Ionic conductivity of electroporated lipid bilayer membranes

Kakorin S, Neumann E (2002)

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The ionic conductivity of lipid membrane pores has been theoretically analysed in terms of electrostatic interactions of the transported ions with the low-dielectric pore wall for a commonly encountered case of unequal concentrations of electrolyte on the two sides of curved lipid membranes. Theoretical analysis of the data on the conductivity of the electroporated membrane of lipid vesicles (Lecithin 20%) of radius a=90 nm yields the molar energy of interaction of a small monovalent ion with a pore wall w(0)=9+/-1 RT (or w(0)=22+/-kJ mol(-1)), corresponding to a mean pore radius of (r) over bar (p)=0.56+/-0.05 nm. The proposed theoretical approach provides a tool for the analysis and description of the nonlinear current-voltage dependencies in membrane pores and channels. (C) 2002 Published by Elsevier Science B.V.
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Kakorin S, Neumann E. Ionic conductivity of electroporated lipid bilayer membranes. In: BIOELECTROCHEMISTRY. Vol 56. ELSEVIER SCIENCE SA; 2002: 163-166.
Kakorin, S., & Neumann, E. (2002). Ionic conductivity of electroporated lipid bilayer membranes. BIOELECTROCHEMISTRY, 56(1-2), 163-166.
Kakorin, S., and Neumann, E. (2002). “Ionic conductivity of electroporated lipid bilayer membranes” in BIOELECTROCHEMISTRY, vol. 56, (ELSEVIER SCIENCE SA), 163-166.
Kakorin, S., & Neumann, E., 2002. Ionic conductivity of electroporated lipid bilayer membranes. In BIOELECTROCHEMISTRY. no.56 ELSEVIER SCIENCE SA, pp. 163-166.
S. Kakorin and E. Neumann, “Ionic conductivity of electroporated lipid bilayer membranes”, BIOELECTROCHEMISTRY, vol. 56, ELSEVIER SCIENCE SA, 2002, pp.163-166.
Kakorin, S., Neumann, E.: Ionic conductivity of electroporated lipid bilayer membranes. BIOELECTROCHEMISTRY. 56, p. 163-166. ELSEVIER SCIENCE SA (2002).
Kakorin, Sergej, and Neumann, Eberhard. “Ionic conductivity of electroporated lipid bilayer membranes”. BIOELECTROCHEMISTRY. ELSEVIER SCIENCE SA, 2002.Vol. 56. 163-166.
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10 Citations in Europe PMC

Data provided by Europe PubMed Central.

Mechanisms of transfer of bioactive molecules through the cell membrane by electroporation.
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PMID: 25939984
Basic features of a cell electroporation model: illustrative behavior for two very different pulses.
Son RS, Smith KC, Gowrishankar TR, Vernier PT, Weaver JC., J. Membr. Biol. 247(12), 2014
PMID: 25048527
Theoretical and experimental analysis of electroporated membrane conductance in cell suspension.
Suzuki DO, Ramos A, Ribeiro MC, Cazarolli LH, Silva FR, Leite LD, Marques JL., IEEE Trans Biomed Eng 58(12), 2011
PMID: 21193368
Effect of acetylsalicylic acid on the current-voltage characteristics of planar lipid membranes.
Watala C, Drapeza A, Loban V, Asztemborska M, Shcharbin D., Biophys. Chem. 142(1-3), 2009
PMID: 19321250
Kinetics of transmembrane transport of small molecules into electropermeabilized cells.
Pucihar G, Kotnik T, Miklavcic D, Teissie J., Biophys. J. 95(6), 2008
PMID: 18539632
Model of creation and evolution of stable electropores for DNA delivery.
Smith KC, Neu JC, Krassowska W., Biophys. J. 86(5), 2004
PMID: 15111399
Electrical energy required to form large conducting pores.
Neu JC, Smith KC, Krassowska W., Bioelectrochemistry 60(1-2), 2003
PMID: 12893316

11 References

Data provided by Europe PubMed Central.

The electrical breakdown of cell and lipid membranes: the similarity of phenomenologies.
Chernomordik LV, Sukharev SI, Popov SV, Pastushenko VF, Sokirko AV, Abidor IG, Chizmadzhev YA., Biochim. Biophys. Acta 902(3), 1987
PMID: 3620466
Reversible electrical breakdown of lipid bilayers: formation and evolution of pores.
Glaser RW, Leikin SL, Chernomordik LV, Pastushenko VF, Sokirko AI., Biochim. Biophys. Acta 940(2), 1988
PMID: 2453213
Perspectives for microelectrode arrays for biosensing and membrane electroporation.
Neumann E, Tonsing K, Siemens P., Bioelectrochemistry 51(2), 2000
PMID: 10910160
Fundamentals of electroporative delivery of drugs and genes.
Neumann E, Kakorin S, Toensing K., Bioelectrochem Bioenerg 48(1), 1999
PMID: 10228565
Ion-membrane interactions as structural forces.
Parsegian VA., Ann. N. Y. Acad. Sci. 264(), 1975
PMID: 1062955
Kinetics of the electroporative deformation of lipid vesicles
Kakorin, Ber. Bunsen-Ges. Phys. Chem. 102(), 1998
Electroporative deformation of salt-filled vesicles
Kakorin, Eur. Biophys. J. 27(), 1998
Membrane electroporation and electromechanical deformation of vesicles and cells
Neumann, Faraday Discuss. 111(), 1998

Adam, 1988
On the LambertW function
Corless, Adv. Comput. Math. 5(), 1996


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