth factor alpha (TGF alpha) expression in degenerating motoneurons of the murine mutant wobbler: a neuronal signal for astrogliosis?
Junier MP, Coulpier M, Le Forestier N, Cadusseau J, Suzuki F, Peschanski M, Dreyfus PA., J. Neurosci. 14(7), 1994
PMID: 8027772

Rathke-Hartlieb, J. Neurochem. 73(), 1999
mnd2: a new mouse model of inherited motor neuron disease.
Jones JM, Albin RL, Feldman EL, Simin K, Schuster TG, Dunnick WA, Collins JT, Chrisp CE, Taylor BA, Meisler MH., Genomics 16(3), 1993
PMID: 8325640

Womack, J. Hered. 71(), 1982
The mouse mutation muscle deficient (mdf) is characterized by a progressive motoneuron disease.
Blot S, Poirier C, Dreyfus PA., J. Neuropathol. Exp. Neurol. 54(6), 1995
PMID: 7595654

AUTHOR UNKNOWN, 0
A matrix metalloproteinase expressed on the surface of invasive tumour cells.
Sato H, Takino T, Okada Y, Cao J, Shinagawa A, Yamamoto E, Seiki M., Nature 370(6484), 1994
PMID: 8015608
White matter microglia produce membrane-type matrix metalloprotease, an activator of gelatinase A, in human brain tissues.
Yamada T, Yoshiyama Y, Sato H, Seiki M, Shinagawa A, Takahashi M., Acta Neuropathol. 90(5), 1995
PMID: 8560972
Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors.
Nakada M, Nakamura H, Ikeda E, Fujimoto N, Yamashita J, Sato H, Seiki M, Okada Y., Am. J. Pathol. 154(2), 1999
PMID: 10027400
TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3.
Amour A, Slocombe PM, Webster A, Butler M, Knight CG, Smith BJ, Stephens PE, Shelley C, Hutton M, Knauper V, Docherty AJ, Murphy G., FEBS Lett. 435(1), 1998
PMID: 9755855
The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3.
Amour A, Knight CG, Webster A, Slocombe PM, Stephens PE, Knauper V, Docherty AJ, Murphy G., FEBS Lett. 473(3), 2000
PMID: 10818225
Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1.
Gomis-Ruth FX, Maskos K, Betz M, Bergner A, Huber R, Suzuki K, Yoshida N, Nagase H, Brew K, Bourenkov GP, Bartunik H, Bode W., Nature 389(6646), 1997
PMID: 9288970
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas.
Nakano A, Tani E, Miyazaki K, Yamamoto Y, Furuyama J., J. Neurosurg. 83(2), 1995
PMID: 7616276
In vitro expression of MMP-2 and MMP-9 in glioma cells following exposure to inflammatory mediators.
Esteve PO, Tremblay P, Houde M, St-Pierre Y, Mandeville R., Biochim. Biophys. Acta 1403(1), 1998
PMID: 9622599
Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules.
Ohuchi E, Imai K, Fujii Y, Sato H, Seiki M, Okada Y., J. Biol. Chem. 272(4), 1997
PMID: 8999957
Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5.
Koshikawa N, Giannelli G, Cirulli V, Miyazaki K, Quaranta V., J. Cell Biol. 148(3), 2000
PMID: 10662785

Export

Markieren/ Markierung löschen
Markierte Publikationen

Open Data PUB

Web of Science

Dieser Datensatz im Web of Science®

Quellen

PMID: 11007969
PubMed | Europe PMC

Suchen in

Google Scholar